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Protein

60S ribosomal protein L37a

Gene

RpL37A

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri39 – 60C4-typeAdd BLAST22

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L37a
Gene namesi
Name:RpL37A
ORF Names:CG5827
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0261608 RpL37A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001398272 – 9260S ribosomal protein L37aAdd BLAST91

Proteomic databases

PaxDbiQ9VMU4
PRIDEiQ9VMU4

Expressioni

Gene expression databases

BgeeiFBgn0261608
ExpressionAtlasiQ9VMU4 differential
GenevisibleiQ9VMU4 DM

Interactioni

Protein-protein interaction databases

BioGridi69275, 5 interactors
IntActiQ9VMU4, 4 interactors
STRINGi7227.FBpp0291726

Structurei

3D structure databases

ProteinModelPortaliQ9VMU4
SMRiQ9VMU4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri39 – 60C4-typeAdd BLAST22

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG0402 Eukaryota
COG1997 LUCA
GeneTreeiENSGT00390000016988
InParanoidiQ9VMU4
KOiK02921
OMAiISTGIWQ
OrthoDBiEOG091G107U
PhylomeDBiQ9VMU4

Family and domain databases

Gene3Di2.20.25.30, 1 hit
HAMAPiMF_00327 Ribosomal_L37Ae, 1 hit
InterProiView protein in InterPro
IPR002674 Ribosomal_L37ae
IPR011331 Ribosomal_L37ae/L37e
IPR011332 Ribosomal_zn-bd
PANTHERiPTHR43931 PTHR43931, 1 hit
PfamiView protein in Pfam
PF01780 Ribosomal_L37ae, 1 hit
SUPFAMiSSF57829 SSF57829, 1 hit
TIGRFAMsiTIGR00280 eL43_euk_arch, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9VMU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRTKKVGI VGKYGTRYGA SLRKMVKKME ITQHSKYTCS FCGKDSMKRA
60 70 80 90
VVGIWSCKRC KRTVAGGAWV YSTTAAASVR SAVRRLRETK EQ
Length:92
Mass (Da):10,311
Last modified:January 23, 2007 - v3
Checksum:iF8D85A34503C1FC6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF52217.1
AE014134 Genomic DNA Translation: AAN10530.1
AY071189 mRNA Translation: AAL48811.1
AY071725 mRNA Translation: AAL49347.1
RefSeqiNP_001188691.1, NM_001201762.1
NP_524781.1, NM_080042.4
NP_723060.1, NM_164628.3
UniGeneiDm.1819

Genome annotation databases

EnsemblMetazoaiFBtr0079016; FBpp0078655; FBgn0261608
FBtr0079017; FBpp0078656; FBgn0261608
FBtr0302570; FBpp0291726; FBgn0261608
GeneIDi44783
KEGGidme:Dmel_CG5827

Similar proteinsi

Entry informationi

Entry nameiRL37A_DROME
AccessioniPrimary (citable) accession number: Q9VMU4
Secondary accession number(s): A4V081
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: January 23, 2007
Last modified: July 18, 2018
This is version 128 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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