UniProtKB - Q9VGC3 (COG1_DROME)
Protein
Conserved oligomeric Golgi complex subunit 1
Gene
Cog1
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Required for normal Golgi function.By similarity
GO - Biological processi
- Golgi organization Source: FlyBase
- intra-Golgi vesicle-mediated transport Source: FlyBase
- protein transport Source: UniProtKB-KW
Keywordsi
Biological process | Protein transport, Transport |
Enzyme and pathway databases
Reactomei | R-DME-6807878, COPI-mediated anterograde transport R-DME-6811438, Intra-Golgi traffic |
Names & Taxonomyi
Protein namesi | Recommended name: Conserved oligomeric Golgi complex subunit 1Short name: COG complex subunit 1 Alternative name(s): Component of oligomeric Golgi complex 1Imported |
Gene namesi | Name:Cog1Imported ORF Names:CG4848Imported |
Organismi | Drosophila melanogaster (Fruit fly) |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0037998, Cog1 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
Golgi apparatus
- Golgi apparatus Source: FlyBase
- Golgi membrane Source: UniProtKB-SubCell
- Golgi transport complex Source: FlyBase
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000213493 | 1 – 886 | Conserved oligomeric Golgi complex subunit 1Add BLAST | 886 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 839 | Phosphoserine1 Publication | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | Q9VGC3 |
PRIDEi | Q9VGC3 |
PTM databases
iPTMneti | Q9VGC3 |
Expressioni
Gene expression databases
Bgeei | FBgn0037998, Expressed in saliva-secreting gland and 42 other tissues |
ExpressionAtlasi | Q9VGC3, baseline and differential |
Genevisiblei | Q9VGC3, DM |
Interactioni
Subunit structurei
Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
By similarityProtein-protein interaction databases
BioGRIDi | 66592, 3 interactors |
DIPi | DIP-23267N |
IntActi | Q9VGC3, 3 interactors |
STRINGi | 7227.FBpp0082093 |
Family & Domainsi
Sequence similaritiesi
Belongs to the COG1 family.Curated
Phylogenomic databases
eggNOGi | KOG2033, Eukaryota |
GeneTreei | ENSGT00390000017136 |
HOGENOMi | CLU_012605_0_0_1 |
InParanoidi | Q9VGC3 |
OrthoDBi | 221637at2759 |
PhylomeDBi | Q9VGC3 |
Family and domain databases
InterProi | View protein in InterPro IPR033370, COG1 |
PANTHERi | PTHR31658, PTHR31658, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q9VGC3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTANLLNLNV DTLFEQHSVS EIDEVHKKIQ SVVENKREEL RTHVGERYRD
60 70 80 90 100
LLQAADTIAA MQTSAGTLME QVRHVQANCR SLNEQQLLGF QSTANASAKD
110 120 130 140 150
AALKERNAGK KLQTYYGTMA QIKLLTALPE LIWTHLDNDR FYAATELFIF
160 170 180 190 200
SRHISTGLQL DGQSALMQKL PVARKQWEIL RPFHVTIKQA ILTALEREEL
210 220 230 240 250
LQEMTVDCLQ SLLLLDKSDL STVLKSFLNL RSSAFLNCLQ SGPSEPRRVK
260 270 280 290 300
DRILASLNVL NSTVELLDKC LLGYSLLFSR LEECASSTCP PSINRMESSE
310 320 330 340 350
RQLVHLLPEI IAGFKPQFDV PQLTPEQLGS SLQQWLDKMN ALAAAHLQQV
360 370 380 390 400
FALVTNMQTI QDIKSAARTN GRPDFVRLEQ QLHLKRSQLD FYARKYVPLI
410 420 430 440 450
NARVREIIRS SWASAMKLTY EQVLLLIEAG QSQPPLQIWR EQSDDLPLSL
460 470 480 490 500
AAALSDQPKR LANRTKGYDG ATIELCKRFD SHLADIVQEL NVMLQEQTTR
