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Entry version 158 (07 Apr 2021)
Sequence version 2 (07 Mar 2006)
Previous versions | rss
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Protein

JmjC domain-containing histone demethylation protein 1

Gene

Kdm2

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Fe2+By similarityNote: Binds 1 Fe2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei241SubstrateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi244Iron; catalyticPROSITE-ProRule annotation1
Metal bindingi246Iron; catalyticPROSITE-ProRule annotation1
Binding sitei261SubstrateBy similarity1
Metal bindingi316Iron; catalyticPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri671 – 717CXXC-typePROSITE-ProRule annotationAdd BLAST47

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, Dioxygenase, Oxidoreductase
Biological processTranscription, Transcription regulation
LigandIron, Metal-binding, Zinc

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
1.14.11.27, 1994

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
JmjC domain-containing histone demethylation protein 1 (EC:1.14.11.27By similarity)
Alternative name(s):
Lysine (K)-specific demethylase 2
[Histone-H3]-lysine-36 demethylase 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kdm2
Synonyms:Jhd1
ORF Names:CG11033
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0037659, Kdm2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002267901 – 1345JmjC domain-containing histone demethylation protein 1Add BLAST1345

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei53Phosphotyrosine1 Publication1
Modified residuei58Phosphoserine1 Publication1
Modified residuei79Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VHH9

PRoteomics IDEntifications database

More...
PRIDEi
Q9VHH9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9VHH9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0037659, Expressed in eye disc (Drosophila) and 38 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VHH9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VHH9, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
66257, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VHH9, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0289915

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VHH9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini180 – 348JmjCPROSITE-ProRule annotationAdd BLAST169
Domaini1059 – 1105F-boxAdd BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi592 – 669Gly-richAdd BLAST78

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The JmjC domain mediates the demethylation activity.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the JHDM1 histone demethylase family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri671 – 717CXXC-typePROSITE-ProRule annotationAdd BLAST47

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1633, Eukaryota
KOG1947, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000167551

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003540_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VHH9

Identification of Orthologs from Complete Genome Data

More...
OMAi
NYDYKPR

Database of Orthologous Groups

More...
OrthoDBi
324938at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VHH9

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041667, Cupin_8
IPR001810, F-box_dom
IPR003347, JmjC_dom
IPR001611, Leu-rich_rpt
IPR006553, Leu-rich_rpt_Cys-con_subtyp
IPR032675, LRR_dom_sf
IPR002857, Znf_CXXC
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13621, Cupin_8, 1 hit
PF12937, F-box-like, 1 hit
PF13516, LRR_6, 1 hit
PF16866, PHD_4, 1 hit
PF02008, zf-CXXC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00256, FBOX, 1 hit
SM00558, JmjC, 1 hit
SM00367, LRR_CC, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51184, JMJC, 1 hit
PS51058, ZF_CXXC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VHH9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTAVETGSS PAKSNSNNSS SGGNNNNGNG NLSPNAKGVQ RRQLRERKQR
60 70 80 90 100
KLYLEEWSLG DEDGEGTRGF SVAEKLESSK FAQAGMVREM RGCDLTVAFL
110 120 130 140 150
QQHGFNIPLL FRDKAGLGLR MPDPQEFTVN DVRLCVGSRR LLDVMDVNTQ
160 170 180 190 200
KNLQMTMKEW QQYYDSPQKD RLLNVISLEF SHTRLDRFVQ SPEIVRQIDW
210 220 230 240 250
VDVVWPKQLK DAQREGTNLL GGMMYPKVQK YCLMSVKNCY TDFHIDFGGT
260 270 280 290 300
SVWYHILRGS KVFWLIPPTD RNLQLYEKWV LSGKQADIFF GDTVEKCARV
310 320 330 340 350
YLTAGNTFFI PTGWIHAVYT PTQSLVFGGN FLHSFGIVKQ LKTASVEDST
360 370 380 390 400
KVPQKFRYPF FTEMLWYVLA RYVHTLLGHS HLEGEASLSE DEMAARPHTH
410 420 430 440 450
LTHHELFGLK EIVMYLYDLP PQKKNVPSLV LDPVALIKDV RSLVERHCKD
460 470 480 490 500
QQDLAITGVS VLKSPPGSQP PFLLYDRTRV KQEIKQEIAR KNAEVIREQQ
510 520 530 540 550
QLEAGRAREA ESDTSQSTGV GSVIGMGAGV EYSNGVMKKE QLENGSGVTV
560 570 580 590 600
GGHGSQPEAT FALPTDTLKY RPPKKMHLAT ALVAAAASSS SGGGGPVAGV
610 620 630 640 650
GGSAVVGSSH SPTGGGVGPV TGAGGAISVI ATSSSYIEGG QVGGILNMDN
660 670 680 690 700
CHSPEGGGAK LSPNLTGTGQ PRRRRTRCKN CAACQRSDCG TCPFCMDMVK
710 720 730 740 750
FGGPGRAKQT CMMRQCLSPM LPVTAQCVYC HLDGWRQTPV SPQTKQLASA
760 770 780 790 800
DGPSALMECS VCYEIAHPDC ALSQLDGTED AADAKGIVNE DLPNSWECPS
810 820 830 840 850
CCRSGKNYDY KPRHFRARQK SSEVRRVSVS HGQGGAEGHA DGNTLLPPPV
860 870 880 890 900
GQYNDFVFTS ESEMESGTVS GHMTHWKHGM KRHHQLEVKT ERNNSCDTPS
910 920 930 940 950
PGISPNAIGG DSKVGKRRKS DDGTSVSSSM HESNDAPCGS SAEGAGGAGN
960 970 980 990 1000
ANVSTNQWSG SGGGGGSRKK NSIRSQLAQQ MLNSSTRVLK KPQYVVRPAS
1010 1020 1030 1040 1050
GTGSSSSSGN GGSASATNGI SNGSNQSGAN SCGAGNGERG TNNGGLSGSN
1060 1070 1080 1090 1100
GLGNQHYSSS QNLALDPTVL KIIFRYLPQD TLVTCCSVCK VWSNAAVDPD
1110 1120 1130 1140 1150
LWKKMNCSEH KMSASLLTAI VRRQPEHLIL DWTQIAKRQL AWLVARLPAL
1160 1170 1180 1190 1200
KNLSLQNCPI QAVLALHTCL CPPLQTLDLS FVRGLNDAAI RDILSPPKDS
1210 1220 1230 1240 1250
RPGLSDSKTR LRDLKVMKLA GTDISDVAVR YITQSLPYLR HLDLSSCQRI
1260 1270 1280 1290 1300
TDAGVAQIGT STTATARLTE LNLSACRLVS ENALEHLAKC EGLIWLDLRH
1310 1320 1330 1340
VPQVSTQSVI RFASNSKHDL CVRDIKLVER RRRNSTTANR SWHHD
Length:1,345
Mass (Da):146,178
Last modified:March 7, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3157AD3B9E1AE619
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4KFJ7A0A0B4KFJ7_DROME
[Histone H3]-dimethyl-L-lysine(36) ...
Kdm2 dKDM2, dKdm2, dkdm2, Dmel\CG11033, dRAF1
1,345Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti469Q → L in AAQ22410 (Ref. 3) Curated1
Sequence conflicti950N → T in AAQ22410 (Ref. 3) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54335.2
BT009941 mRNA Translation: AAQ22410.1

