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Protein

Cytochrome c oxidase subunit 7A, mitochondrial

Gene

COX7A

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 7A, mitochondrial (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase subunit VIIa
Gene namesi
Name:COX7AImported
ORF Names:CG9603Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0040529 COX7A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 31MitochondrionSequence analysisAdd BLAST31
ChainiPRO_000000615332 – 89Cytochrome c oxidase subunit 7A, mitochondrialAdd BLAST58

Proteomic databases

PaxDbiQ9VHS2
PRIDEiQ9VHS2

Expressioni

Gene expression databases

BgeeiFBgn0040529
ExpressionAtlasiQ9VHS2 baseline and differential
GenevisibleiQ9VHS2 DM

Interactioni

Protein-protein interaction databases

BioGridi72497, 2 interactors
DIPiDIP-17309N
IntActiQ9VHS2, 3 interactors
STRINGi7227.FBpp0296960

Structurei

3D structure databases

ProteinModelPortaliQ9VHS2
SMRiQ9VHS2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c oxidase VIIa family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410JMEB Eukaryota
ENOG410ZTB2 LUCA
InParanoidiQ9VHS2
KOiK02270
OMAiELSVPQK
OrthoDBiEOG091G1BBJ
PhylomeDBiQ9VHS2

Family and domain databases

CDDicd00928 Cyt_c_Oxidase_VIIa, 1 hit
Gene3Di4.10.91.10, 1 hit
InterProiView protein in InterPro
IPR036539 Cyt_c_oxidase_su7a_sf
IPR003177 Cytc_oxidase_su7a_met
PANTHERiPTHR10510 PTHR10510, 1 hit
SUPFAMiSSF81419 SSF81419, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9VHS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNLSRAVVR SFATTAGRRS AAVPKDQIEK GYFEIRKVQE HFQKKDGKPV
60 70 80
FLKGSVVDNV LYRVTVALAL VGIGGMGKLF YELSVPKKE
Length:89
Mass (Da):9,902
Last modified:May 1, 2000 - v1
Checksum:i9220331ED2D07F20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54227.1
BT058048 mRNA Translation: ACM78490.1
RefSeqiNP_652184.2, NM_143927.4
UniGeneiDm.6020

Genome annotation databases

EnsemblMetazoaiFBtr0081855; FBpp0081344; FBgn0040529
GeneIDi50002
KEGGidme:Dmel_CG9603
UCSCiCG9603-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiCOX7A_DROME
AccessioniPrimary (citable) accession number: Q9VHS2
Secondary accession number(s): B9EQX3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: July 18, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

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