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Entry version 156 (02 Jun 2021)
Sequence version 2 (01 Oct 2002)
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Protein
Submitted name:

Sarcomere length short, isoform B

Gene

sals

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: FlyBase

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Sarcomere length short, isoform BImported
Submitted name:
Sarcomere length short, isoform CImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:salsImported
Synonyms:CG14703Imported, CG6771Imported, Dmel\CG31374Imported
ORF Names:CG31374Imported, Dmel_CG31374Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0051374, sals

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0051374, Expressed in pupa and 25 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0081875

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini399 – 416WH2InterPro annotationAdd BLAST18
Domaini447 – 464WH2InterPro annotationAdd BLAST18

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 403DisorderedSequence analysisAdd BLAST403
Regioni706 – 759DisorderedSequence analysisAdd BLAST54
Regioni773 – 887DisorderedSequence analysisAdd BLAST115

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili564 – 591Sequence analysisAdd BLAST28
Coiled coili617 – 672Sequence analysisAdd BLAST56
Coiled coili898 – 925Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi32 – 64Polar residuesSequence analysisAdd BLAST33
Compositional biasi101 – 116Polar residuesSequence analysisAdd BLAST16
Compositional biasi159 – 200Acidic residuesSequence analysisAdd BLAST42
Compositional biasi222 – 259Basic and acidic residuesSequence analysisAdd BLAST38
Compositional biasi285 – 344Basic and acidic residuesSequence analysisAdd BLAST60
Compositional biasi348 – 374Pro residuesSequence analysisAdd BLAST27
Compositional biasi381 – 403Basic and acidic residuesSequence analysisAdd BLAST23
Compositional biasi740 – 759Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi773 – 820Basic and acidic residuesSequence analysisAdd BLAST48
Compositional biasi821 – 866Acidic residuesSequence analysisAdd BLAST46
Compositional biasi870 – 887Basic and acidic residuesSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QVYP, Eukaryota

Database of Orthologous Groups

More...
OrthoDBi
635351at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003124, WH2_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02205, WH2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00246, WH2, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51082, WH2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q9VGN4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPFVTPRAGT SSASSAPGGR TTFRPPWVKD DGGTSGTSST TKPTATPWAK
60 70 80 90 100
KTATTTTASP ATKENGEKPT VAKPKATATT TAAARKTSTP EPAKKTIEPV
110 120 130 140 150
KKSSLATSTT AAKKTPEPVN TKKAPEPIKK VAPTVGPKKP VATTSALKKK
160 170 180 190 200
KEPTPPPESS SEEEESEEEE ETEEETESEE EESEEESESE EEESEEEDTT
210 220 230 240 250
VDEKVPEHVK KAAQLRPTTV NKKPEPESEL TQRFTMEKPK LRSVVVKRDK
260 270 280 290 300
SLKKMATEDD DEAEEGETEE ERDRRRRFKL EKPKLRHVKR EEKPLPSKST
310 320 330 340 350
DDLAKIRPVL KKVPKIDELL KEPKEEPKPE FTTKTLRKAS IKREPSIKSV
360 370 380 390 400
PAPPPLPSLV PKAPPPPPPP LAPGEKRVLS STQKETLEKL RTRPRRRPDW
410 420 430 440 450
SEMMKEVESG KKLRHVACND RSQPILTCKS ITKLDDKFIY ETEKGNSHNK
460 470 480 490 500
LLKQIQGGIK LKPTKTNDRS KPVLDGLRKF RRQMTIEEQL QKSQSKINML
510 520 530 540 550
SEAPSSHALG PGSATALGAG GSRPSIVSAM SIDEESPDEL DDIDKIRDDL
560 570 580 590 600
QSTKQMLALE LRNREAQDRE NKKLLAKIRT LETELEREKS REKNLEYGSN
610 620 630 640 650
VIVATMDPTP TAEQTYVNSL KREVEDARKV SKEVEQNYQS TAEQLVEAKT
660 670 680 690 700
EIEEQRRQIQ LLERKLAAAL QATPSTNRPH ISNCFAYDDD DYDDCFHYDH
710 720 730 740 750
YHAARHQGGG SLDGSRRPSD ANFGRDSSPE LEPEVSESDP DEPEEKKVER
760 770 780 790 800
RERRSGKELK ILRSKLTKLK VKEEAAKKEK DALKQAMKKN QSILKEENKK
810 820 830 840 850
FKKLEKEVQK MAASMKLDED DVDGEEKDED EEEAEEEHAS EEEEESDDES
860 870 880 890 900
EESESEESEA ETGSESEPED SPNSAKKANV EPRVKKHESR FAAMKKCNVL
910 920 930
LQANVDNLQD QIVQVRSRAT NLQDELDAVI ADLGF
Length:935
Mass (Da):104,907
Last modified:October 1, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFDF542DBCB857C43
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9VGN5Q9VGN5_DROME
Sarcomere length short, isoform A
sals CG14703, CG6771, Dmel\CG31374, CG31374, Dmel_CG31374
533Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q58CJ5Q58CJ5_DROME
GH01093p
sals CG14703, CG6771, Dmel\CG31374, CG31374, Dmel_CG31374
899Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4K633A0A0B4K633_DROME
Sarcomere length short, isoform E
sals CG14703, CG6771, Dmel\CG31374, CG31374, Dmel_CG31374
563Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4LI42A0A0B4LI42_DROME
Sarcomere length short, isoform H
sals CG14703, CG6771, Dmel\CG31374, CG31374, Dmel_CG31374
599Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54642.2
AE014297 Genomic DNA Translation: AAO41543.1

NCBI Reference Sequences

More...
RefSeqi
NP_731573.1, NM_169390.2
NP_788637.1, NM_176460.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0082399; FBpp0081875; FBgn0051374
FBtr0082401; FBpp0081877; FBgn0051374

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
41377

UCSC genome browser

More...
UCSCi
CG31374-RB, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54642.2
AE014297 Genomic DNA Translation: AAO41543.1
RefSeqiNP_731573.1, NM_169390.2
NP_788637.1, NM_176460.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7227.FBpp0081875

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
41377

Genome annotation databases

EnsemblMetazoaiFBtr0082399; FBpp0081875; FBgn0051374
FBtr0082401; FBpp0081877; FBgn0051374
GeneIDi41377
UCSCiCG31374-RB, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
41377
FlyBaseiFBgn0051374, sals

Phylogenomic databases

eggNOGiENOG502QVYP, Eukaryota
OrthoDBi635351at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
41377, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
41377

Gene expression databases

BgeeiFBgn0051374, Expressed in pupa and 25 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR003124, WH2_dom
PfamiView protein in Pfam
PF02205, WH2, 1 hit
SMARTiView protein in SMART
SM00246, WH2, 2 hits
PROSITEiView protein in PROSITE
PS51082, WH2, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VGN4_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VGN4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: June 2, 2021
This is version 156 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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