Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q9VMD9 (TIG_DROME)

Entry version 131 (07 Apr 2021)
Sequence version 2 (01 Mar 2001)
Previous versions | rss
Add a publicationFeedback
Protein

Tiggrin

Gene

Tig

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a ligand for integrin alpha-PS2/beta-PS. Required in larvae for proper muscle structure and function. Involved in the regulation of cell adhesion during wing development.4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • integrin binding Source: FlyBase
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TiggrinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TigImported
ORF Names:CG11527
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0011722, Tig

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Pupal lethal with about 1% escapers. In mutant larvae, muscles 6 and 7 appear stringy and not anchored to other muscles or the epidermis, often these muscles are missing or unrecognizable. Sites where muscles 3, 4, 5, 8 and 16 come together are rarely recognizable and large gaps between muscles 9 and 10 can be observed. Muscle contraction waves that transverse the length of the larvae and are responsible for locomotion are much slower in mutant larvae. Mutant pupae are longer than wild type pupae. Mutant adult flies present elongated abdomen and wings with altered shapes and sizes.2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi1989 – 1991RGD → LGA: Partially rescues muscle function and structure defects in the null mutant. Fails to interact with alpha-PS2/beta-PS. 1 Publication3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 181 PublicationAdd BLAST18
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500014415219 – 2188Tiggrin1 PublicationAdd BLAST2170

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

O-glycosylation by pgant3 is required for proper secretion and localization to the basal cell layer interface during wing development.2 Publications

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9VMD9

PRoteomics IDEntifications database

More...PRIDEi		Q9VMD9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In embryos, expressed in the apodemes (muscle attachment sites) of the major longitudinal muscles 4, 6, 7, 12 and 13 and the wide dorsal oblique muscles 9 and 10, in hemocytes, in fat body cells, in basement membranes surrounding the gut and in the commissures of the ventral nerve cord. Expressed in larval imaginal wing disk and in pupal wing. In adult flies, expressed in the jump muscle (at protein level).5 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed throughout embryogenesis; first appears at 8-10 hours. Detected in larval and pupal stages (at protein level). Transcripts are first detected at 6-8 hours of development, expression peaks at 12-14 hours and then declines by the end of embryogenesis.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0011722, Expressed in arthropod fat body and 33 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9VMD9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9VMD9, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		60053, 4 interactors

Protein interaction database and analysis system

More...IntActi		Q9VMD9, 12 interactors

STRING: functional protein association networks

More...STRINGi		7227.FBpp0078905

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9VMD9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili570 – 635Sequence analysisAdd BLAST66
Coiled coili1009 – 1050Sequence analysisAdd BLAST42
Coiled coili1312 – 1343Sequence analysisAdd BLAST32
Coiled coili1613 – 1641Sequence analysisAdd BLAST29

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1989 – 1991Cell attachment site2 Publications3

Keywords - Domaini

Coiled coil, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502S4BN, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_231371_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9VMD9

Identification of Orthologs from Complete Genome Data

More...OMAi		QNKQWSA

Database of Orthologous Groups

More...OrthoDBi		16764at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9VMD9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016084, Haem_Oase-like_multi-hlx

