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Entry version 130 (12 Aug 2020)
Sequence version 2 (01 Mar 2001)
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Protein

Tiggrin

Gene

Tig

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a ligand for integrin alpha-PS2/beta-PS. Required in larvae for proper muscle structure and function. Involved in the regulation of cell adhesion during wing development.4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • integrin binding Source: FlyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TiggrinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TigImported
ORF Names:CG11527
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0011722, Tig

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Pupal lethal with about 1% escapers. In mutant larvae, muscles 6 and 7 appear stringy and not anchored to other muscles or the epidermis, often these muscles are missing or unrecognizable. Sites where muscles 3, 4, 5, 8 and 16 come together are rarely recognizable and large gaps between muscles 9 and 10 can be observed. Muscle contraction waves that transverse the length of the larvae and are responsible for locomotion are much slower in mutant larvae. Mutant pupae are longer than wild type pupae. Mutant adult flies present elongated abdomen and wings with altered shapes and sizes.2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi1989 – 1991RGD → LGA: Partially rescues muscle function and structure defects in the null mutant. Fails to interact with alpha-PS2/beta-PS. 1 Publication3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 181 PublicationAdd BLAST18
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500014415219 – 2188Tiggrin1 PublicationAdd BLAST2170

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

O-glycosylation by pgant3 is required for proper secretion and localization to the basal cell layer interface during wing development.2 Publications

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VMD9

PRoteomics IDEntifications database

More...
PRIDEi
Q9VMD9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In embryos, expressed in the apodemes (muscle attachment sites) of the major longitudinal muscles 4, 6, 7, 12 and 13 and the wide dorsal oblique muscles 9 and 10, in hemocytes, in fat body cells, in basement membranes surrounding the gut and in the commissures of the ventral nerve cord. Expressed in larval imaginal wing disk and in pupal wing. In adult flies, expressed in the jump muscle (at protein level).5 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed throughout embryogenesis; first appears at 8-10 hours. Detected in larval and pupal stages (at protein level). Transcripts are first detected at 6-8 hours of development, expression peaks at 12-14 hours and then declines by the end of embryogenesis.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0011722, Expressed in arthropod fat body and 33 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VMD9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VMD9, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
60053, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VMD9, 12 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0078905

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili570 – 635Sequence analysisAdd BLAST66
Coiled coili1009 – 1050Sequence analysisAdd BLAST42
Coiled coili1312 – 1343Sequence analysisAdd BLAST32
Coiled coili1613 – 1641Sequence analysisAdd BLAST29

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1989 – 1991Cell attachment site2 Publications3

Keywords - Domaini

Coiled coil, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S4BN, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_231371_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VMD9

Identification of Orthologs from Complete Genome Data

More...
OMAi
QNKQWSA

Database of Orthologous Groups

More...
OrthoDBi
16764at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VMD9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016084, Haem_Oase-like_multi-hlx

