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UniProtKB - Q9VQC4 (GLCTK_DROME)
Protein
Glycerate kinase
Gene
Glyctk
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Catalytic activityi
- EC:2.7.1.31By similarity
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- glycerate kinase activity Source: UniProtKB
GO - Biological processi
- protein phosphorylation Source: UniProtKB
Keywordsi
Molecular function | Kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-DME-70350, Fructose catabolism |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:Glyctk ORF Names:CG9886 |
Organismi | Drosophila melanogaster (Fruit fly) |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0031428, CG9886 |
VEuPathDBi | VectorBase:FBgn0031428 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Other locations
- cytoplasm Source: UniProtKB
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000287197 | 1 – 487 | Glycerate kinaseAdd BLAST | 487 |
Proteomic databases
PaxDbi | Q9VQC4 |
Expressioni
Gene expression databases
Bgeei | FBgn0031428, Expressed in arthropod fat body and 40 other tissues |
ExpressionAtlasi | Q9VQC4, baseline and differential |
Genevisiblei | Q9VQC4, DM |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycerate kinase type-2 family.Curated
Phylogenomic databases
eggNOGi | KOG3935, Eukaryota |
GeneTreei | ENSGT00390000014365 |
HOGENOMi | CLU_032279_0_0_1 |
InParanoidi | Q9VQC4 |
OMAi | ICGGEPV |
OrthoDBi | 1371490at2759 |
PhylomeDBi | Q9VQC4 |
Family and domain databases
Gene3Di | 3.40.1480.10, 1 hit 3.40.50.10180, 1 hit |
InterProi | View protein in InterPro IPR037035, GK-like_C_sf IPR038614, GK_N_sf IPR007835, MOFRL IPR025286, MOFRL_assoc_dom IPR039760, MOFRL_protein |
PANTHERi | PTHR12227, PTHR12227, 1 hit |
Pfami | View protein in Pfam PF13660, DUF4147, 1 hit PF05161, MOFRL, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9VQC4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKRQTWEQM RQIFVQAVNA VHPEKVFADF QKFDLRPQIG ENATDISIKL
60 70 80 90 100
NGERQDISGK TCHIVGFGKA VLGMANKVQQ DLGATSAGGV LSVPVNTLKQ
110 120 130 140 150
FQQPVAPGLV VHEGAANNLP DENALKAARE IKQLAEKMTA QDILFVFISG
160 170 180 190 200
GGSALLPLPR SPLTLEDKRS IADKLMKRGA SIQEINAVRI ACSDIKGGRL
210 220 230 240 250
ARLAGQAGLL VTFVLSDIIG DPLELIACGP TIQPEAAASP SDILKKHHVW
260 270 280 290 300
EELSPEIRRV FEQPEEQKNT SLPEHKVFVV GSNVIATSTA AHEAERLGYI
310 320 330 340 350
PCVLSCAVQG DVAQVAGDYQ RLLHGIQEAK QHGILDPQLR EKYAFGERSY
360 370 380 390 400
PTFRRALEDH MSSKKPLFLI CGGEPVIKVS GHGLGGRSQH LALLMSQALH
410 420 430 440 450
RDEAMRDCTF LSAGTDGIDG PTDAAGAFGD SSVVESYLGD HTLDELAETL
460 470 480
RNCDSYNFYK NLAQGEHHVL TGHTGTNVMD LHFLVVP
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketM9PB12 | M9PB12_DROME | Uncharacterized protein, isoform B | AAF51252 Dmel\CG9886, CG9886, Dmel_CG9886 | 487 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AAF51252.1 AY061555 mRNA Translation: AAL29103.1 |
RefSeqi | NP_001259941.1, NM_001273012.1 NP_608684.1, NM_134840.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0077770; FBpp0077450; FBgn0031428 FBtr0335462; FBpp0307439; FBgn0031428 |
GeneIDi | 33431 |
KEGGi | dme:Dmel_CG9886 |
UCSCi | CG9886-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AAF51252.1 AY061555 mRNA Translation: AAL29103.1 |
RefSeqi | NP_001259941.1, NM_001273012.1 NP_608684.1, NM_134840.3 |
3D structure databases
SMRi | Q9VQC4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7227.FBpp0077450 |
Proteomic databases
PaxDbi | Q9VQC4 |
Protocols and materials databases
DNASUi | 33431 |
Genome annotation databases
EnsemblMetazoai | FBtr0077770; FBpp0077450; FBgn0031428 FBtr0335462; FBpp0307439; FBgn0031428 |
GeneIDi | 33431 |
KEGGi | dme:Dmel_CG9886 |
UCSCi | CG9886-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0031428, CG9886 |
VEuPathDBi | VectorBase:FBgn0031428 |
Phylogenomic databases
eggNOGi | KOG3935, Eukaryota |
GeneTreei | ENSGT00390000014365 |
HOGENOMi | CLU_032279_0_0_1 |
InParanoidi | Q9VQC4 |
OMAi | ICGGEPV |
OrthoDBi | 1371490at2759 |
PhylomeDBi | Q9VQC4 |
Enzyme and pathway databases
Reactomei | R-DME-70350, Fructose catabolism |
Miscellaneous databases
BioGRID-ORCSi | 33431, 0 hits in 3 CRISPR screens |
GenomeRNAii | 33431 |
PROi | PR:Q9VQC4 |
Gene expression databases
Bgeei | FBgn0031428, Expressed in arthropod fat body and 40 other tissues |
ExpressionAtlasi | Q9VQC4, baseline and differential |
Genevisiblei | Q9VQC4, DM |
Family and domain databases
Gene3Di | 3.40.1480.10, 1 hit 3.40.50.10180, 1 hit |
InterProi | View protein in InterPro IPR037035, GK-like_C_sf IPR038614, GK_N_sf IPR007835, MOFRL IPR025286, MOFRL_assoc_dom IPR039760, MOFRL_protein |
PANTHERi | PTHR12227, PTHR12227, 1 hit |
Pfami | View protein in Pfam PF13660, DUF4147, 1 hit PF05161, MOFRL, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GLCTK_DROME | |
Accessioni | Q9VQC4Primary (citable) accession number: Q9VQC4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 15, 2007 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 126 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Drosophila
Drosophila: entries, gene names and cross-references to FlyBase - SIMILARITY comments
Index of protein domains and families