510 520 530 540 550
AEDKVSLIEF LRETAEEQLT EYLSNLKGLE LRERPALLLA LRNSLALVEL
560 570 580 590 600
CPNLKLCFCQ PSSWRQWTDN SAGLGIEHWQ RICGLIEKEM LSFWLVIVDD
610 620 630 640 650
VLAGHNCEEK LPKVINHEVV LSDFALWQTL TLEQRDEDQE QSVQSTIRIP
660 670 680 690 700
SQPRLSLQTY LHQLIQALNS VVPQTLPPKV LQAFIQRLIG KLLCHYEGLA
710 720 730 740 750
HAECTKASQN IALQLYFDLK FLERVFAISR EERTLYDQIH AQQNQLRDYI
760 770 780 790 800
DPFDFELFAE HITAHVSRAA SRLQGELGVL TPSAAAPSQG AAAASSLAHE
810 820 830 840 850
ADPNVLCLSS SGSTSLWFPL LPIVMPQAAG RVTSAERKSP IQEPVEKTAT
860 870 880
TTPTRKSGGN GARKGDSSKS KSSAASFFGM SQEWFR
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A0B4KGW7 | A0A0B4KGW7_DROME | Conserved oligomeric Golgi complex ... | Cog1 cog1, Dmel\CG4848, CG4848, Dmel_CG4848 | 886 | Annotation score: | ||
A0A0B4KH76 | A0A0B4KH76_DROME | Conserved oligomeric Golgi complex ... | Cog1 cog1, Dmel\CG4848, CG4848, Dmel_CG4848 | 854 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF54760.1 AY058448 mRNA Translation: AAL13677.1 |
RefSeqi | NP_001262497.1, NM_001275568.1 NP_650162.1, NM_141905.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0082624; FBpp0082093; FBgn0037998 FBtr0334597; FBpp0306664; FBgn0037998 |
GeneIDi | 41479 |
KEGGi | dme:Dmel_CG4848 |
UCSCi | CG4848-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF54760.1 AY058448 mRNA Translation: AAL13677.1 |
RefSeqi | NP_001262497.1, NM_001275568.1 NP_650162.1, NM_141905.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 66592, 3 interactors |
DIPi | DIP-23267N |
IntActi | Q9VGC3, 3 interactors |
STRINGi | 7227.FBpp0082093 |
PTM databases
iPTMneti | Q9VGC3 |
Proteomic databases
PaxDbi | Q9VGC3 |
PRIDEi | Q9VGC3 |
Genome annotation databases
EnsemblMetazoai | FBtr0082624; FBpp0082093; FBgn0037998 FBtr0334597; FBpp0306664; FBgn0037998 |
GeneIDi | 41479 |
KEGGi | dme:Dmel_CG4848 |
UCSCi | CG4848-RA, d. melanogaster |
Organism-specific databases
CTDi | 9382 |
FlyBasei | FBgn0037998, Cog1 |
Phylogenomic databases
eggNOGi | KOG2033, Eukaryota |
GeneTreei | ENSGT00390000017136 |
HOGENOMi | CLU_012605_0_0_1 |
InParanoidi | Q9VGC3 |
OrthoDBi | 221637at2759 |
PhylomeDBi | Q9VGC3 |
Enzyme and pathway databases
Reactomei | R-DME-6807878, COPI-mediated anterograde transport R-DME-6811438, Intra-Golgi traffic |
Miscellaneous databases
BioGRID-ORCSi | 41479, 1 hit in 1 CRISPR screen |
GenomeRNAii | 41479 |
PROi | PR:Q9VGC3 |
Gene expression databases
Bgeei | FBgn0037998, Expressed in saliva-secreting gland and 42 other tissues |
ExpressionAtlasi | Q9VGC3, baseline and differential |
Genevisiblei | Q9VGC3, DM |
Family and domain databases
InterProi | View protein in InterPro IPR033370, COG1 |
PANTHERi | PTHR31658, PTHR31658, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | COG1_DROME | |
Accessioni | Q9VGC3Primary (citable) accession number: Q9VGC3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 15, 2002 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 10, 2021 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Drosophila
Drosophila: entries, gene names and cross-references to FlyBase - SIMILARITY comments
Index of protein domains and families