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Protein

tRNA-dihydrouridine(47) synthase [NAD(P)(+)]

Gene

CG10463

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

FMNUniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri74 – 99C3H1-typePROSITE-ProRule annotationAdd BLAST26
Zinc fingeri112 – 137C3H1-typePROSITE-ProRule annotationAdd BLAST26

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processtRNA processingUniRule annotation
LigandFlavoprotein, FMNUniRule annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]UniRule annotation (EC:1.3.1.-UniRule annotation)
Alternative name(s):
tRNA-dihydrouridine synthase 3UniRule annotation
Gene namesi
Name:CG10463Imported
Synonyms:Dmel\CG10463Imported
ORF Names:CG10463Imported, Dmel_CG10463Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0032819 CG10463

PTM / Processingi

Proteomic databases

PaxDbiQ9VIS4
PRIDEiQ9VIS4

Expressioni

Gene expression databases

BgeeiFBgn0032819 Expressed in 24 organ(s), highest expression level in embryo
ExpressionAtlasiQ9VIS4 baseline and differential
GenevisibleiQ9VIS4 DM

Interactioni

Protein-protein interaction databases

IntActiQ9VIS4, 1 interactor
STRINGi7227.FBpp0080828

Structurei

3D structure databases

ProteinModelPortaliQ9VIS4
SMRiQ9VIS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 99C3H1-typeInterPro annotationAdd BLAST26
Domaini112 – 137C3H1-typeInterPro annotationAdd BLAST26

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili177 – 200Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the dus family. Dus3 subfamily.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri74 – 99C3H1-typePROSITE-ProRule annotationAdd BLAST26
Zinc fingeri112 – 137C3H1-typePROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2333 Eukaryota
COG0042 LUCA
GeneTreeiENSGT00550000075134
InParanoidiQ9VIS4
KOiK05544
OMAiWALMKAH
OrthoDBiEOG091G03H2
PhylomeDBiQ9VIS4

Family and domain databases

CDDicd02801 DUS_like_FMN, 1 hit
Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR035587 DUS-like_FMN-bd
IPR001269 tRNA_hU_synthase
IPR018517 tRNA_hU_synthase_CS
IPR000571 Znf_CCCH
PANTHERiPTHR11082 PTHR11082, 1 hit
PfamiView protein in Pfam
PF01207 Dus, 1 hit
PROSITEiView protein in PROSITE
PS01136 UPF0034, 1 hit
PS50103 ZF_C3H1, 2 hits

Sequencei

Sequence statusi: Complete.

Q9VIS4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSGICYIKP EYLVTEADGG SAAANTENSD TNKRKREDGG EVEAGEKKKW
60 70 80 90 100
DKKERKRGQN KNRPVFKDER YSHLCHSLID GTGGEPCSLA NCRYVHDLDA
110 120 130 140 150
YLAAKGEDLG PECYVYTTKG YCARGVSCRF AKAHTDEQGR NLKREDYDEN
160 170 180 190 200
APPTTCNGVS SELQVRLRKH EYDFSRSKEL IKMAEKLRDA RKLKEQQEKE
210 220 230 240 250
KNPSEETGEK QPSETTEILD AEKQTDTKSK PTATGCAIDD SAIGRDADHK
260 270 280 290 300
PAVDFREKLV LSPLTTLGNL PFRRICKEFG ADITCGEMAC AQPLLKGMGQ
310 320 330 340 350
EWALTKRHQS EDVFGVQLCG NNPNMLNQAA QVIHETAQVD FIDLNIGCPI
360 370 380 390 400
DLIYQQGGGS ALMRRTNILE LTVRSCAALS DRLPFTVKMR TGIYADKSVA
410 420 430 440 450
HELLPLVEEW GASAVTLHGR SREQRYTKHA NWAYIEECAA KAKCMPVIGN
460 470 480 490 500
GDILSYEDYM ERRTLAPHVC SVMIGRGALI KPWIFQEIKE KQAWSPSSGQ
510 520 530 540 550
RYEMLQKFCN YGLEHWGSDT KGVETTRRFL LEWQSFLYRY IPEALQTAPP
560 570 580 590 600
QKINARPQKY RGRDEMETLM SSGNAADWVK LSESLLGRVP EGFTFVPKHK

ANAF
Length:604
Mass (Da):68,025
Last modified:May 1, 2000 - v1
Checksum:i465190A1AA954D85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53841.1
RefSeqiNP_610000.1, NM_136156.1
UniGeneiDm.13522

Genome annotation databases

EnsemblMetazoaiFBtr0081290; FBpp0080828; FBgn0032819
GeneIDi35264
KEGGidme:Dmel_CG10463
UCSCiCG10463-RA d. melanogaster

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF53841.1
RefSeqiNP_610000.1, NM_136156.1
UniGeneiDm.13522

3D structure databases

ProteinModelPortaliQ9VIS4
SMRiQ9VIS4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9VIS4, 1 interactor
STRINGi7227.FBpp0080828

Proteomic databases

PaxDbiQ9VIS4
PRIDEiQ9VIS4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0081290; FBpp0080828; FBgn0032819
GeneIDi35264
KEGGidme:Dmel_CG10463
UCSCiCG10463-RA d. melanogaster

Organism-specific databases

FlyBaseiFBgn0032819 CG10463

Phylogenomic databases

eggNOGiKOG2333 Eukaryota
COG0042 LUCA
GeneTreeiENSGT00550000075134
InParanoidiQ9VIS4
KOiK05544
OMAiWALMKAH
OrthoDBiEOG091G03H2
PhylomeDBiQ9VIS4

Miscellaneous databases

GenomeRNAii35264

Gene expression databases

BgeeiFBgn0032819 Expressed in 24 organ(s), highest expression level in embryo
ExpressionAtlasiQ9VIS4 baseline and differential
GenevisibleiQ9VIS4 DM

Family and domain databases

CDDicd02801 DUS_like_FMN, 1 hit
Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR035587 DUS-like_FMN-bd
IPR001269 tRNA_hU_synthase
IPR018517 tRNA_hU_synthase_CS
IPR000571 Znf_CCCH
PANTHERiPTHR11082 PTHR11082, 1 hit
PfamiView protein in Pfam
PF01207 Dus, 1 hit
PROSITEiView protein in PROSITE
PS01136 UPF0034, 1 hit
PS50103 ZF_C3H1, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VIS4_DROME
AccessioniPrimary (citable) accession number: Q9VIS4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 10, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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