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48613, SSF48613, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VMD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRALGGITLL LAVAICQGYE TYQRSSFRSS SSSSYGGGQT VPQLNSFASA 
        60         70         80         90        100
HFNEVRELAN QLKQKFNVLS QGSTNFAYTS PWSASILDLS GKSTLQLDQL 
       110        120        130        140        150
SSEISRQLVQ DMREGITNYH TIAQPNFFEA KAAELLERYS GAESASLQQT 
       160        170        180        190        200
VGLGPYQPVD LSGFDEVKNY AYPAEVKVID GKTYVVHRNC TEATKLSDYG 
       210        220        230        240        250
SSGQLNSGFL GHQQTSLPLS STTTTITRKK TIHDWVRENM EPSVVGYNSV 
       260        270        280        290        300
VKLDGQLRNS ALNQMVPLSP GSNVVIHRFN KTITTNPDGT SSVGGSEWQQ 
       310        320        330        340        350
RWQDGKLVYD HQQPFGQSTI PRDEQWKREE RERLFWYLTT PQRLDDWQQQ 
       360        370        380        390        400
QEERLLGVVQ RYQVSLPVLK EFHRRELARY EALLGQYQSR VQDTSSWQRQ 
       410        420        430        440        450
ERGRLDWLIH QNGFTVQDIE RWQNENARKL AEAARQHGIS QNQLQQFQRE 
       460        470        480        490        500
ELQRLYVHFN QVNESLAPQV PSVPQTTYNY QSSSSLTEDN TKEQQRLEEL 
       510        520        530        540        550
IRQHNATIAA LQNSIKTDQQ RLKNLSIKYQ GDMQSQTQWL RGEVARIGDL 
       560        570        580        590        600
IKEQNEQVSK ITAWQSSERS RLENILLQHR GSVEEVQQRI NMDRNYLQNL 
       610        620        630        640        650
ATKYQVSVEE LEKWQKEELE RLQVRGQQQL EEHIKDWQIS VSSNLRDIAT 
       660        670        680        690        700
QNKLTIDEFQ NYIINDRSHL EEMARLYKVK VEEIEQWIKS ELKKFQSEGL 
       710        720        730        740        750
LKGVEQELIQ WQQKERERLQ AIVQQNSLTV EQLEVRIKND QDHFFKLADK 
       760        770        780        790        800
YKINVEDIQD WLKKELLRLQ SEGLVKAETL KEWQQQERAQ ISLLVQQNKY 
       810        820        830        840        850
SLDEFERKML ADRARLQELS NTYNVKVSEI EQWIKSEGDR LQHEGQLRME 
       860        870        880        890        900
SQLNNWQKIE RQRLLDLINK NNLSIEEIES KISKDQTHLY SLAQQHQVRV 
       910        920        930        940        950
EEIEQWIRQQ IQKLQDQGLI EMQKLKNWQL EWRGNLTNMV QDRDFTVEEF 
       960        970        980        990       1000
HKWLLKDREQ LQSLAMQHNV QIEEIEQFVK KEEQRFIGMG LLKPSEKLTN 
      1010       1020       1030       1040       1050
WQEVERLHLK NLAQQQYKST EQLEARLRQD RELLERLARQ YSVQVEEIES 
      1060       1070       1080       1090       1100
WMKQELARMR DEGQLQIDNL TSWQLAERER LEALIKQNKQ WSAEELRAEL 
      1110       1120       1130       1140       1150
EKDREHMQTM AFQYHTSVEE IEKWLQSEIE RLKQQGKLNI EQLTAWQRTE 
      1160       1170       1180       1190       1200
QQRILSLLQQ HSNITLEQFQ AKVHNDRRFL MNLAEQHHVH IEEVDNYVKQ 
      1210       1220       1230       1240       1250
VIEDLRKNGQ FEIEQLQTWQ RVERDYIKSL ISEYKNSLST AEYEEKLLAD 
      1260       1270       1280       1290       1300
RAHLKHLADQ YRINVEQIEE WMIAELKRLR GSTEETLKSL SAWQVSELER 
      1310       1320       1330       1340       1350
LQNLVKQQNH LTFVEFEMEL NQERDRLQKL ANQYSVNVVE IEEWLRQQLI 
      1360       1370       1380       1390       1400
NLRTTGQAKV ENLSKWQVEE QQRLIEMLLK KQQEMPYEQV ERELTQDHAR 
      1410       1420       1430       1440       1450
LQSLSQTHHV DIDHVDHWLR EELRRLQSSG LVQIEQQTQW QQKISNGFNN 
      1460       1470       1480       1490       1500
WLEQQRNGAS YQDFVDFLKR DKQRMDGIAT DYHVTVEQVE KWVQKEAARL 
      1510       1520       1530       1540       1550
SLIGVIERPE NNLKYEDISN IWVGDQTDSW KNELVTRLRS VTRQRPFTRQ 
      1560       1570       1580       1590       1600
EFESYLIRNK PIFEQIARQY HVTIEDIHLW LDQSAKNEGL VTTEWQAKER 
      1610       1620       1630       1640       1650
LHIDNLINQQ LRKQQRWTIE ELELRLNNDQ KHLQDAVAQY HVTVEELKVW 
      1660       1670       1680       1690       1700
YKDELNRLLE QRRIDRGSGI SWQNIESQRI YLAIVNNPGI SRQALENRLF 
      1710       1720       1730       1740       1750
RDVHVRASQY QITVEELRQF ILSQLRRFSD MGLIVDNGRQ ANNWHDQERK 
      1760       1770       1780       1790       1800
RLREVVKGVV ITEQELLDFI SQDTSFQTQL AQSYQVGLEQ LAPVQRIFIG 
      1810       1820       1830       1840       1850
NLAREQLLEQ RRLNHLTTWQ QRERDRLYEF IGNQNMTQTE LKTWQIQDSK 
      1860       1870       1880       1890       1900
LLAEFAKRYE ISVQQLSDWQ KKELARINQL ARYYGMSQSD LQQFREGELR 
      1910       1920       1930       1940       1950
QLAYINHRQL LSAAEAQKWE KRHQWTLSRL QSRYGKFGQE LVAWRRTLYL 
      1960       1970       1980       1990       2000
LSQGLIDLPA DSGSNGGYVV DAGSTNATAV YKPIFSKDRG DQPPHTYDES 
      2010       2020       2030       2040       2050
FVEGDEPGLE GETARPRPPN PAPIVSTPKP PLPYSRGGPS GGFEYRRQDY 
      2060       2070       2080       2090       2100
TFNVPVGSAS ASASGGPTGS SASASASLGK WNRASGDEPL QQEVDLGQQQ 
      2110       2120       2130       2140       2150
QIEELGWNEK LEDLGQQTQV EDTDWNQQAE DLGQQQQVQV EDDLHFDQTQ 
      2160       2170       2180 
GHSSSSNSRS QPLQQATKVE VEATSEPSFW EKLKEKLG
Length:2,188
Mass (Da):257,446
Last modified:March 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFFD4715696C33E9E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X2JDD7X2JDD7_DROME
Tiggrin, isoform B
Tig CT36389, Dmel\CG11527, TIG, tig, CG11527
2,188Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ23578 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti7I → V in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti77A → G in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti381E → Q in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti869N → S in AAA56998 (PubMed:7924982).Curated1
Sequence conflicti2157 – 2158Missing in AAA56998 (PubMed:7924982).Curated2
Sequence conflicti2185E → G in AAA56998 (PubMed:7924982).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U09506 mRNA Translation: AAA56998.1
AE014134 Genomic DNA Translation: AAF52380.2
BT010260 mRNA Translation: AAQ23578.1 Frameshift.

