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Protein
Submitted name:

Blue cheese

Gene

bchs

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3423 – 3483FYVE-typePROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLinkiQ9VML2

Names & Taxonomyi

Protein namesi
Submitted name:
Blue cheeseImported
Gene namesi
Name:bchsImported
Synonyms:AlfyImported, alfyImported, BcDNA:SD12984Imported, bchdImported, BchsImported, Beach1Imported, CG14001Imported, CG9011Imported, DBEACH1Imported, Dmel\CG14001Imported, EP2299Imported
ORF Names:CG14001Imported, Dmel_CG14001Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0043362 bchs

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiQ9VML2
PRIDEiQ9VML2

Expressioni

Gene expression databases

BgeeiFBgn0043362 Expressed in 26 organ(s), highest expression level in brain
ExpressionAtlasiQ9VML2 baseline and differential
GenevisibleiQ9VML2 DM

Interactioni

Protein-protein interaction databases

IntActiQ9VML2, 1 interactor
STRINGi7227.FBpp0078775

Structurei

3D structure databases

ProteinModelPortaliQ9VML2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2466 – 2597BEACH-type PHInterPro annotationAdd BLAST132
Domaini2625 – 2918BEACHInterPro annotationAdd BLAST294
Domaini3036 – 3202WD_REPEATS_REGIONInterPro annotationAdd BLAST167
Repeati3068 – 3109WDPROSITE-ProRule annotationAdd BLAST42
Repeati3178 – 3195WDPROSITE-ProRule annotationAdd BLAST18
Domaini3423 – 3483FYVE-typeInterPro annotationAdd BLAST61

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3423 – 3483FYVE-typePROSITE-ProRule annotationAdd BLAST61

Keywords - Domaini

WD repeatPROSITE-ProRule annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1786 Eukaryota
KOG1788 Eukaryota
ENOG410XNQC LUCA
GeneTreeiENSGT00760000119083
InParanoidiQ9VML2
KOiK22262
OMAiCEKFVVM
OrthoDBiEOG091G002Q
PhylomeDBiQ9VML2

Family and domain databases

CDDicd06071 Beach, 1 hit
cd01201 PH_BEACH, 1 hit
Gene3Di1.10.1540.10, 1 hit
2.130.10.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR000409 BEACH_dom
IPR036372 BEACH_dom_sf
IPR023362 PH-BEACH_dom
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF02138 Beach, 1 hit
PF01363 FYVE, 1 hit
PF14844 PH_BEACH, 1 hit
PF00400 WD40, 1 hit
SMARTiView protein in SMART
SM01026 Beach, 1 hit
SM00064 FYVE, 1 hit
SM00320 WD40, 5 hits
SUPFAMiSSF48371 SSF48371, 3 hits
SSF50978 SSF50978, 2 hits
SSF57903 SSF57903, 1 hit
SSF81837 SSF81837, 1 hit
PROSITEiView protein in PROSITE
PS50197 BEACH, 1 hit
PS51783 PH_BEACH, 1 hit
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit
PS50178 ZF_FYVE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VML2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNVMRKLRGA ASAGSVSGSS SGTSTANNSS PGSSRTDAGA PTAANGRNAE
60 70 80 90 100
EALMDARVQV SLTTLKKLFN EYTHPREPLS EQERDDKLYE MLPLFCKVFS
110 120 130 140 150
SCPSNDMSEK FWDVVAFCQQ VSRLMVSEIR KRASNQSTEA ASIAIVKFLE
160 170 180 190 200
VETTEETSSG WMLLATLNLL ANGDVSLIQV MTAAAVPSTL VKCLYLFFDL
210 220 230 240 250
PIVEDDEPSA DGGAVSEFNA HERRTLLQKV FVQLLVKLCS YPYPAEELAR
260 270 280 290 300
MDDLTLLFSA ITSPCPIHNI VWRKNAAEIL TTISRNGLTD AVVSYIHSKG
310 320 330 340 350
CMALCVDNMQ RLTFGNPLEI VEMFVTVFCF LKDSSQVSQI LMDDFRASQG
360 370 380 390 400
YVFLSDFLLK FDNNRSQSLE IQAAIRNLVL MISSLCMCGF YELRPPASQF
410 420 430 440 450
NTAFKLQNFQ LPQATSRETC VRNVYAFQVL QNVFLKSTTP ALCCTILDAI
460 470 480 490 500
SRVYHSENAN YFILESEQTL SSFAERIHMK SPQIQEKFYD LLEFIVFQLN
510 520 530 540 550
FVPCKELISL SLLLKHNQST SCSILCLKTL LNILRHNAVF KDVYREVGIL
560 570 580 590 600
EIFVGCLTRY AAHVQKITKG DESVVVELEN ESEEELFDTL GKHVLEALTM
610 620 630 640 650
LLGGGASNNA QLFREYGGAK CVHELVKFKH CRPQALGIVR ELILSAGGDD
660 670 680 690 700
DMLHILSLMH SVSPLQVEFK IQILNMLLGC LKDSHRTRTV FRKVGGFVYV
710 720 730 740 750
TSVFVSLDGS MALPQPDIPQ QDLILLLQIV FQTLATAMRF EPANAKFFHQ
760 770 780 790 800
EISSSSLCDT LRLLGCFGGS SALQDYTGTY EPQQSLLKYY HEIFSGDILS
810 820 830 840 850
VSFSEDVPYP LSYVCIVFRL LYSIALDNFE APNLSGIITL FSDPPTTLRS
860 870 880 890 900
PSKELAPPVH PSQLNLTQPS PEPRIVHPGV VLCMLQLLPA VEYDMAPLQA
910 920 930 940 950
VQLQVYLSEI IKSLVRSERN QQIMCDHGLA EKLLKLTRRA LAEESHPLHV
960 970 980 990 1000
PMQYILERLA AQALQPTELR QFLRLGEPLS CADIDLQQPY KLGGPVPLTR
1010 1020 1030 1040 1050
IKTLVSMTTP RDFRAHGSST LPPFVELDMS AEGFGCLYLP SLAPQATATA
1060 1070 1080 1090 1100
GGTIDANSIG GIGAGDRIFP PQTGLTYSTW FCVEKFSDPK TDPHCVRLLT
1110 1120 1130 1140 1150
LVRTIHNPRE ENLACLSILL SARDKAIVVS TQETLVTPRK SIGDWEPEGS
1160 1170 1180 1190 1200
DDGIARIWCP DLLHEGQWHN LVVVLNRAVL KNSSLFLYLD GVPMHTQKLH
1210 1220 1230 1240 1250
YIAQHPAAGN ASLTSPTQIF GYIGTPPIWR RYSRLCWKQG VCHLIEDVLT
1260 1270 1280 1290 1300
QQTVQTIYQL GPHYMGSLQA PQLGKQSESL APLVPEDRVL LGLNAKAVSK
1310 1320 1330 1340 1350
LTLVKIRKVY SRADNKSIAK QLNMNSHENA TPIKILHNSA GHLAGAGRSL
1360 1370 1380 1390 1400
GGVVVGYLGV RVFSPHPVSA MIDTVGGCNV LLGIIAMAQD VESLYAGVKA
1410 1420 1430 1440 1450
LTCVVRSNRA AQAEMDRKRC YQTLGMFFKK KKHLLNSHIL HLTFGLVGTV
1460 1470 1480 1490 1500
NSGQDMSAIP NVTAFQDLLC DLEIWHNAPN GLLRSLLEHL LELVVESSDK
1510 1520 1530 1540 1550
KQNVKIMRDL QLLVKLLHII TQIQDHSTRE ILFSLLETLL GGQPRHTDLL
1560 1570 1580 1590 1600
LFGQYVAAKL PHAHSGGLER AVLLPSMKNP AEDQDGGVAQ NIYLRNRCLS