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48613, SSF48613, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VMD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRALGGITLL LAVAICQGYE TYQRSSFRSS SSSSYGGGQT VPQLNSFASA
60 70 80 90 100
HFNEVRELAN QLKQKFNVLS QGSTNFAYTS PWSASILDLS GKSTLQLDQL
110 120 130 140 150
SSEISRQLVQ DMREGITNYH TIAQPNFFEA KAAELLERYS GAESASLQQT
160 170 180 190 200
VGLGPYQPVD LSGFDEVKNY AYPAEVKVID GKTYVVHRNC TEATKLSDYG
210 220 230 240 250
SSGQLNSGFL GHQQTSLPLS STTTTITRKK TIHDWVRENM EPSVVGYNSV
260 270 280 290 300
VKLDGQLRNS ALNQMVPLSP GSNVVIHRFN KTITTNPDGT SSVGGSEWQQ
310 320 330 340 350
RWQDGKLVYD HQQPFGQSTI PRDEQWKREE RERLFWYLTT PQRLDDWQQQ
360 370 380 390 400
QEERLLGVVQ RYQVSLPVLK EFHRRELARY EALLGQYQSR VQDTSSWQRQ
410 420 430 440 450
ERGRLDWLIH QNGFTVQDIE RWQNENARKL AEAARQHGIS QNQLQQFQRE
460 470 480 490 500
ELQRLYVHFN QVNESLAPQV PSVPQTTYNY QSSSSLTEDN TKEQQRLEEL
510 520 530 540 550
IRQHNATIAA LQNSIKTDQQ RLKNLSIKYQ GDMQSQTQWL RGEVARIGDL
560 570 580 590 600
IKEQNEQVSK ITAWQSSERS RLENILLQHR GSVEEVQQRI NMDRNYLQNL
610 620 630 640 650
ATKYQVSVEE LEKWQKEELE RLQVRGQQQL EEHIKDWQIS VSSNLRDIAT
660 670 680 690 700
QNKLTIDEFQ NYIINDRSHL EEMARLYKVK VEEIEQWIKS ELKKFQSEGL
710 720 730 740 750
LKGVEQELIQ WQQKERERLQ AIVQQNSLTV EQLEVRIKND QDHFFKLADK
760 770 780 790 800
YKINVEDIQD WLKKELLRLQ SEGLVKAETL KEWQQQERAQ ISLLVQQNKY
810 820 830 840 850
SLDEFERKML ADRARLQELS NTYNVKVSEI EQWIKSEGDR LQHEGQLRME
860 870 880 890 900
SQLNNWQKIE RQRLLDLINK NNLSIEEIES KISKDQTHLY SLAQQHQVRV
910 920 930 940 950
EEIEQWIRQQ IQKLQDQGLI EMQKLKNWQL EWRGNLTNMV QDRDFTVEEF
960 970 980 990 1000
HKWLLKDREQ LQSLAMQHNV QIEEIEQFVK KEEQRFIGMG LLKPSEKLTN
1010 1020 1030 1040 1050
WQEVERLHLK NLAQQQYKST EQLEARLRQD RELLERLARQ YSVQVEEIES
1060 1070 1080 1090 1100
WMKQELARMR DEGQLQIDNL TSWQLAERER LEALIKQNKQ WSAEELRAEL
1110 1120 1130 1140 1150
EKDREHMQTM AFQYHTSVEE IEKWLQSEIE RLKQQGKLNI EQLTAWQRTE
1160 1170 1180 1190 1200
QQRILSLLQQ HSNITLEQFQ AKVHNDRRFL MNLAEQHHVH IEEVDNYVKQ
1210 1220 1230 1240 1250
VIEDLRKNGQ FEIEQLQTWQ RVERDYIKSL ISEYKNSLST AEYEEKLLAD
1260 1270 1280 1290 1300
RAHLKHLADQ YRINVEQIEE WMIAELKRLR GSTEETLKSL SAWQVSELER
1310 1320 1330 1340 1350
LQNLVKQQNH LTFVEFEMEL NQERDRLQKL ANQYSVNVVE IEEWLRQQLI
1360 1370 1380 1390 1400
NLRTTGQAKV ENLSKWQVEE QQRLIEMLLK KQQEMPYEQV ERELTQDHAR
1410 1420 1430 1440 1450
LQSLSQTHHV DIDHVDHWLR EELRRLQSSG LVQIEQQTQW QQKISNGFNN
1460 1470 1480 1490 1500
WLEQQRNGAS YQDFVDFLKR DKQRMDGIAT DYHVTVEQVE KWVQKEAARL
1510 1520 1530 1540 1550
SLIGVIERPE NNLKYEDISN IWVGDQTDSW KNELVTRLRS VTRQRPFTRQ
1560 1570 1580 1590 1600
EFESYLIRNK PIFEQIARQY HVTIEDIHLW LDQSAKNEGL VTTEWQAKER
1610 1620 1630 1640 1650
LHIDNLINQQ LRKQQRWTIE ELELRLNNDQ KHLQDAVAQY HVTVEELKVW
1660 1670 1680 1690 1700
YKDELNRLLE QRRIDRGSGI SWQNIESQRI YLAIVNNPGI SRQALENRLF
1710 1720 1730 1740 1750
RDVHVRASQY QITVEELRQF ILSQLRRFSD MGLIVDNGRQ ANNWHDQERK
1760 1770 1780 1790 1800
RLREVVKGVV ITEQELLDFI SQDTSFQTQL AQSYQVGLEQ LAPVQRIFIG
1810 1820 1830 1840 1850
NLAREQLLEQ RRLNHLTTWQ QRERDRLYEF IGNQNMTQTE LKTWQIQDSK
1860 1870 1880 1890 1900
LLAEFAKRYE ISVQQLSDWQ KKELARINQL ARYYGMSQSD LQQFREGELR
1910 1920 1930 1940 1950
QLAYINHRQL LSAAEAQKWE KRHQWTLSRL QSRYGKFGQE LVAWRRTLYL
1960 1970 1980 1990 2000
LSQGLIDLPA DSGSNGGYVV DAGSTNATAV YKPIFSKDRG DQPPHTYDES
2010 2020 2030 2040 2050
FVEGDEPGLE GETARPRPPN PAPIVSTPKP PLPYSRGGPS GGFEYRRQDY
2060 2070 2080 2090 2100
TFNVPVGSAS ASASGGPTGS SASASASLGK WNRASGDEPL QQEVDLGQQQ
2110 2120 2130 2140 2150
QIEELGWNEK LEDLGQQTQV EDTDWNQQAE DLGQQQQVQV EDDLHFDQTQ
2160 2170 2180
GHSSSSNSRS QPLQQATKVE VEATSEPSFW EKLKEKLG
Length:2,188
Mass (Da):257,446
Last modified:March 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFFD4715696C33E9E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X2JDD7X2JDD7_DROME
Tiggrin, isoform B
Tig CT36389, Dmel\CG11527, TIG, tig, CG11527
2,188Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ23578 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti7I → V in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti77A → G in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti381E → Q in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti869N → S in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti2157 – 2158Missing in AAA56998 (PubMed:7924982).Curated2
Sequence conflicti2185E → G in AAA56998 (PubMed:7924982).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U09506 mRNA Translation: AAA56998.1
AE014134 Genomic DNA Translation: AAF52380.2
BT010260 mRNA Translation: AAQ23578.1 Frameshift.

