UniProtKB - Q9VSC2 (Q9VSC2_DROME)
Protein
Submitted name:
Extra-extra
Gene
exex
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 439 – 498 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
GO - Biological processi
- axon target recognition Source: FlyBase
- central nervous system development Source: FlyBase
- nervous system development Source: FlyBase
- neuroendocrine cell differentiation Source: FlyBase
- neuron projection morphogenesis Source: GO_Central
- spinal cord motor neuron cell fate specification Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Extra-extraImportedSubmitted name: RE39081pImported |
Gene namesi | Name:exexImported Synonyms:DHB9Imported, dHB9Imported, dHb9Imported, dhb9Imported, Dmel\CG8254Imported, ExexImported, HB9Imported, Hb9Imported, hb9Imported ORF Names:CG8254Imported, Dmel_CG8254Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0041156, exex |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | FBgn0041156, Expressed in digestive system element and 43 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9VSC2, 5 interactors |
STRINGi | 7227.FBpp0076468 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 437 – 497 | HomeoboxInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 159 | DisorderedSequence analysisAdd BLAST | 159 | |
Regioni | 178 – 198 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 292 – 334 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 496 – 525 | DisorderedSequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 19 – 35 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 43 – 117 | PolarSequence analysisAdd BLAST | 75 | |
Compositional biasi | 123 – 159 | Pro-richSequence analysisAdd BLAST | 37 | |
Compositional biasi | 178 – 192 | Pro-richSequence analysisAdd BLAST | 15 | |
Compositional biasi | 303 – 325 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 507 – 525 | PolarSequence analysisAdd BLAST | 19 |
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG0489, Eukaryota |
GeneTreei | ENSGT00940000164719 |
HOGENOMi | CLU_471965_0_0_1 |
OMAi | GCEDQQP |
OrthoDBi | 858478at2759 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR020479, Homeobox_metazoa IPR042768, MNX1/Ceh-12 |
PANTHERi | PTHR24335, PTHR24335, 1 hit |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit |
PRINTSi | PR00024, HOMEOBOX |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VSC2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSAQVSQQP PPPPLTASSS TSMPSQLLLS HIQHHSSSLH HQRSHQRSSP
60 70 80 90 100
PAQDYDQGSN QSTLSPRSQI TPSPPAASPT HSAATTGSPV STYTPALSPG
110 120 130 140 150
GAQDSSQTES GQSSQMPLLV APMPVGTGPP HSHPPPPHPR LYVEGFPPPH
160 170 180 190 200
HVPHPHPALG TYPLPRLPLM LPANPPGVPS GAAAPPPVSP QPAANHLSHS
210 220 230 240 250
GATMATTTLL PPAQSQPKKS FCIDALLAKS QHQSGEPQPI IVDDRLAALH
260 270 280 290 300
YARDQAELNH AFVTASNAAA AAQAAASAAG GISEQEALQR IRDSREYDSP
310 320 330 340 350
SPDGMSRSES PTSSHRSSPP ISPGCEDQQQ PHGALHPQHL SMRMSDFHDE
360 370 380 390 400
FKKPIPPHSP IRPQDFPLYA GGHPYQLLAQ GGSAFHRPLD PSGKPIPIPM
410 420 430 440 450
GHNFMPSQLQ FEFLARAGML HHRIPELAAY PHHAILGKTR RPRTAFTSQQ
460 470 480 490 500
LLELEKQFKQ NKYLSRPKRF EVASGLMLSE TQVKIWFQNR RMKWKRSKKA
510 520
QQEAKERAKA NQQQQQQQQT PSAAS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF50503.1 AY084165 mRNA Translation: AAL89903.1 |
RefSeqi | NP_648164.1, NM_139907.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0076751; FBpp0076468; FBgn0041156 |
GeneIDi | 38884 |
KEGGi | dme:Dmel_CG8254 |
UCSCi | CG8254-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF50503.1 AY084165 mRNA Translation: AAL89903.1 |
RefSeqi | NP_648164.1, NM_139907.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9VSC2, 5 interactors |
STRINGi | 7227.FBpp0076468 |
Genome annotation databases
EnsemblMetazoai | FBtr0076751; FBpp0076468; FBgn0041156 |
GeneIDi | 38884 |
KEGGi | dme:Dmel_CG8254 |
UCSCi | CG8254-RA, d. melanogaster |
Organism-specific databases
CTDi | 38884 |
FlyBasei | FBgn0041156, exex |
Phylogenomic databases
eggNOGi | KOG0489, Eukaryota |
GeneTreei | ENSGT00940000164719 |
HOGENOMi | CLU_471965_0_0_1 |
OMAi | GCEDQQP |
OrthoDBi | 858478at2759 |
Miscellaneous databases
BioGRID-ORCSi | 38884, 0 hits in 3 CRISPR screens |
GenomeRNAii | 38884 |
Gene expression databases
Bgeei | FBgn0041156, Expressed in digestive system element and 43 other tissues |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR020479, Homeobox_metazoa IPR042768, MNX1/Ceh-12 |
PANTHERi | PTHR24335, PTHR24335, 1 hit |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit |
PRINTSi | PR00024, HOMEOBOX |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VSC2_DROME | |
Accessioni | Q9VSC2Primary (citable) accession number: Q9VSC2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 10, 2021 | |
This is version 183 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |