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Protein

60S ribosomal protein L18

Gene

RpL18

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L18
Gene namesi
Name:RpL18
ORF Names:CG8615
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0035753 RpL18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002916281 – 18860S ribosomal protein L18Add BLAST188

Proteomic databases

PaxDbiQ9VS34
PRIDEiQ9VS34

Expressioni

Gene expression databases

BgeeiFBgn0035753
ExpressionAtlasiQ9VS34 baseline and differential
GenevisibleiQ9VS34 DM

Interactioni

Protein-protein interaction databases

BioGridi64237, 17 interactors
IntActiQ9VS34, 17 interactors
MINTiQ9VS34
STRINGi7227.FBpp0076602

Structurei

3D structure databases

ProteinModelPortaliQ9VS34
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1714 Eukaryota
COG1727 LUCA
GeneTreeiENSGT00390000012976
InParanoidiQ9VS34
KOiK02883
OMAiKHHVKKG
OrthoDBiEOG091G07WU
PhylomeDBiQ9VS34

Family and domain databases

InterProiView protein in InterPro
IPR036227 L18e/L15P_sf
IPR000039 Ribosomal_L18e
IPR021131 Ribosomal_L18e/L15P
IPR021132 Ribosomal_L18e_CS
PANTHERiPTHR10934 PTHR10934, 1 hit
PfamiView protein in Pfam
PF17135 Ribosomal_L18, 1 hit
SUPFAMiSSF52080 SSF52080, 1 hit
PROSITEiView protein in PROSITE
PS01106 RIBOSOMAL_L18E, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VS34-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIDINHKYD RKVRRTEPKS QDVYLRLLVK LYRFLQRRTN KKFNRIILKR
60 70 80 90 100
LFMSKINRPP LSLQRIARFF KAANQPESTI VVVGTVTDDA RLLVVPKLTV
110 120 130 140 150
CALHVTQTAR ERILKAGGEV LTFDQLALRS PTGKNTLLLQ GRRTARTACK
160 170 180
HFGKAPGVPH SHTRPYVRSK GRKFERARGR RSSCGYKK
Length:188
Mass (Da):21,665
Last modified:May 1, 2000 - v1
Checksum:i2C1818189704FB9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF50596.1
AY113554 mRNA Translation: AAM29559.1
BT030448 mRNA Translation: ABP87890.1
RefSeqiNP_001261501.1, NM_001274572.1
NP_001286966.1, NM_001300037.1
NP_648091.1, NM_139834.3
UniGeneiDm.7265
Dm.7423

Genome annotation databases

EnsemblMetazoaiFBtr0076892; FBpp0076602; FBgn0035753
FBtr0333370; FBpp0305562; FBgn0035753
FBtr0345036; FBpp0311286; FBgn0035753
GeneIDi38794
KEGGidme:Dmel_CG8615

Similar proteinsi

Entry informationi

Entry nameiRL18_DROME
AccessioniPrimary (citable) accession number: Q9VS34
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: May 1, 2000
Last modified: July 18, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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