UniProtKB - Q9VNF5 (Q9VNF5_DROME)
Protein
3-oxoacyl-[acyl-carrier-protein] synthase
Gene
anon-WO0118547.367
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 187 | UniRule annotation | 1 |
GO - Molecular functioni
- 3-oxoacyl-[acyl-carrier-protein] synthase activity Source: GO_Central
GO - Biological processi
- fatty acid biosynthetic process Source: GO_Central
Keywordsi
Molecular function | AcyltransferaseImportedARBA annotation, Transferase |
Biological process | Fatty acid biosynthesisUniRule annotationARBA annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Names & Taxonomyi
Protein namesi | Recommended name: 3-oxoacyl-[acyl-carrier-protein] synthaseUniRule annotation |
Gene namesi | Name:anon-WO0118547.367Imported Synonyms:Dmel\CG12170Imported ORF Names:CG12170Imported, Dmel_CG12170Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0037356, CG12170 |
Expressioni
Gene expression databases
Bgeei | FBgn0037356, Expressed in capitellum (Drosophila) and 38 other tissues |
ExpressionAtlasi | Q9VNF5, baseline and differential |
Genevisiblei | Q9VNF5, DM |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 26 – 438 | PKS_KSInterPro annotationAdd BLAST | 413 |
Sequence similaritiesi
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.UniRule annotationARBA annotation
Phylogenomic databases
eggNOGi | KOG1394, Eukaryota |
GeneTreei | ENSGT00940000157768 |
HOGENOMi | CLU_000022_69_2_1 |
InParanoidi | Q9VNF5 |
OMAi | QIGHCLG |
OrthoDBi | 1014523at2759 |
PhylomeDBi | Q9VNF5 |
Family and domain databases
CDDi | cd00834, KAS_I_II, 1 hit |
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR017568, 3-oxoacyl-ACP_synth-2 IPR000794, Beta-ketoacyl_synthase IPR018201, Ketoacyl_synth_AS IPR014031, Ketoacyl_synth_C IPR014030, Ketoacyl_synth_N IPR020841, PKS_Beta-ketoAc_synthase_dom IPR016039, Thiolase-like |
PANTHERi | PTHR11712, PTHR11712, 1 hit |
Pfami | View protein in Pfam PF00109, ketoacyl-synt, 1 hit PF02801, Ketoacyl-synt_C, 1 hit |
PIRSFi | PIRSF000447, KAS_II, 1 hit |
SMARTi | View protein in SMART SM00825, PKS_KS, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
TIGRFAMsi | TIGR03150, fabF, 1 hit |
PROSITEi | View protein in PROSITE PS00606, B_KETOACYL_SYNTHASE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VNF5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRVLGKCTVL VRQTRSLSTP SGRRRVVVTG SGAVTPLGNN GPDSWRRILA
60 70 80 90 100
GESAISRLSA EFKGLPCQVA AQIPRENLQL DQHLTKSDIK LMSPATQLAV
110 120 130 140 150
LAAEEALSTG KLCPKQLSEE ELERFGVCVG MGMFDLAEVY GAWNQLQRGY
160 170 180 190 200
NRVSPFFVPR LLPSMACGHI SMRHGLRGPN HSVSTACATG AHALGDAMRF
210 220 230 240 250
IRSGDADLML AGSGEACIDP LSIAGFCRLR ALSTAFNDNP AVASRPFDKS
260 270 280 290 300
RDGFVMGEGA AVLLLEELEH ARARGAPILA EILGYGLSGD AYHITSPSDD
310 320 330 340 350
GAGATLAMKR AIQDAGIAPE DVTYVNAHAT STPTGDRIES HAIGRVFGAH
360 370 380 390 400
TPQVRVSSTK GAHGHLLGSS GNLEALFVVL ACANNKLPPS INIEHLDVDV
410 420 430
NVVTKATDWS ADQKRRVALK NSFGFGGTNA SLCIASYI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF51982.1 |
RefSeqi | NP_649565.1, NM_141308.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0078709; FBpp0078358; FBgn0037356 |
GeneIDi | 40692 |
KEGGi | dme:Dmel_CG12170 |
UCSCi | CG12170-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF51982.1 |
RefSeqi | NP_649565.1, NM_141308.3 |
3D structure databases
SMRi | Q9VNF5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7227.FBpp0078358 |
Proteomic databases
PaxDbi | Q9VNF5 |
PRIDEi | Q9VNF5 |
Genome annotation databases
EnsemblMetazoai | FBtr0078709; FBpp0078358; FBgn0037356 |
GeneIDi | 40692 |
KEGGi | dme:Dmel_CG12170 |
UCSCi | CG12170-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0037356, CG12170 |
Phylogenomic databases
eggNOGi | KOG1394, Eukaryota |
GeneTreei | ENSGT00940000157768 |
HOGENOMi | CLU_000022_69_2_1 |
InParanoidi | Q9VNF5 |
OMAi | QIGHCLG |
OrthoDBi | 1014523at2759 |
PhylomeDBi | Q9VNF5 |
Miscellaneous databases
BioGRID-ORCSi | 40692, 0 hits in 3 CRISPR screens |
GenomeRNAii | 40692 |
Gene expression databases
Bgeei | FBgn0037356, Expressed in capitellum (Drosophila) and 38 other tissues |
ExpressionAtlasi | Q9VNF5, baseline and differential |
Genevisiblei | Q9VNF5, DM |
Family and domain databases
CDDi | cd00834, KAS_I_II, 1 hit |
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR017568, 3-oxoacyl-ACP_synth-2 IPR000794, Beta-ketoacyl_synthase IPR018201, Ketoacyl_synth_AS IPR014031, Ketoacyl_synth_C IPR014030, Ketoacyl_synth_N IPR020841, PKS_Beta-ketoAc_synthase_dom IPR016039, Thiolase-like |
PANTHERi | PTHR11712, PTHR11712, 1 hit |
Pfami | View protein in Pfam PF00109, ketoacyl-synt, 1 hit PF02801, Ketoacyl-synt_C, 1 hit |
PIRSFi | PIRSF000447, KAS_II, 1 hit |
SMARTi | View protein in SMART SM00825, PKS_KS, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
TIGRFAMsi | TIGR03150, fabF, 1 hit |
PROSITEi | View protein in PROSITE PS00606, B_KETOACYL_SYNTHASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VNF5_DROME | |
Accessioni | Q9VNF5Primary (citable) accession number: Q9VNF5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 10, 2021 | |
This is version 157 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |