UniProtKB - Q9VG73 (ILF2_DROME)
Protein
Interleukin enhancer-binding factor 2 homolog
Gene
CG5641
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
May regulate transcription of undefined genes.By similarity
GO - Molecular functioni
- DNA binding Source: UniProtKB
- double-stranded RNA binding Source: UniProtKB
GO - Biological processi
- mRNA splicing, via spliceosome Source: FlyBase
- positive regulation of transcription, DNA-templated Source: UniProtKB
Keywordsi
Molecular function | Activator, DNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
Reactomei | R-DME-6798695, Neutrophil degranulation |
Names & Taxonomyi
Protein namesi | Recommended name: Interleukin enhancer-binding factor 2 homolog |
Gene namesi | ORF Names:CG5641 |
Organismi | Drosophila melanogaster (Fruit fly) |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0038046, CG5641 |
Subcellular locationi
Nucleus
- Nucleus By similarity
Nucleus
- catalytic step 2 spliceosome Source: FlyBase
- nucleolus Source: UniProtKB
- nucleus Source: UniProtKB
- precatalytic spliceosome Source: FlyBase
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000126069 | 1 – 396 | Interleukin enhancer-binding factor 2 homologAdd BLAST | 396 |
Proteomic databases
PaxDbi | Q9VG73 |
PRIDEi | Q9VG73 |
Expressioni
Gene expression databases
Bgeei | FBgn0038046, Expressed in multi-cellular organism and 56 other tissues |
Genevisiblei | Q9VG73, DM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 66627, 6 interactors |
IntActi | Q9VG73, 5 interactors |
STRINGi | 7227.FBpp0082066 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 22 – 379 | DZFPROSITE-ProRule annotationAdd BLAST | 358 |
Phylogenomic databases
eggNOGi | KOG3793, Eukaryota |
GeneTreei | ENSGT00940000154879 |
HOGENOMi | CLU_064863_1_0_1 |
InParanoidi | Q9VG73 |
OMAi | AVEMSVW |
OrthoDBi | 1145212at2759 |
PhylomeDBi | Q9VG73 |
Family and domain databases
Gene3Di | 3.30.460.10, 1 hit |
InterProi | View protein in InterPro IPR006561, DZF_dom IPR043519, NT_sf |
Pfami | View protein in Pfam PF07528, DZF, 1 hit |
SMARTi | View protein in SMART SM00572, DZF, 1 hit |
SUPFAMi | SSF81301, SSF81301, 1 hit |
PROSITEi | View protein in PROSITE PS51703, DZF, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VG73-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVRGALRGGR PMRGGIRPPF KKTFVPRHPF DLTLAEVFFP KVPSAGAVDD
60 70 80 90 100
SALTAALLKR NQDLSPTPSE QTAIGNLVTK VQAVLDNLVV APGDLTTCQL
110 120 130 140 150
EEVRQVGSFK KGTILTGNNV ADVVVILKTL PTKEAVDALA KKVEADLKAS
160 170 180 190 200
MKTEVLTKGD QHTVQIHERG FDIANVHAKV RILIATLPQN LRKLEPEIHL
210 220 230 240 250
DHKLMQSHLA AIRHTRWFEE NAHHSSIKVL IRILKDLTRR FDAFSPLSAW
260 270 280 290 300
MLDLIAHLAI MNNPSRQALP INLAFRRVFQ LLSAGLFLPG SAGITDPTEP
310 320 330 340 350
GHIRVHTAMT LEQQDVCCYT SQTLLRVLAH GGYKHILGLE GNTSVVREMS
360 370 380 390
VWNGVCISPL TAVYEKPTDK KEGDLEEDID MIENENEEEG SDDGAE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF54812.1 AY051610 mRNA Translation: AAK93034.1 |
RefSeqi | NP_650196.1, NM_141939.4 |
Genome annotation databases
EnsemblMetazoai | FBtr0082594; FBpp0082066; FBgn0038046 |
GeneIDi | 41529 |
KEGGi | dme:Dmel_CG5641 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF54812.1 AY051610 mRNA Translation: AAK93034.1 |
RefSeqi | NP_650196.1, NM_141939.4 |
3D structure databases
SMRi | Q9VG73 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 66627, 6 interactors |
IntActi | Q9VG73, 5 interactors |
STRINGi | 7227.FBpp0082066 |
Proteomic databases
PaxDbi | Q9VG73 |
PRIDEi | Q9VG73 |
Genome annotation databases
EnsemblMetazoai | FBtr0082594; FBpp0082066; FBgn0038046 |
GeneIDi | 41529 |
KEGGi | dme:Dmel_CG5641 |
Organism-specific databases
FlyBasei | FBgn0038046, CG5641 |
Phylogenomic databases
eggNOGi | KOG3793, Eukaryota |
GeneTreei | ENSGT00940000154879 |
HOGENOMi | CLU_064863_1_0_1 |
InParanoidi | Q9VG73 |
OMAi | AVEMSVW |
OrthoDBi | 1145212at2759 |
PhylomeDBi | Q9VG73 |
Enzyme and pathway databases
Reactomei | R-DME-6798695, Neutrophil degranulation |
Miscellaneous databases
BioGRID-ORCSi | 41529, 0 hits in 1 CRISPR screen |
GenomeRNAii | 41529 |
PROi | PR:Q9VG73 |
Gene expression databases
Bgeei | FBgn0038046, Expressed in multi-cellular organism and 56 other tissues |
Genevisiblei | Q9VG73, DM |
Family and domain databases
Gene3Di | 3.30.460.10, 1 hit |
InterProi | View protein in InterPro IPR006561, DZF_dom IPR043519, NT_sf |
Pfami | View protein in Pfam PF07528, DZF, 1 hit |
SMARTi | View protein in SMART SM00572, DZF, 1 hit |
SUPFAMi | SSF81301, SSF81301, 1 hit |
PROSITEi | View protein in PROSITE PS51703, DZF, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ILF2_DROME | |
Accessioni | Q9VG73Primary (citable) accession number: Q9VG73 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 12, 2005 |
Last sequence update: | May 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 128 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Drosophila
Drosophila: entries, gene names and cross-references to FlyBase