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Protein
Submitted name:

Lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform A

Gene

LKRSDH

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseImported

Enzyme and pathway databases

ReactomeiR-DME-71064 Lysine catabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform AImported (EC:1.5.1.-Imported)
Submitted name:
Lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform BImported
Gene namesi
Name:LKRSDHImported
Synonyms:anon-WO0149856.1Imported, BEST:CK02318Imported, CK02318Imported, dLKRImported, Dmel\CG7144Imported, LKRImported, SDHImported
ORF Names:CG7144Imported, Dmel_CG7144Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0286198 LKRSDH

Subcellular locationi

Expressioni

Gene expression databases

BgeeiFBgn0025687 Expressed in 22 organ(s), highest expression level in embryonic/larval hemocyte (Drosophila)

Interactioni

Protein-protein interaction databases

IntActiQ9VLX0, 2 interactors
STRINGi7227.FBpp0079118

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 155AlaDh_PNT_NInterPro annotationAdd BLAST131
Domaini195 – 398AlaDh_PNT_CInterPro annotationAdd BLAST204

Phylogenomic databases

eggNOGiKOG0172 Eukaryota
COG1748 LUCA
GeneTreeiENSGT00390000013249
KOiK14157
OMAiIHDKEYV
OrthoDBiEOG091G03D7

Family and domain databases

InterProiView protein in InterPro
IPR007886 AlaDH/PNT_N
IPR007698 AlaDH/PNT_NAD(H)-bd
IPR036291 NAD(P)-bd_dom_sf
IPR032095 Sacchrp_dh_C
IPR005097 Sacchrp_dh_NADP
PfamiView protein in Pfam
PF05222 AlaDh_PNT_N, 1 hit
PF16653 Sacchrp_dh_C, 1 hit
PF03435 Sacchrp_dh_NADP, 1 hit
SMARTiView protein in SMART
SM01002 AlaDh_PNT_C, 1 hit
SM01003 AlaDh_PNT_N, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VLX0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWRVIQLRAT IAHPFTRQRH SRVIAIRRED QSVWERRAPF GPTHVQKLVK
60 70 80 90 100
QNVKVIVQPS NRRAYPMQAY MQAGAHIQED ISDASVIFGV KQVPIDALIP
110 120 130 140 150
GKTYCFFSHT IKAQESNMPL LDAILEKKIR LIDYERIIDE RGARQVAFGK
160 170 180 190 200
YAGVAGMVNI LHGIGLRLLA LGHHTPFMHI GPAHNYRNSS MARQAIRDCG
210 220 230 240 250
YEISLGMMPK SIGPLTFVFT GSGNVSQGAQ EVFSELPIEY VPPEMLRKVA
260 270 280 290 300
EHGNQNKLYG CEVSRSDHLE RREGGGFDAK EYDEFPERYI STFSTKIAPY
310 320 330 340 350
ASVIVNGIYW AVGSPKLISI PDAKNLLRPA NTPWLPTSKG SPALPHRMLA
360 370 380 390 400
ICDISADPGG SIEFMNECTT IDTPFCLYDA DRNKDTKSFK GPGVLVCSID
410 420 430 440 450
NMPTQLPRES TDLFGELLAP HVHDIIKSDA KKPLAEENFS YPIQSAIIAS
460 470 480 490 500
NGQLTEGFQY IQELRESQSH RSRHKMEGSS ESDKKVLVLG AGMVSAPLVE
510 520 530 540 550
WLHREKDVSI TVCSQVKEEA DRLAQQYAGV DSVYLDVNES TGHLQELCGR
560 570 580 590 600
ADVVVSLLPY SLHGMVARYC VAEGTHMVTA SYLNDEISGL HEEAKAKGVT
610 620 630 640 650
IMNEVGLDPG IDHLLALECI HEVQDKGAVV ESFVSYCGGL PAPEHSNNAL
660 670 680 690 700
RYKFSWSPRG VLLNTLSAAK YLSQGQIVEI SGGGELMSSP RSLDFLPGFA
710 720 730 740 750
LEGFPNRDST KYGNLYGLGR DVHTLLRGTI RYKGFSESIK PMQLLGLIDP
760 770 780 790 800
EPHALLHPSG PDVTWRQLVI HLMGMSDSTI FYENLKQKLT ERIGDVDGIE
810 820 830 840 850
SLGLLDDTPV VKLNTPLDTL SHYLSKRLAF ERDERDLVVL RHEVGIRWPD
860 870 880 890 900
GRREERGINF VVYGQPQGHS AMAMTVGKPA AIAAKMILDG EIQERGVLLP
910 920
FTPDIYRPML QRLRSEGLTA TETSRWLN
Length:928
Mass (Da):103,125
Last modified:October 1, 2002 - v2
Checksum:iBD7CC51E88718BB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF52559.2
AE014134 Genomic DNA Translation: AHN54234.1
RefSeqiNP_001285719.1, NM_001298790.1
NP_609150.2, NM_135306.3

Genome annotation databases

EnsemblMetazoaiFBtr0079495; FBpp0079118; FBgn0025687
FBtr0343404; FBpp0310050; FBgn0025687
GeneIDi34064
KEGGidme:Dmel_CG7144
UCSCiCG7144-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VLX0_DROME
AccessioniPrimary (citable) accession number: Q9VLX0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: September 12, 2018
This is version 141 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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