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UniProtKB - Q9VFT4 (Q9VFT4_DROME)

Entry version 176 (19 Jan 2022)
Sequence version 1 (01 May 2000)
Previous versions | rss
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Protein
Submitted name:

AT27578p

Gene

rin

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AT27578pImported
Submitted name:
LD31194pImported
Submitted name:
Rasputin, isoform BImported
Submitted name:
Rasputin, isoform EImported
Submitted name:
Rasputin, isoform FImported
Submitted name:
Rasputin, isoform GImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rinImported
Synonyms:cg9412Imported, Dmel\CG9412Imported, NtsImported, raspImported, RINImported, RinImported
ORF Names:CG9412Imported, Dmel_CG9412Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0015778, rin

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		VectorBase:FBgn0015778

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0015778, Expressed in imaginal disc and 39 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q9VFT4, 2 interactors

STRING: functional protein association networks

More...STRINGi		7227.FBpp0082264

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini16 – 129NTF2InterPro annotationAdd BLAST114
Domaini493 – 581RRMInterPro annotationAdd BLAST89

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni302 – 357DisorderedSequence analysisAdd BLAST56
Regioni404 – 484DisorderedSequence analysisAdd BLAST81
Regioni589 – 690DisorderedSequence analysisAdd BLAST102

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi302 – 339Polar residuesSequence analysisAdd BLAST38
Compositional biasi404 – 473Polar residuesSequence analysisAdd BLAST70
Compositional biasi590 – 637Polar residuesSequence analysisAdd BLAST48
Compositional biasi660 – 677Polar residuesSequence analysisAdd BLAST18

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0116, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011365

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_022209_0_2_1

Identification of Orthologs from Complete Genome Data

More...OMAi		PHQIGSE

Database of Orthologous Groups

More...OrthoDBi		1526879at2759

Family and domain databases

Conserved Domains Database

More...CDDi		cd00780, NTF2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR034377, G3BP2
IPR032710, NTF2-like_dom_sf
IPR002075, NTF2_dom
IPR018222, Nuclear_transport_factor_2_euk
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR039539, Ras_GTPase_bind_prot
IPR035979, RBD_domain_sf
IPR000504, RRM_dom

The PANTHER Classification System

More...PANTHERi		PTHR10693, PTHR10693, 2 hits
PTHR10693:SF10, PTHR10693:SF10, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02136, NTF2, 1 hit
PF00076, RRM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00360, RRM, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54427, SSF54427, 1 hit
SSF54928, SSF54928, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50177, NTF2_DOMAIN, 1 hit
PS50102, RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VFT4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVMDATQSQQ PSPQSVGREF VRQYYTLLNK APNHLHRFYN HNSSYIHGES 
        60         70         80         90        100
KLVVGQREIH NRIQQLNFND CHAKISQVDA QATLGNGVVV QVTGELSNDG 
       110        120        130        140        150
QPMRRFTQTF VLAAQSPKKY YVHNDIFRYQ DLYIEDEQDG ESRSENDEEH 
       160        170        180        190        200
DVQVVGGTVD QAVQVAGDVV AQQPQQQQAP PQPQAQVVVP QQVAPVAAGG 
       210        220        230        240        250
AAPQQIFYPL PAGAAAGRPV AVLPPAPQAA AVPLPAQFTV PPPQPIQNGV 
       260        270        280        290        300
VSHEELQQQQ VLVPPSVSPL VQQQQPTGTP VLPIVPVPSA GFQQSPLVAP 
       310        320        330        340        350
QLIQQQQQQQ PAQLPPQQQQ QQQPIQQQQP LQQQQQPLAE PEEVEVAPRQ 
       360        370        380        390        400
QKPPTPVEDF KTIHEQQQQE KYEAAKQQQN EPKTYANLFK STSSSPSGFV 
       410        420        430        440        450
NAALQQQQQL QQQQQQQQSI SSNTYNSSSA TSGGGNGSQV SYSTTASSYN 
       460        470        480        490        500
NSNGNSRLDN GGPLPQRNNS IRNNKGDFEQ RRSSNTQQFG DNQQLFLGNI 
       510        520        530        540        550
PHHASEDDLR EIFSRFGNVL ELRILSKAGN KVPPGMRSPL NYGFITYDDP 
       560        570        580        590        600
EAVQKCLANC PLYFPENSPD GQKLNVEEKK PRVRNDMVPR QQIGGNNLNN 
       610        620        630        640        650
NMGRLGGNNG PQSRPMGNNN GSGGGMMRNN AGGNNLRQGG GGGNGAPRLG 
       660        670        680        690
GGGGFGQRQD NRTGGGNNQS NGPLRGAGNG QSGGGNYGRR
Length:690
Mass (Da):74,943
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i40C5AC6F9F4EB353
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54965.3
AE014297 Genomic DNA Translation: AAG22151.2
AY058617 mRNA Translation: AAL13846.1
AE014297 Genomic DNA Translation: AAN13572.1
AE014297 Genomic DNA Translation: AAN13573.1
BT011006 mRNA Translation: AAR27877.1

