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Protein
Submitted name:

Adipokinetic hormone receptor, isoform A

Gene

AkhR

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • adipokinetic hormone binding Source: FlyBase
  • adipokinetic hormone receptor activity Source: FlyBase
  • G-protein coupled receptor activity Source: FlyBase
  • neuropeptide receptor activity Source: FlyBase

GO - Biological processi

  • carbohydrate homeostasis Source: FlyBase
  • G-protein coupled receptor signaling pathway Source: FlyBase
  • lipid catabolic process Source: FlyBase
  • lipid homeostasis Source: FlyBase
  • triglyceride homeostasis Source: FlyBase

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Adipokinetic hormone receptor, isoform AImported
Submitted name:
Adipokinetic hormone receptor, isoform BImported
Submitted name:
Adipokinetic hormone receptor, isoform DImported
Submitted name:
GH19447pImported
Gene namesi
Name:AkhRImported
Synonyms:AKH-RImported, AKHRImported, AkhrImported, akhrImported, BEST:GH19447Imported, DAKHRImported, DAKHR-1Imported, DGRHRImported, Dmel\CG11325Imported, GnRHRImported, GRHRImported
ORF Names:CG11325Imported, Dmel_CG11325Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0025595 AkhR

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 64HelicalSequence analysisAdd BLAST23
Transmembranei76 – 101HelicalSequence analysisAdd BLAST26
Transmembranei121 – 142HelicalSequence analysisAdd BLAST22
Transmembranei154 – 176HelicalSequence analysisAdd BLAST23
Transmembranei202 – 228HelicalSequence analysisAdd BLAST27
Transmembranei266 – 288HelicalSequence analysisAdd BLAST23
Transmembranei303 – 322HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9VM96

Expressioni

Gene expression databases

BgeeiFBgn0025595

Interactioni

Protein-protein interaction databases

IntActiQ9VM96, 5 interactors

Structurei

3D structure databases

SMRiQ9VM96
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 319G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST265

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00760000119156
KOiK04280
OMAiKGYFQCV
OrthoDBiEOG091G111M

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VM96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVAEENDH RDLSNWSNVN DTNGTIHLTK DMVFNDGHRL SITVYSILFV
60 70 80 90 100
ISTIGNSTVL YLLTKRRLRG PLRIDIMLMH LAIADLMVTL LLMPMEIVWA
110 120 130 140 150
WTVQWLSTDL MCRLMSFFRV FGLYLSSYVM VCISLDRYFA ILKPLKRSYN
160 170 180 190 200
RGRIMLACAW LGSVVCSIPQ AFLFHLEEHP AVTGYFQCVI FNSFRSDFDE
210 220 230 240 250
KLYQAASMCS MYAFPLIMFI YCYGAIYLEI YRKSQRVLKD VIAERFRRSN
260 270 280 290 300
DDVLSRAKKR TLKMTITIVI VFIICWTPYY TISMWYWLDK HSAGKINPLL
310 320 330 340 350
RKALFIFAST NSCMNPLVYG LYNIRGRMNN NNPSVNNRHT SLSNRLDSSN
360 370 380 390 400
QLMQKQLTNN SLLNGRGQVM AAAVSATTKL ANVVSLKGTA NGNGSAAAAG
410 420 430 440
TVPITPPLTV TIAPLATDDE ANDDSCLSAV TIRCQDQSPI RQK
Length:443
Mass (Da):50,191
Last modified:October 1, 2002 - v2
Checksum:i101111ED035A8AB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF52426.2
AE014134 Genomic DNA Translation: AAN10595.1
BT031198 mRNA Translation: ABY20439.1
AE014134 Genomic DNA Translation: AGB92685.1
RefSeqiNP_001260149.1, NM_001273220.1
NP_477387.1, NM_058039.4
NP_723206.1, NM_164705.3
UniGeneiDm.2227

Genome annotation databases

EnsemblMetazoaiFBtr0079308; FBpp0078938; FBgn0025595
FBtr0079309; FBpp0078939; FBgn0025595
FBtr0332331; FBpp0304609; FBgn0025595
GeneIDi33942
KEGGidme:Dmel_CG11325
UCSCiCG11325-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VM96_DROME
AccessioniPrimary (citable) accession number: Q9VM96
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: July 18, 2018
This is version 140 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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