1610 1620 1630 1640 1650
LLHGLLFTPR NTVNYVICDD ISKTLGMDWL LLFMQPHVHF TTVIIAVRIL
1660 1670 1680 1690 1700
VVICANESFL VRFRDATHNG GYLRFTEMVS QRKMLGLGAQ QLNQRPTNGT
1710 1720 1730 1740 1750
GTVIVATPQN TIQHLPTQIA GEVRAAALNI PGFQLLEWLM NHHLDVPELY
1760 1770 1780 1790 1800
FLITALIMGQ PVKVLATEHT KFDLDRVWSF LWGAPVSANT QLPKLNICPE
1810 1820 1830 1840 1850
GVCVLLAMVR GIVHGGECAP WLHSHPETII QLLFSLYQNL TDFAPVMMTG
1860 1870 1880 1890 1900
DVVTSLVAVL FPLASRPADS EPNSGASTPT DDTGSSFALP PPETLHGAPQ
1910 1920 1930 1940 1950
PKLTAHPVCN CIIDFLRVIV VDSLGLNMQG KPTPVIDLVL DAAPESAELP
1960 1970 1980 1990 2000
LQVQYQTQII IALMDHLLAA DVLVGEQAAL PLVPLLQSQM QYIAPNVFYL
2010 2020 2030 2040 2050
TARIVDKLWQ GCLARNPHDI FDFVIKLIVQ AKRRSSSLSL EHLHHSLNRS
2060 2070 2080 2090 2100
ILFLLSRPTD DSRADQMSVL EALHKIIQHR LLIFGAGNHE LEFIGCLTYC
2110 2120 2130 2140 2150
LLQLTADMKI ILEPATSRNT TWHVNPQTET AEPKDEDLNQ LQGRNLIVGA
2160 2170 2180 2190 2200
AFRVWEELYV CKKPAIEEVF KVSLTSPPPN SKAPDLQTTR EQVMELASKL
2210 2220 2230 2240 2250
WFNYVEAERK ATYRAPWELH TQIQSKIQKV TGGLSRLTSR TKTKKEELVR
2260 2270 2280 2290 2300
TRSTLTREAA YESTGIHVQL IKDLLDLRAK QYQQMLQHTQ RYVYQDWVQS
2310 2320 2330 2340 2350
EMELTRERGL WGPTGSCSLD KWILDTTEGP HRMRKKTMRN DVFYLHYPYR
2360 2370 2380 2390 2400
PELELADNRQ LKYKVASSLD SKTYALHGPQ QPRILAEAGE HHAMQQQSSL
2410 2420 2430 2440 2450
EAVQSHRLET SSSTSTPPPM VLPKLVGHGS TPCPQESVDG NAPEDDEEEE
2460 2470 2480 2490 2500
DTSMTSDNET FLRLLEEQEK ISFMFRCARV QGLDTFEGLL LFGKEHCYIV
2510 2520 2530 2540 2550
DGFTLLKNRE IRDIDTLPPG AYEPIIPNSG GTSSTTSRAV SHKLRQCSKF
2560 2570 2580 2590 2600
AYEEIREVHK RRYLLQPIAL EVFSEDGRNY LLSFPRKVRN KVNQRFLALA
2610 2620 2630 2640 2650
TALNDNAQQS VAGQKRTASV EQTAGIFSGL IGETSVTQRW VRGEISNFQY
2660 2670 2680 2690 2700
LMHLNTLAGR SYNDLMQYPV FPWILADYDS EELDLTNPKT FRDFSRPMGA
2710 2720 2730 2740 2750
QAEERLEQFQ KRFKEWDDPH GETPPYHYGT HYSSAMIVCS YLVRLEPFSQ
2760 2770 2780 2790 2800
PFLKLQGGHF DLADRMFHSI KEAWLSASKL NMADVKELIP EFFYLPEFLS
2810 2820 2830 2840 2850
NFNNFDLGTK QNGETLNHVI LPPWAKHDPR EFIRLHRSAL ECDYVSQHLH
2860 2870 2880 2890 2900
LWIDLIFGCK QQGPAAVDAV NVFHHLFYEG NVDIYNIDDP LKKNATIGFI
2910 2920 2930 2940 2950
NNFGQIPKQL FKKAHPAKKM GGSRHSALID PTSLIQGNST VLQTDRLFFH
2960 2970 2980 2990 3000
NLDNLKPSLQ PIKELKGPVG QILQPDKTVF AVEQNKVMMP PSYTKYIAWG
3010 3020 3030 3040 3050
FADHSLRIGL YDTDRASFVS EASAQNSGEI LTCACPNAKM IVTAGTSSVV
3060 3070 3080 3090 3100
TIWKFDANRK SLAVKHSLHG HTDAVTCLAA SAAYNVIVSG SRDGTAIVWD
3110 3120 3130 3140 3150
MTRFTFVRQL RGHAGVVAAV SINELTGDIA TCSATWLHVW SINGDALAMV
3160 3170 3180 3190 3200
NTCVGSADRM QQILCVAFSQ IREWDQQNVI ITGSTDGVVR MWSLEHTQVP
3210 3220 3230 3240 3250
IDRKLKRGTE VSSQDKPDTV SLEGKDNKDD KMSLMKQIKS LSQSEEEMEI
3260 3270 3280 3290 3300
VKSASESSIS EASQHSHGSS KSAEAGPKAE VQGERRKSSI SGAKSLHEMK
3310 3320 3330 3340 3350
SATVEGQGSS YDPKSNEDEH AIRPSKSDTS LTDGFVVIDN DRHKGDQILR
3360 3370 3380 3390 3400
KGFRWQRQLM FRSKLTMHTA YDRKDNAEPA SITALTVSKD HKILYVGDAR
3410 3420 3430 3440 3450
GRIFSWSVTE QPGRGVADHW LKDEGADQCV KCHVKFTLYE RKHHCRNCGQ
3460 3470 3480
VFCNKCSRFE SEISRLRILK PVRVCQACYS QLRTNSLDN
Length:3,489
Mass (Da):389,825
Last modified:July 5, 2004 - v4
Checksum:iF4DD29D2D017EE20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF52302.4
RefSeqiNP_608968.2, NM_135124.2
UniGeneiDm.12933