NCBI Reference Sequences

More...RefSeqi		NP_524907.2, NM_080168.3
NP_731828.1, NM_169531.2
NP_731829.1, NM_169532.2
NP_731830.2, NM_169533.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0082797; FBpp0082265; FBgn0015778
FBtr0082799; FBpp0082267; FBgn0015778
FBtr0346346; FBpp0312063; FBgn0015778
FBtr0346347; FBpp0312064; FBgn0015778

Database of genes from NCBI RefSeq genomes

More...GeneIDi		47998

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG9412

UCSC genome browser

More...UCSCi		CG9412-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54965.3
AE014297 Genomic DNA Translation: AAG22151.2
AY058617 mRNA Translation: AAL13846.1
AE014297 Genomic DNA Translation: AAN13572.1
AE014297 Genomic DNA Translation: AAN13573.1
BT011006 mRNA Translation: AAR27877.1
RefSeqiNP_524907.2, NM_080168.3
NP_731828.1, NM_169531.2
NP_731829.1, NM_169532.2
NP_731830.2, NM_169533.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3UJMX-ray2.74A/B15-130[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiQ9VFT4, 2 interactors
STRINGi7227.FBpp0082264

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		47998

Genome annotation databases

EnsemblMetazoaiFBtr0082797; FBpp0082265; FBgn0015778
FBtr0082799; FBpp0082267; FBgn0015778
FBtr0346346; FBpp0312063; FBgn0015778
FBtr0346347; FBpp0312064; FBgn0015778
GeneIDi47998
KEGGidme:Dmel_CG9412
UCSCiCG9412-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		47998
FlyBaseiFBgn0015778, rin
VEuPathDBiVectorBase:FBgn0015778

Phylogenomic databases

eggNOGiKOG0116, Eukaryota
GeneTreeiENSGT00390000011365
HOGENOMiCLU_022209_0_2_1
OMAiPHQIGSE
OrthoDBi1526879at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		47998, 1 hit in 3 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		rin, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		47998

Gene expression databases

BgeeiFBgn0015778, Expressed in imaginal disc and 39 other tissues

Family and domain databases

CDDicd00780, NTF2, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR034377, G3BP2
IPR032710, NTF2-like_dom_sf
IPR002075, NTF2_dom
IPR018222, Nuclear_transport_factor_2_euk
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR039539, Ras_GTPase_bind_prot
IPR035979, RBD_domain_sf
IPR000504, RRM_dom
PANTHERiPTHR10693, PTHR10693, 2 hits
PTHR10693:SF10, PTHR10693:SF10, 2 hits
PfamiView protein in Pfam
PF02136, NTF2, 1 hit
PF00076, RRM_1, 1 hit
SMARTiView protein in SMART
SM00360, RRM, 1 hit
SUPFAMiSSF54427, SSF54427, 1 hit
SSF54928, SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50177, NTF2_DOMAIN, 1 hit
PS50102, RRM, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VFT4_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VFT4
Secondary accession number(s): Q9I7J5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: January 19, 2022
This is version 176 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Proteomics identificationCombined sources, Reference proteomeImported
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