NCBI Reference Sequences

More...RefSeqi		NP_001285670.1, NM_001298741.1
NP_477033.1, NM_057685.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0079275; FBpp0078905; FBgn0011722
FBtr0343152; FBpp0309850; FBgn0011722

Database of genes from NCBI RefSeq genomes

More...GeneIDi		33896

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG11527

UCSC genome browser

More...UCSCi		CG11527-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U09506 mRNA Translation: AAA56998.1
AE014134 Genomic DNA Translation: AAF52380.2
BT010260 mRNA Translation: AAQ23578.1 Frameshift.
RefSeqiNP_001285670.1, NM_001298741.1
NP_477033.1, NM_057685.4

3D structure databases

SMRiQ9VMD9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi60053, 4 interactors
IntActiQ9VMD9, 12 interactors
STRINGi7227.FBpp0078905

Proteomic databases

PaxDbiQ9VMD9
PRIDEiQ9VMD9

Genome annotation databases

EnsemblMetazoaiFBtr0079275; FBpp0078905; FBgn0011722
FBtr0343152; FBpp0309850; FBgn0011722
GeneIDi33896
KEGGidme:Dmel_CG11527
UCSCiCG11527-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		33896
FlyBaseiFBgn0011722, Tig

Phylogenomic databases

eggNOGiENOG502S4BN, Eukaryota
HOGENOMiCLU_231371_0_0_1
InParanoidiQ9VMD9
OMAiQNKQWSA
OrthoDBi16764at2759
PhylomeDBiQ9VMD9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		33896, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		33896

Protein Ontology

More...PROi		PR:Q9VMD9

Gene expression databases

BgeeiFBgn0011722, Expressed in arthropod fat body and 33 other tissues
ExpressionAtlasiQ9VMD9, baseline and differential
GenevisibleiQ9VMD9, DM

Family and domain databases

InterProiView protein in InterPro
IPR016084, Haem_Oase-like_multi-hlx
SUPFAMiSSF48613, SSF48613, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTIG_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VMD9
Secondary accession number(s): Q23984, Q6NR23
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 16, 2013
Last sequence update: March 1, 2001
Last modified: April 7, 2021
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again