NCBI Reference Sequences

More...
RefSeqi
NP_001262400.1, NM_001275471.1
NP_001262401.1, NM_001275472.1
NP_001262402.1, NM_001275473.1
NP_649864.2, NM_141607.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0300691; FBpp0289915; FBgn0037659
FBtr0336758; FBpp0307734; FBgn0037659
FBtr0336759; FBpp0307735; FBgn0037659
FBtr0336760; FBpp0307736; FBgn0037659

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
41090

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG11033

UCSC genome browser

More...
UCSCi
CG11033-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54335.2
BT009941 mRNA Translation: AAQ22410.1
RefSeqiNP_001262400.1, NM_001275471.1
NP_001262401.1, NM_001275472.1
NP_001262402.1, NM_001275473.1
NP_649864.2, NM_141607.3

3D structure databases

SMRiQ9VHH9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi66257, 11 interactors
IntActiQ9VHH9, 1 interactor
STRINGi7227.FBpp0289915

PTM databases

iPTMnetiQ9VHH9

Proteomic databases

PaxDbiQ9VHH9
PRIDEiQ9VHH9

Genome annotation databases

EnsemblMetazoaiFBtr0300691; FBpp0289915; FBgn0037659
FBtr0336758; FBpp0307734; FBgn0037659
FBtr0336759; FBpp0307735; FBgn0037659
FBtr0336760; FBpp0307736; FBgn0037659
GeneIDi41090
KEGGidme:Dmel_CG11033
UCSCiCG11033-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
41090
FlyBaseiFBgn0037659, Kdm2

Phylogenomic databases

eggNOGiKOG1633, Eukaryota
KOG1947, Eukaryota
GeneTreeiENSGT00940000167551
HOGENOMiCLU_003540_0_0_1
InParanoidiQ9VHH9
OMAiNYDYKPR
OrthoDBi324938at2759
PhylomeDBiQ9VHH9

Enzyme and pathway databases

BRENDAi1.14.11.27, 1994

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
41090, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
41090

Protein Ontology

More...
PROi
PR:Q9VHH9

Gene expression databases

BgeeiFBgn0037659, Expressed in eye disc (Drosophila) and 38 other tissues
ExpressionAtlasiQ9VHH9, baseline and differential
GenevisibleiQ9VHH9, DM

Family and domain databases

Gene3Di3.30.40.10, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR041667, Cupin_8
IPR001810, F-box_dom
IPR003347, JmjC_dom
IPR001611, Leu-rich_rpt
IPR006553, Leu-rich_rpt_Cys-con_subtyp
IPR032675, LRR_dom_sf
IPR002857, Znf_CXXC
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF13621, Cupin_8, 1 hit
PF12937, F-box-like, 1 hit
PF13516, LRR_6, 1 hit
PF16866, PHD_4, 1 hit
PF02008, zf-CXXC, 1 hit
SMARTiView protein in SMART
SM00256, FBOX, 1 hit
SM00558, JmjC, 1 hit
SM00367, LRR_CC, 5 hits
PROSITEiView protein in PROSITE
PS51184, JMJC, 1 hit
PS51058, ZF_CXXC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJHD1_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VHH9
Secondary accession number(s): Q7YU79
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: March 7, 2006
Last modified: April 7, 2021
This is version 158 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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