Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 141 (16 Oct 2019)
Sequence version 3 (26 Jun 2013)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Thioester-containing protein 5

Gene

Tep5

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Thioester-containing protein 5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tep5Imported
Synonyms:CG13079Imported, CG13080Imported, Dmel\CG13079Imported, dTEPVImported, TEP5melImported, TepVImported
ORF Names:Dmel_CG13079Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VIT8

PRoteomics IDEntifications database

More...
PRIDEi
Q9VIT8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0264845 Expressed in 3 organ(s), highest expression level in larva

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VIT8 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9VIT8, 2 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini562 – 654A2MInterPro annotationAdd BLAST93
Domaini1088 – 1176A2M_recepInterPro annotationAdd BLAST89

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1366 Eukaryota
ENOG410XRED LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000165966

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VIT8

KEGG Orthology (KO)

More...
KOi
K06530

Identification of Orthologs from Complete Genome Data

More...
OMAi
FTEDFKY

Database of Orthologous Groups

More...
OrthoDBi
354230at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
2.60.40.690, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009048 A-macroglobulin_rcpt-bd
IPR036595 A-macroglobulin_rcpt-bd_sf
IPR011626 Alpha-macroglobulin_TED
IPR013783 Ig-like_fold
IPR001599 Macroglobln_a2
IPR008930 Terpenoid_cyclase/PrenylTrfase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00207 A2M, 1 hit
PF07677 A2M_recep, 2 hits
PF07678 TED_complement, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01360 A2M, 1 hit
SM01361 A2M_recep, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48239 SSF48239, 1 hit
SSF49410 SSF49410, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VIT8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVVVYLNNLP KNDTKCIPIA AYRTHKVDNQ SPSSVVLYDY ATKIKEDTFK
60 70 80 90 100
VPDISSGDCA LTAEGVSGLK FQNSISLYFQ HDTPVVIILI DKDDYIPRDM
110 120 130 140 150
INYRVLVLNE QLRPDTYAED VVICLLDPER NKVDKARKSK VTDKVSIRAI
160 170 180 190 200
SLVQEGNSWT VGVESRRCRW CRIRSSIEYI HLSLPKGDVV KGLDTFHIDL
210 220 230 240 250
TDIAKHKAPI QTTYISTIKA AVEDGDSGEK VTKTTYVYLL ENRYIALNPF
260 270 280 290 300
QLIYSEEMEK GDCYFTKLRK VDERKRFEFD GQLNKSGLYV FQANLSDFPK
310 320 330 340 350
NDKYLAYYDI SVEYKGEEQR IQQTIAQSMG FMIDVTNAYF TPRIDVNFFL
360 370 380 390 400
QIHGRKNDKG FPGALVVGDE FRVTLNSNAP ITHLTAPHFN IYAYYVDDQG
410 420 430 440 450
VLQYTKSQYK VLMSLSALST GYPEEEIKLR IRTETNSYVG ILAIDERISG
460 470 480 490 500
RIKTDDIKHD NLDYQFYTNK LSNALLFNKP PTELPRNHDI DLSYLEEQLE
510 520 530 540 550
DVYLHTYEDI PGSRLGLVTM TNAQIKERIF RYFDMDKYVS ARSISVKYGK
560 570 580 590 600
SPLRYPMKTT ETWLFTDIRK SQKEVTDLEI KLPDTLGTWI VKGFSLHPEK
610 620 630 640 650
GLGIFQSNLT QIRTIKPYSL FIHLPYSVKL GETVRIPVLI VNLFFTCFFF
660 670 680 690 700
KVELALDNEA YGFEDSLEHS QRQLFEIDEY GAKSVFFFKF CPKYTGNFIP
710 720 730 740 750
LDFRATSSVK YTTVYRSLMI IEDKEREIEY SNRALLVNLK DNQEYRSSFH
760 770 780 790 800
MDLPNSRLVE FSLFSDPLVP ILQNLDSSIP DGTGELTMSK MLVNFLVWNY
810 820 830 840 850
LNRTKKLDKA LHTRIKSNFR EGYQKILNYF HEDGSFSYFD PPKANGSIWF
860 870 880 890 900
TSYVLRYLHD IRALIYIDRT ILQKGYRFLL SRQHKDGSFT EDFKYFSRSG
910 920 930 940 950
STLFLTSSVL LALQKQAKPN TIAINKSAPE SDQLVSQLRS VAMQENDQIW
960 970 980 990 1000
WAEDVRNGSP QDVEITLYAL LLMASKVDRP ESAISTVRWF LDQRNIHGEF
1010 1020 1030 1040 1050
ESSQKTVVGL TALIEYAEKW DYNPTAWEVS ISNEDISEKL VAFNLLTQPI
1060 1070 1080 1090 1100
NFHQDTKRLE TTLKSGSLSS KMEAVVCVEF VERSTNASNM AVLEVSLISG
1110 1120 1130 1140 1150
YSSDKSSFKR IRDVEGVGSV DTKNEDSVVI VHFESLAKNE SKCIPVEAYI
1160 1170
THEVTNFKPS SLVIYDNYGR KATEYYQY
Length:1,178
Mass (Da):135,668
Last modified:June 26, 2013 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i42B2FC4CEE335D4D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53828.3

NCBI Reference Sequences

More...
RefSeqi
NP_609988.3, NM_136144.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0331331; FBpp0303749; FBgn0264845

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
35250

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG13079

UCSC genome browser

More...
UCSCi
CG13079-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53828.3
RefSeqiNP_609988.3, NM_136144.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9VIT8, 2 interactors

Proteomic databases

PaxDbiQ9VIT8
PRIDEiQ9VIT8

Genome annotation databases

EnsemblMetazoaiFBtr0331331; FBpp0303749; FBgn0264845
GeneIDi35250
KEGGidme:Dmel_CG13079
UCSCiCG13079-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
35250

Phylogenomic databases

eggNOGiKOG1366 Eukaryota
ENOG410XRED LUCA
GeneTreeiENSGT00940000165966
InParanoidiQ9VIT8
KOiK06530
OMAiFTEDFKY
OrthoDBi354230at2759

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
35250

Gene expression databases

BgeeiFBgn0264845 Expressed in 3 organ(s), highest expression level in larva
GenevisibleiQ9VIT8 DM

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.690, 2 hits
InterProiView protein in InterPro
IPR009048 A-macroglobulin_rcpt-bd
IPR036595 A-macroglobulin_rcpt-bd_sf
IPR011626 Alpha-macroglobulin_TED
IPR013783 Ig-like_fold
IPR001599 Macroglobln_a2
IPR008930 Terpenoid_cyclase/PrenylTrfase
PfamiView protein in Pfam
PF00207 A2M, 1 hit
PF07677 A2M_recep, 2 hits
PF07678 TED_complement, 2 hits
SMARTiView protein in SMART
SM01360 A2M, 1 hit
SM01361 A2M_recep, 1 hit
SUPFAMiSSF48239 SSF48239, 1 hit
SSF49410 SSF49410, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VIT8_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VIT8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: June 26, 2013
Last modified: October 16, 2019
This is version 141 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again