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UniProtKB - Q9VQL7 (Q9VQL7_DROME)

Entry version 165 (07 Apr 2021)
Sequence version 1 (01 May 2000)
Previous versions | rss
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Protein

3-oxoacyl-[acyl-carrier-protein] reductase

Gene

FASN1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.ARBA annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.ARBA annotation
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferaseImported, HydrolaseImported, LyaseARBA annotation, Multifunctional enzymeARBA annotation, OxidoreductaseImported, Transferase
Biological processFatty acid biosynthesisARBA annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandNADPARBA annotation, Pyridoxal phosphateARBA annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00094

Protein family/group databases

ESTHER database of the Alpha/Beta-hydrolase fold superfamily of proteins

More...ESTHERi		drome-CG3523, Thioesterase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductaseARBA annotation (EC:1.1.1.100ARBA annotation, EC:1.3.1.39ARBA annotation, EC:2.3.1.41ARBA annotation, EC:3.1.2.14ARBA annotation)
Alternative name(s):
3-oxoacyl-[acyl-carrier-protein] synthaseARBA annotation
Acyl-[acyl-carrier-protein] hydrolaseARBA annotation
Enoyl-[acyl-carrier-protein] reductaseARBA annotation
[Acyl-carrier-protein] S-acetyltransferaseARBA annotation
[Acyl-carrier-protein] S-malonyltransferaseARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FASN1Imported
Synonyms:anon-EST:Posey235Imported, anon-EST:Posey43Imported, anon-WO0138581.1Imported, BcDNA:GH07626Imported, BcDNA:gh07626Imported, dFASImported, dFASNImported, dFASN1Imported, DM_7295848Imported, Dmel\CG3523Imported, FASImported, FasImported, fasImported, FAS[CG3523]Imported, FASNImported, FasnImported, Fasn1Imported, FASN[CG3523]Imported, Fatty acid synthaseImported
ORF Names:CG3523Imported, Dmel_CG3523Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0283427, FASN1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2081O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation, S-nitrosylationARBA annotation

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		Q9VQL7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0027571, Expressed in arthropod fat body and 39 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9VQL7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9VQL7, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q9VQL7, 3 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9VQL7

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2046 – 2123CarrierInterPro annotationAdd BLAST78

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157276

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000022_31_7_1

Identification of Orthologs from Complete Genome Data

More...OMAi		CKVYYAS

Database of Orthologous Groups

More...OrthoDBi		19161at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1200.10, 1 hit
1.10.1470.20, 1 hit
3.10.129.110, 1 hit
3.40.366.10, 1 hit
3.40.47.10, 1 hit
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029058, AB_hydrolase
IPR001227, Ac_transferase_dom_sf
IPR036736, ACP-like_sf
IPR014043, Acyl_transferase
IPR016035, Acyl_Trfase/lysoPLipase
IPR013149, ADH_C
IPR023102, Fatty_acid_synthase_dom_2
IPR011032, GroES-like_sf
IPR018201, Ketoacyl_synth_AS
IPR014031, Ketoacyl_synth_C
IPR014030, Ketoacyl_synth_N
IPR016036, Malonyl_transacylase_ACP-bd
IPR036291, NAD(P)-bd_dom_sf
IPR032821, PKS_assoc
IPR020841, PKS_Beta-ketoAc_synthase_dom
IPR020807, PKS_dehydratase
IPR042104, PKS_dehydratase_sf
IPR020843, PKS_ER
IPR013968, PKS_KR
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR001031, Thioesterase
IPR016039, Thiolase-like

