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UniProtKB - Q9VFT4 (Q9VFT4_DROME)
Protein
Submitted name:
AT27578p
Gene
rin
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- DNA helicase activity Source: FlyBase
- mRNA binding Source: GO_Central
- RNA helicase activity Source: FlyBase
GO - Biological processi
- compound eye photoreceptor fate commitment Source: FlyBase
- dorsal/ventral axis specification, ovarian follicular epithelium Source: FlyBase
- ommatidial rotation Source: FlyBase
- positive regulation of gene expression Source: FlyBase
- response to amino acid starvation Source: FlyBase
- stress granule assembly Source: FlyBase
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: AT27578pImportedSubmitted name: LD31194pImportedSubmitted name: Rasputin, isoform BImportedSubmitted name: Rasputin, isoform EImportedSubmitted name: Rasputin, isoform FImportedSubmitted name: Rasputin, isoform GImported |
Gene namesi | Name:rinImported Synonyms:cg9412Imported, Dmel\CG9412Imported, NtsImported, raspImported, RINImported, RinImported ORF Names:CG9412Imported, Dmel_CG9412Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0015778, rin |
VEuPathDBi | VectorBase:FBgn0015778 |
Subcellular locationi
Other locations
- Stress granule ARBA annotation
Cytosol
- cytosol Source: FlyBase
Nucleus
- catalytic step 2 spliceosome Source: FlyBase
- precatalytic spliceosome Source: FlyBase
Other locations
- cytoplasm Source: FlyBase
- cytoplasmic stress granule Source: FlyBase
- ribonucleoprotein complex Source: FlyBase
Expressioni
Gene expression databases
Bgeei | FBgn0015778, Expressed in imaginal disc and 39 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9VFT4, 2 interactors |
STRINGi | 7227.FBpp0082264 |
Structurei
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 129 | NTF2InterPro annotationAdd BLAST | 114 | |
Domaini | 493 – 581 | RRMInterPro annotationAdd BLAST | 89 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 302 – 357 | DisorderedSequence analysisAdd BLAST | 56 | |
Regioni | 404 – 484 | DisorderedSequence analysisAdd BLAST | 81 | |
Regioni | 589 – 690 | DisorderedSequence analysisAdd BLAST | 102 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 302 – 339 | Polar residuesSequence analysisAdd BLAST | 38 | |
Compositional biasi | 404 – 473 | Polar residuesSequence analysisAdd BLAST | 70 | |
Compositional biasi | 590 – 637 | Polar residuesSequence analysisAdd BLAST | 48 | |
Compositional biasi | 660 – 677 | Polar residuesSequence analysisAdd BLAST | 18 |
Phylogenomic databases
eggNOGi | KOG0116, Eukaryota |
GeneTreei | ENSGT00390000011365 |
HOGENOMi | CLU_022209_0_2_1 |
OMAi | PHQIGSE |
OrthoDBi | 1526879at2759 |
Family and domain databases
CDDi | cd00780, NTF2, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR034377, G3BP2 IPR032710, NTF2-like_dom_sf IPR002075, NTF2_dom IPR018222, Nuclear_transport_factor_2_euk IPR012677, Nucleotide-bd_a/b_plait_sf IPR039539, Ras_GTPase_bind_prot IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR10693, PTHR10693, 2 hits PTHR10693:SF10, PTHR10693:SF10, 2 hits |
Pfami | View protein in Pfam PF02136, NTF2, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50177, NTF2_DOMAIN, 1 hit PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VFT4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVMDATQSQQ PSPQSVGREF VRQYYTLLNK APNHLHRFYN HNSSYIHGES
60 70 80 90 100
KLVVGQREIH NRIQQLNFND CHAKISQVDA QATLGNGVVV QVTGELSNDG
110 120 130 140 150
QPMRRFTQTF VLAAQSPKKY YVHNDIFRYQ DLYIEDEQDG ESRSENDEEH
160 170 180 190 200
DVQVVGGTVD QAVQVAGDVV AQQPQQQQAP PQPQAQVVVP QQVAPVAAGG
210 220 230 240 250
AAPQQIFYPL PAGAAAGRPV AVLPPAPQAA AVPLPAQFTV PPPQPIQNGV
