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Protein
Submitted name:

IP11374p

Gene

Task7

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • potassium channel activity Source: FlyBase
  • potassium ion leak channel activity Source: GO_Central
  • protein heterodimerization activity Source: FlyBase

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelUniRule annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Enzyme and pathway databases

ReactomeiR-DME-1299316 TWIK-releated acid-sensitive K+ channel (TASK)
R-DME-5576886 Phase 4 - resting membrane potential

Names & Taxonomyi

Protein namesi
Submitted name:
IP11374pImported
Submitted name:
TWIK-related acid-sensitive K[+] channel 7Imported
Gene namesi
Name:Task7Imported
Synonyms:Dmel\CG9361Imported, dTASK-7Imported, K2P-TASK7Imported
ORF Names:CG9361Imported, Dmel_CG9361Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0037690 Task7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei79 – 97HelicalSequence analysisAdd BLAST19
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21
Transmembranei160 – 179HelicalSequence analysisAdd BLAST20
Transmembranei191 – 209HelicalSequence analysisAdd BLAST19
Transmembranei221 – 247HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0037690 Expressed in 8 organ(s), highest expression level in head

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7227.FBpp0081523

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 133Ion_trans_2InterPro annotationAdd BLAST57
Domaini170 – 248Ion_trans_2InterPro annotationAdd BLAST79

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4404 Eukaryota
ENOG410XRZJ LUCA
GeneTreeiENSGT00760000118858
KOiK04919
OMAiCSGTQRS
OrthoDBiEOG091G08DH

Family and domain databases

InterProiView protein in InterPro
IPR003280 2pore_dom_K_chnl
IPR003092 2pore_dom_K_chnl_TASK
IPR013099 K_chnl_dom
PfamiView protein in Pfam
PF07885 Ion_trans_2, 2 hits
PIRSFiPIRSF038061 K_channel_subfamily_K_type, 1 hit
PRINTSiPR01333 2POREKCHANEL
PR01095 TASKCHANNEL

Sequencei

Sequence statusi: Complete.

Q9VHE0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMKRQNVRTL SLVVCTFTYL LIGAAVFDSL ESPTEAKRWE FLQTVKNNFV
60 70 80 90 100
RKYNVTDEDF RVMEIVIIEN KPHKAGPQWK FAGAFYFSTV VLAMIGYGHS
110 120 130 140 150
TPVTIPGKAF CMGYAMVGIP LGLVMFQSIG ERLNKFASVI IRRAKRASGA
160 170 180 190 200
RCTDATEMNL MLATGMLSSI IITTGAAVFS RYEGWSYFDS FYYCFVTLTT
210 220 230 240 250
IGFGDYVALQ NDQALTNKPG YVALSLVFIL FGLAVVAASI NLLVLRFMTM
260 270 280 290 300
QAEDAKRDEQ DAQNLAGNAQ PVTFDDESTY NMHGKLLENN YTTENDETAS
310 320 330 340
LCSCTCMGGT RCLNHEQFVD PDFQPTDIIE STLCLKRASV
Length:340
Mass (Da):37,841
Last modified:May 1, 2000 - v1
Checksum:i018D756D21F8D57A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54374.1
BT024313 mRNA Translation: ABC86375.1
RefSeqiNP_649891.1, NM_141634.2
UniGeneiDm.27247

Genome annotation databases

EnsemblMetazoaiFBtr0082045; FBpp0081523; FBgn0037690
GeneIDi41125
KEGGidme:Dmel_CG9361
UCSCiCG9361-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VHE0_DROME
AccessioniPrimary (citable) accession number: Q9VHE0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 12, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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