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00698, Acyl_transf_1, 1 hit
PF00107, ADH_zinc_N, 1 hit
PF16197, KAsynt_C_assoc, 1 hit
PF00109, ketoacyl-synt, 1 hit
PF02801, Ketoacyl-synt_C, 1 hit
PF08659, KR, 1 hit
PF00550, PP-binding, 1 hit
PF14765, PS-DH, 1 hit
PF00975, Thioesterase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00827, PKS_AT, 1 hit
SM00826, PKS_DH, 1 hit
SM00829, PKS_ER, 1 hit
SM00825, PKS_KS, 1 hit
SM00823, PKS_PP, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47336, SSF47336, 1 hit
SSF50129, SSF50129, 1 hit
SSF51735, SSF51735, 2 hits
SSF52151, SSF52151, 1 hit
SSF53474, SSF53474, 1 hit
SSF53901, SSF53901, 1 hit
SSF55048, SSF55048, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00606, B_KETOACYL_SYNTHASE, 1 hit
PS50075, CARRIER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VQL7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPARFAEEVI TAEPAQRAAP QLDLGGGHYV PRQQHLNDEI AITGFSGRLP 
        60         70         80         90        100
ESSTIEEFKQ NLFDGVDMVN DDPRRWERGL YGLPDRIGKL KDSDLENFDQ 
       110        120        130        140        150
QFFGVHQKQA ECMDPLLRML LELTHEAIID AGLNPSDLRG SRTGVYIGVS 
       160        170        180        190        200
NSETEQHWCS DADRVNGYGL TGCARAMFAN RISFTFDFKG PSYSIDTACS 
       210        220        230        240        250
SSLYALEQAF SDMREGKVDN ALVAGAGLIL KPTMSLQFKR LNMLSPDGSC 
       260        270        280        290        300
KAFDESGNGY VRSDGCVVLL LQRTSAARRV YASILNVRTN TDGFKEQGIT 
       310        320        330        340        350
YPIGKMQNRL IRETYEEIGL NPADVVYVEA HGTGTKVGDP QEVNSITDFF 
       360        370        380        390        400
CKDRTTPLLI GSVKSNMGHS EPASGVCSVA KILIAMEEGV IPGNLHYNKP 
       410        420        430        440        450
NPDLYGLVDG RLKVVDRNLP WNGGIIGLNS FGFGGANAHV ILKSNPKPKA 
       460        470        480        490        500
LTPKDGALKV VLASGRTFEA VEQLLESAST NADDDEYLQL INEIHSKAIP 
       510        520        530        540        550
NHFFRGYGVV SSKGTHQREV IESNDDKRPI WYIYSGMGSQ WASMAKDLMK 
       560        570        580        590        600
IEAFAKTIQR CADVLKPEGV DLIDVLTRST DKSFENILNS FISIAAMQVA 
       610        620        630        640        650
LTDLLSSLGI HPDGIVGHSV GELGCAYADG CFTPEQTVLA AYWRGKSILD 
       660        670        680        690        700
TQLAKGKMAA VGLSWEDAHS RVPSDCFPVC HNSEDNCTIS GPEASIEALV 
       710        720        730        740        750
AKLNAEGVFA KAVNSSGYAF HSKYIAEAGP KLRKSLEKII PNAKNRTARW 
       760        770        780        790        800
ISTSIPESAW NTPVAKQSSA AYHVNNLLSP VLFHEALQHV PKNAISVEIA 
       810        820        830        840        850
PHGLLQAILK RALGPDATNL SLVKRGHENN VEFFLTNVGK LFAAGAQPQV 
       860        870        880        890        900
LTLVRPISYP VGRGTPMLNS KVGWDHTQKW LVAKFGKETS SGETIVEVDL 
       910        920        930        940        950
SKEDDAFLAG HTIDGRILFP ATGYMTLAWQ TFAKMQGSEF HKTPVVMENL 
       960        970        980        990       1000
VFHRATILNK NAVVKFGINF FDGTGAFEIC ESGSLAVSGK ITIPESIDNE 
      1010       1020       1030       1040       1050
ELPLEEQTPS AVAKELGTND VYKELRLRGY DYGGIFRGIV RSDTVASTGK 
      1060       1070       1080       1090       1100
LQWVDNWISF MDTMLQFSIL SKNLRELYLP TRIERAVINP AKHFELLSAL 
      1110       1120       1130       1140       1150