260 270 280 290 300
VSHEELQQQQ VLVPPSVSPL VQQQQPTGTP VLPIVPVPSA GFQQSPLVAP
310 320 330 340 350
QLIQQQQQQQ PAQLPPQQQQ QQQPIQQQQP LQQQQQPLAE PEEVEVAPRQ
360 370 380 390 400
QKPPTPVEDF KTIHEQQQQE KYEAAKQQQN EPKTYANLFK STSSSPSGFV
410 420 430 440 450
NAALQQQQQL QQQQQQQQSI SSNTYNSSSA TSGGGNGSQV SYSTTASSYN
460 470 480 490 500
NSNGNSRLDN GGPLPQRNNS IRNNKGDFEQ RRSSNTQQFG DNQQLFLGNI
510 520 530 540 550
PHHASEDDLR EIFSRFGNVL ELRILSKAGN KVPPGMRSPL NYGFITYDDP
560 570 580 590 600
EAVQKCLANC PLYFPENSPD GQKLNVEEKK PRVRNDMVPR QQIGGNNLNN
610 620 630 640 650
NMGRLGGNNG PQSRPMGNNN GSGGGMMRNN AGGNNLRQGG GGGNGAPRLG
660 670 680 690
GGGGFGQRQD NRTGGGNNQS NGPLRGAGNG QSGGGNYGRR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF54965.3 AE014297 Genomic DNA Translation: AAG22151.2 AY058617 mRNA Translation: AAL13846.1 AE014297 Genomic DNA Translation: AAN13572.1 AE014297 Genomic DNA Translation: AAN13573.1 BT011006 mRNA Translation: AAR27877.1 |
RefSeqi | NP_524907.2, NM_080168.3 NP_731828.1, NM_169531.2 NP_731829.1, NM_169532.2 NP_731830.2, NM_169533.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0082797; FBpp0082265; FBgn0015778 FBtr0082799; FBpp0082267; FBgn0015778 FBtr0346346; FBpp0312063; FBgn0015778 FBtr0346347; FBpp0312064; FBgn0015778 |
GeneIDi | 47998 |
KEGGi | dme:Dmel_CG9412 |
UCSCi | CG9412-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF54965.3 AE014297 Genomic DNA Translation: AAG22151.2 AY058617 mRNA Translation: AAL13846.1 AE014297 Genomic DNA Translation: AAN13572.1 AE014297 Genomic DNA Translation: AAN13573.1 BT011006 mRNA Translation: AAR27877.1 |
RefSeqi | NP_524907.2, NM_080168.3 NP_731828.1, NM_169531.2 NP_731829.1, NM_169532.2 NP_731830.2, NM_169533.2 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3UJM | X-ray | 2.74 | A/B | 15-130 | [»] | |
ModBasei | Search... | |||||
SWISS-MODEL-Workspacei | Submit a new modelling project... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | Q9VFT4, 2 interactors |
STRINGi | 7227.FBpp0082264 |
Protocols and materials databases
DNASUi | 47998 |
Genome annotation databases
EnsemblMetazoai | FBtr0082797; FBpp0082265; FBgn0015778 FBtr0082799; FBpp0082267; FBgn0015778 FBtr0346346; FBpp0312063; FBgn0015778 FBtr0346347; FBpp0312064; FBgn0015778 |
GeneIDi | 47998 |
KEGGi | dme:Dmel_CG9412 |
UCSCi | CG9412-RA, d. melanogaster |
Organism-specific databases
CTDi | 47998 |
FlyBasei | FBgn0015778, rin |
VEuPathDBi | VectorBase:FBgn0015778 |
Phylogenomic databases
eggNOGi | KOG0116, Eukaryota |
GeneTreei | ENSGT00390000011365 |
HOGENOMi | CLU_022209_0_2_1 |
OMAi | PHQIGSE |
OrthoDBi | 1526879at2759 |
Miscellaneous databases
BioGRID-ORCSi | 47998, 1 hit in 3 CRISPR screens |
ChiTaRSi | rin, fly |
GenomeRNAii | 47998 |
Gene expression databases
Bgeei | FBgn0015778, Expressed in imaginal disc and 39 other tissues |
Family and domain databases
CDDi | cd00780, NTF2, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR034377, G3BP2 IPR032710, NTF2-like_dom_sf IPR002075, NTF2_dom IPR018222, Nuclear_transport_factor_2_euk IPR012677, Nucleotide-bd_a/b_plait_sf IPR039539, Ras_GTPase_bind_prot IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR10693, PTHR10693, 2 hits PTHR10693:SF10, PTHR10693:SF10, 2 hits |
Pfami | View protein in Pfam PF02136, NTF2, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50177, NTF2_DOMAIN, 1 hit PS50102, RRM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VFT4_DROME | |
Accessioni | Q9VFT4Primary (citable) accession number: Q9VFT4 Secondary accession number(s): Q9I7J5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | January 19, 2022 | |
This is version 176 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |