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Protein

Palmitoyltransferase

Gene

GABPI

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • ER to Golgi vesicle-mediated transport Source: FlyBase
  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:GABPIImported
Synonyms:Dmel\CG17257Imported
ORF Names:CG17257Imported, Dmel_CG17257Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0031495 GABPI

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei121 – 137HelicalUniRule annotationAdd BLAST17
Transmembranei149 – 167HelicalUniRule annotationAdd BLAST19
Transmembranei179 – 196HelicalUniRule annotationAdd BLAST18
Transmembranei308 – 330HelicalUniRule annotationAdd BLAST23
Transmembranei364 – 384HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9VQK9

Expressioni

Gene expression databases

BgeeiFBgn0031495

Interactioni

Protein-protein interaction databases

IntActiQ9VQK9, 2 interactors
STRINGi7227.FBpp0077337

Structurei

3D structure databases

SMRiQ9VQK9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini263 – 399DHHCInterPro annotationAdd BLAST137

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311 Eukaryota
COG5273 LUCA
GeneTreeiENSGT00880000137864
OrthoDBiEOG091G0JCR

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VQK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLMTAGTSN FLSAAWRSEA EESKSKENGS LCCCEYVAED SRERSHILGC
60 70 80 90 100
CCNCVDFDLV CTRLVTCRAI DRRNIDGMLI AFQDRLRLPW RGGAKRISPA
110 120 130 140 150
AVAPAFIVPL MLGLATLNSK TAIVLMLTLV GFTIWGMELA KRTATRTNFF
160 170 180 190 200
LSWLVFSVFY MIIIFEFQVP LLELAPEENY ALMFFSCAAL YCLYSAKALS
210 220 230 240 250
PLNLVSAQYG TTPKDELPGI AEASSGEEQA EAQTTLQMES VLSLDDDEVG
260 270 280 290 300
DMDTAERSGL MHGQPNICEI CRKVTPRRAY HCPVCGTCVK RRDHHSYWLN
310 320 330 340 350
CCIGERNYVW YIVGLALSEI ALLLGANLTL TSICHPFMVV RPLGYPVLLP
360 370 380 390 400
DDCSEVFEGF DLGISFVVAC YALLISSYIA FILARQAYLW WKGSTLHEYK
410 420
RTSNAAGRNR IWSNWRAILK
Length:420
Mass (Da):47,014
Last modified:October 1, 2002 - v2
Checksum:i6467FD9BD4169315
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF51157.2
AY069413 mRNA Translation: AAL39558.1
AE014134 Genomic DNA Translation: AAN10406.1
RefSeqiNP_608741.1, NM_134897.5
NP_722869.1, NM_164522.3
UniGeneiDm.2142

Genome annotation databases

EnsemblMetazoaiFBtr0077651; FBpp0077336; FBgn0031495
FBtr0077652; FBpp0077337; FBgn0031495
GeneIDi33516
UCSCiCG17257-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VQK9_DROME
AccessioniPrimary (citable) accession number: Q9VQK9
Secondary accession number(s): Q8T0C4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: July 18, 2018
This is version 148 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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