TKEEQVETGL PVQWYSDINV IKSAGVELRG LKANLAQRRP GTQAPPTLER 
      1160       1170       1180       1190       1200
YQFVPNINTT DLNENSEKAR LHALDVAIQV IIENSSGAVK LKGVELANGR 
      1210       1220       1230       1240       1250
NPDVLVANRL LQIIEGEPVL TGDVAVVTSN NNEETITAAL GDSGVRVVSK 
      1260       1270       1280       1290       1300
DVLKEPVEQN CHFVFGIDVL SRPDTKTLEN SIASIRENGF LILEETLPTY 
      1310       1320       1330       1340       1350
TKTGRALLTK FGFVAVQEQS LGATRVLVLA RKAVDLKTRK SVVVVATEQN 
      1360       1370       1380       1390       1400
FNWVDDLKAA LATAATEEQY VYVVCQGEEL FGAVGLMTCI KNENGGKLAR 
      1410       1420       1430       1440       1450
LVFVQDAKAE KFSLTSTLYR QQLEKDLISN VLKNGAWGTF RHLKLETQQA 
      1460       1470       1480       1490       1500
TLQVEHAYVN ALVKGDLASL KWIEAAQADT AATVDKNLET CTVYYAPINF 
      1510       1520       1530       1540       1550
RDVMLTSGKL AADALPGDLA EQDCVLGLEF AGRDTQGRRV MAMVPAKSLA 
      1560       1570       1580       1590       1600
TTCVASKRMM WQIPEKWTME EASTVPCVYS TVYYALVVRG QMKKGEKILI 
      1610       1620       1630       1640       1650
HAGSGGVGQA AISVALAHGL TVFTTVGSKE KREFLLKRFP KLQERNIGNS 
      1660       1670       1680       1690       1700
RDTSFEQLVL RETKGRGVDL VLNSLSEEKL QASIRCLGLN GRFLEIGKFD 
      1710       1720       1730       1740       1750
LSNNSPLGMS VFLKNTSFHG ILLDSVMEGE EEMQNQVVSL VAEGIKTGAV 
      1760       1770       1780       1790       1800
VPLPTSVFND QQVEQAFRFM ASGKHIGKVV IKVRDEEAGK KALQPKPRLI 
      1810       1820       1830       1840       1850
NAIPRTYMHP EKSYILVGGL GGFGLELTNW LVTRGARYIV LTSRSGVKTG 
      1860       1870       1880       1890       1900
YQGLMIRRWQ ERGVKVVIDT SDVTTAAGAK KLLENSNKLA LVGGIFNLAA 
      1910       1920       1930       1940       1950
VLRDALIEDQ TAKDFKTVAD PKVTATKYLD QFSRDICTEL DYFICFSSVS 
      1960       1970       1980       1990       2000
CGRGNIGQTN YGLANSAMER ICEQRQVSGF PGTAIQWGAI GDTGLVLENL 
      2010       2020       2030       2040       2050
GDNDTVIGGT LPQRMPSCLQ TIDLFLQQPH PVVASMVVAE KRKSDQSAGV 
      2060       2070       2080       2090       2100
SLIATIANIL GLRDTKNIQD GASLADLGMD SLMSAEIKQT LERNFDIVLS 
      2110       2120       2130       2140       2150
AQEIRQLTFG ALKAMDGGAD VKPAAAAPAA AAGVPEANIT SGGSSRTASP 
      2160       2170       2180       2190       2200
MGDGTQVVFT TSLIPTEAIV QLDTKAPANS KQSPIFFISP IEGFASALEP 
      2210       2220       2230       2240       2250
LAKRLEVPAY GLQYTEAVPS DSLESAAKFF IKQLRTVQPK GPYKLAGYSF 
      2260       2270       2280       2290       2300
GCLLTYVMAG ILEETNEVAN VIMLDGAPSY VNWYTSSFKQ RYTDGTNADN 
      2310       2320       2330       2340       2350
DNQSYGLAYF GIVLANIDYK ALVRLLIVIP TWEEKLERFA ELMSNEITQP 
      2360       2370       2380       2390       2400
VETIKKSATL FYKKLELADG YQPTLKLKTN VTLVKPTDNS AKLDEDYRLK 
      2410       2420       2430 
EVCTKPVEVH TVEGNHRTFL IEDQSLKTIQ SILKRLFN
Length:2,438
Mass (Da):266,444
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD336104713119865
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B7Z001B7Z001_DROME
3-oxoacyl-[acyl-carrier-protein] re...
FASN1 anon-EST:Posey235, anon-EST:Posey43, anon-WO0138581.1, BcDNA:GH07626, BcDNA:gh07626
2,540Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF51148.1

NCBI Reference Sequences

More...RefSeqi		NP_608748.1, NM_134904.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0077659; FBpp0077343; FBgn0283427

Database of genes from NCBI RefSeq genomes

More...GeneIDi		33524

UCSC genome browser

More...UCSCi		CG3523-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF51148.1
RefSeqiNP_608748.1, NM_134904.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6FN6X-ray2.70A/B889-2036[»]
SMRiQ9VQL7
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiQ9VQL7, 3 interactors

Protein family/group databases

ESTHERidrome-CG3523, Thioesterase

Proteomic databases

PRIDEiQ9VQL7

Genome annotation databases

EnsemblMetazoaiFBtr0077659; FBpp0077343; FBgn0283427
GeneIDi33524
UCSCiCG3523-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		33524
FlyBaseiFBgn0283427, FASN1

Phylogenomic databases

GeneTreeiENSGT00940000157276
HOGENOMiCLU_000022_31_7_1
OMAiCKVYYAS
OrthoDBi19161at2759

Enzyme and pathway databases

UniPathwayiUPA00094

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		33524, 1 hit in 3 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FASN1, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		33524

Gene expression databases

BgeeiFBgn0027571, Expressed in arthropod fat body and 39 other tissues
ExpressionAtlasiQ9VQL7, baseline and differential
GenevisibleiQ9VQL7, DM

Family and domain databases

Gene3Di1.10.1200.10, 1 hit
1.10.1470.20, 1 hit
3.10.129.110, 1 hit
3.40.366.10, 1 hit
3.40.47.10, 1 hit
3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058, AB_hydrolase
IPR001227, Ac_transferase_dom_sf
IPR036736, ACP-like_sf
IPR014043, Acyl_transferase
IPR016035, Acyl_Trfase/lysoPLipase
IPR013149, ADH_C
IPR023102, Fatty_acid_synthase_dom_2
IPR011032, GroES-like_sf
IPR018201, Ketoacyl_synth_AS
IPR014031, Ketoacyl_synth_C
IPR014030, Ketoacyl_synth_N
IPR016036, Malonyl_transacylase_ACP-bd
IPR036291, NAD(P)-bd_dom_sf
IPR032821, PKS_assoc
IPR020841, PKS_Beta-ketoAc_synthase_dom
IPR020807, PKS_dehydratase
IPR042104, PKS_dehydratase_sf
IPR020843, PKS_ER
IPR013968, PKS_KR
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR001031, Thioesterase
IPR016039, Thiolase-like
PfamiView protein in Pfam
PF00698, Acyl_transf_1, 1 hit
PF00107, ADH_zinc_N, 1 hit
PF16197, KAsynt_C_assoc, 1 hit
PF00109, ketoacyl-synt, 1 hit
PF02801, Ketoacyl-synt_C, 1 hit
PF08659, KR, 1 hit
PF00550, PP-binding, 1 hit
PF14765, PS-DH, 1 hit
PF00975, Thioesterase, 1 hit
SMARTiView protein in SMART
SM00827, PKS_AT, 1 hit
SM00826, PKS_DH, 1 hit
SM00829, PKS_ER, 1 hit
SM00825, PKS_KS, 1 hit
SM00823, PKS_PP, 1 hit
SUPFAMiSSF47336, SSF47336, 1 hit
SSF50129, SSF50129, 1 hit
SSF51735, SSF51735, 2 hits
SSF52151, SSF52151, 1 hit
SSF53474, SSF53474, 1 hit
SSF53901, SSF53901, 1 hit
SSF55048, SSF55048, 1 hit
PROSITEiView protein in PROSITE
PS00606, B_KETOACYL_SYNTHASE, 1 hit
PS50075, CARRIER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VQL7_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VQL7
Secondary accession number(s): Q9Y129
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 7, 2021
This is version 165 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Proteomics identificationCombined sources, Reference proteomeImported
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