NCBI Reference Sequences

More...
RefSeqi
NP_001285670.1, NM_001298741.1
NP_477033.1, NM_057685.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0079275; FBpp0078905; FBgn0011722
FBtr0343152; FBpp0309850; FBgn0011722

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
33896

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG11527

UCSC genome browser

More...
UCSCi
CG11527-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U09506 mRNA Translation: AAA56998.1
AE014134 Genomic DNA Translation: AAF52380.2
BT010260 mRNA Translation: AAQ23578.1 Frameshift.
RefSeqiNP_001285670.1, NM_001298741.1
NP_477033.1, NM_057685.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi60053, 3 interactors
IntActiQ9VMD9, 12 interactors
STRINGi7227.FBpp0078905

Proteomic databases

PaxDbiQ9VMD9
PRIDEiQ9VMD9

Genome annotation databases

EnsemblMetazoaiFBtr0079275; FBpp0078905; FBgn0011722
FBtr0343152; FBpp0309850; FBgn0011722
GeneIDi33896
KEGGidme:Dmel_CG11527
UCSCiCG11527-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
33896
FlyBaseiFBgn0011722, Tig

Phylogenomic databases

eggNOGiENOG502S4BN, Eukaryota
HOGENOMiCLU_231371_0_0_1
InParanoidiQ9VMD9
OMAiQNKQWSA
OrthoDBi16764at2759
PhylomeDBiQ9VMD9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
33896, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
33896

Protein Ontology

More...
PROi
PR:Q9VMD9

Gene expression databases

BgeeiFBgn0011722, Expressed in arthropod fat body and 33 other tissues
ExpressionAtlasiQ9VMD9, baseline and differential
GenevisibleiQ9VMD9, DM

Family and domain databases

InterProiView protein in InterPro
IPR016084, Haem_Oase-like_multi-hlx
SUPFAMiSSF48613, SSF48613, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTIG_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VMD9
Secondary accession number(s): Q23984, Q6NR23
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 16, 2013
Last sequence update: March 1, 2001
Last modified: August 12, 2020
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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