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Entry version 132 (16 Oct 2019)
Sequence version 2 (01 Oct 2002)
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Protein
Submitted name:

Fiery mountain, isoform A

Gene

fmt

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Fiery mountain, isoform AImported
Submitted name:
Fiery mountain, isoform CImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fmtImported
Synonyms:Dmel\CG10289Imported, PpV[[R]]Imported
ORF Names:CG10289Imported, Dmel_CG10289Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0035688 fmt

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9VRV1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0035688 Expressed in 31 organ(s), highest expression level in egg chamber

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VRV1 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni492 – 575DisorderedSequence analysisAdd BLAST84
Regioni729 – 757DisorderedSequence analysisAdd BLAST29
Regioni814 – 850DisorderedSequence analysisAdd BLAST37
Regioni922 – 945DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili10 – 30Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi501 – 516PolyampholyteSequence analysisAdd BLAST16
Compositional biasi527 – 545PolyampholyteSequence analysisAdd BLAST19
Compositional biasi546 – 575PolarSequence analysisAdd BLAST30

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2073 Eukaryota
ENOG410XRM1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000009899

Identification of Orthologs from Complete Genome Data

More...
OMAi
WDMDVQF

Database of Orthologous Groups

More...
OrthoDBi
172613at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007587 SAPS

The PANTHER Classification System

More...
PANTHERi
PTHR12634 PTHR12634, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04499 SAPS, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9VRV1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFWDKGYAPS ANIEALLEKE NSTLEEFLDE EDILQECKTQ KKNLVNYFTR
60 70 80 90 100
PEVIRRLVEL ITTEPSEDVP MSKRFRYANM SCEILTLGLP SLDEKLLNDA
110 120 130 140 150
ETLQLLYSYL EKEPPLNPLL SSFFSKTFSM LFTKKPEQDW FLYQHMCLQL
160 170 180 190 200
LEYIKSQKTF LDFICKHFDT PVIPDLIMQM MKDIEGGRLK RNLFEWLTED
210 220 230 240 250
KIVERLIAIL RNPQETDKHA NVADFFCDLI NQGRLMRQTE QENDSFEPAF
260 270 280 290 300
DGSNPILKTI EFADTIEALL NVILEPNAQE SAILSGISVV LTLIKPITFT
310 320 330 340 350
DEPNSDRQRL LQKREREIHQ EVQETVITVM APRLQEFVHI LKNPPAKPTL
360 370 380 390 400
ETTAAVLTPP FGKTRLQVCR VFTALLETKH ETIQQAICAT EYFSLLLDFF
410 420 430 440 450
KQYCWNNFLH TEMEKALYVV FYNELSNNNT ASTEVTDYFT ADCLINAFLK
460 470 480 490 500
VGTEESEVEM KNALNDAKRA EGGKDEEGGD IEIEVAAAQE VAAQTPDERQ
510 520 530 540 550
TAAEENQEHE EHMSQVEAAA EATASEDAEP KAQDNEVKNS EVDGESPTDQ
560 570 580 590 600
QESEATLNDL DKTKTVPSPP PSEMQSHLIV NCHLISKLVD LWQHNAQAQS
610 620 630 640 650
AEKGRRLGYM GHLIKILRHI TNCISESEHI GDLITSSLSD EDEVKLWQSL
660 670 680 690 700
IDAETGEFSL AVKQQTKLLA DCNPHEENQY NDGSNDYTGE INAWNVGNLP
710 720 730 740 750
YREVDCSELN NTLQDIFFAI DQNRFQFGRN IDDEDDDDDE HGDHSGGGDG
760 770 780 790 800
HGHGMFTKNS NTLNNLADPW DIQFAVLSSA PTQVNTGTAN WGTDFNSDNF
810 820 830 840 850
ADFDAHFSTF GSDLGMPISA PPGEEEEEDS SPAPESATQV NPEEERQPAE
860 870 880 890 900
SIGLAVGKGV QDNLACTDDQ QAEYDNNANV EKAISDKLAE SSVVETAAIV
910 920 930 940 950
TRLQSVLLDG EDDYEDDEGM WTKPLGADRP SETEQITPIS NGPDSKVNEF
960 970 980 990
NHANDISSNN VDGHEANITT EQQKLAAAAK TNNVEIATTT T
Length:991
Mass (Da):111,194
Last modified:October 1, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE89B6F614478217C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PEH8M9PEH8_DROME
Fiery mountain, isoform D
fmt Dmel\CG10289, PpV[[R]], CG10289, Dmel_CG10289
996Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PEB1M9PEB1_DROME
Fiery mountain, isoform B
fmt Dmel\CG10289, PpV[[R]], CG10289, Dmel_CG10289
967Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF50681.2
AE014296 Genomic DNA Translation: AGB94164.1

NCBI Reference Sequences

More...
RefSeqi
NP_001261469.1, NM_001274540.1
NP_648033.2, NM_139776.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0077019; FBpp0076727; FBgn0035688
FBtr0331790; FBpp0304175; FBgn0035688

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
38714

UCSC genome browser

More...
UCSCi
CG10289-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF50681.2
AE014296 Genomic DNA Translation: AGB94164.1
RefSeqiNP_001261469.1, NM_001274540.1
NP_648033.2, NM_139776.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiQ9VRV1

Genome annotation databases

EnsemblMetazoaiFBtr0077019; FBpp0076727; FBgn0035688
FBtr0331790; FBpp0304175; FBgn0035688
GeneIDi38714
UCSCiCG10289-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
38714
FlyBaseiFBgn0035688 fmt

Phylogenomic databases

eggNOGiKOG2073 Eukaryota
ENOG410XRM1 LUCA
GeneTreeiENSGT00390000009899
OMAiWDMDVQF
OrthoDBi172613at2759

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
38714

Gene expression databases

BgeeiFBgn0035688 Expressed in 31 organ(s), highest expression level in egg chamber
ExpressionAtlasiQ9VRV1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007587 SAPS
PANTHERiPTHR12634 PTHR12634, 2 hits
PfamiView protein in Pfam
PF04499 SAPS, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VRV1_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VRV1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: October 16, 2019
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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