Genome annotation databases

EnsemblMetazoaiFBtr0079144; FBpp0078775; FBgn0043362
GeneIDi33819
KEGGidme:Dmel_CG14001
UCSCiCG14001-RA d. melanogaster

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF52302.4
RefSeqiNP_608968.2, NM_135124.2
UniGeneiDm.12933

3D structure databases

ProteinModelPortaliQ9VML2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9VML2, 1 interactor
STRINGi7227.FBpp0078775

Proteomic databases

PaxDbiQ9VML2
PRIDEiQ9VML2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0079144; FBpp0078775; FBgn0043362
GeneIDi33819
KEGGidme:Dmel_CG14001
UCSCiCG14001-RA d. melanogaster

Organism-specific databases

CTDi33819
FlyBaseiFBgn0043362 bchs

Phylogenomic databases

eggNOGiKOG1786 Eukaryota
KOG1788 Eukaryota
ENOG410XNQC LUCA
GeneTreeiENSGT00760000119083
InParanoidiQ9VML2
KOiK22262
OMAiCEKFVVM
OrthoDBiEOG091G002Q
PhylomeDBiQ9VML2

Enzyme and pathway databases

SignaLinkiQ9VML2

Miscellaneous databases

GenomeRNAii33819

Gene expression databases

BgeeiFBgn0043362 Expressed in 26 organ(s), highest expression level in brain
ExpressionAtlasiQ9VML2 baseline and differential
GenevisibleiQ9VML2 DM

Family and domain databases

CDDicd06071 Beach, 1 hit
cd01201 PH_BEACH, 1 hit
Gene3Di1.10.1540.10, 1 hit
2.130.10.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR000409 BEACH_dom
IPR036372 BEACH_dom_sf
IPR023362 PH-BEACH_dom
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF02138 Beach, 1 hit
PF01363 FYVE, 1 hit
PF14844 PH_BEACH, 1 hit
PF00400 WD40, 1 hit
SMARTiView protein in SMART
SM01026 Beach, 1 hit
SM00064 FYVE, 1 hit
SM00320 WD40, 5 hits
SUPFAMiSSF48371 SSF48371, 3 hits
SSF50978 SSF50978, 2 hits
SSF57903 SSF57903, 1 hit
SSF81837 SSF81837, 1 hit
PROSITEiView protein in PROSITE
PS50197 BEACH, 1 hit
PS51783 PH_BEACH, 1 hit
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit
PS50178 ZF_FYVE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VML2_DROME
AccessioniPrimary (citable) accession number: Q9VML2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: July 5, 2004
Last modified: September 12, 2018
This is version 159 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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