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Entry version 165 (16 Oct 2019)
Sequence version 2 (01 Mar 2003)
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Protein
Submitted name:

Dipeptidase B, isoform A

Gene

Dip-B

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseImported

Protein family/group databases

MEROPS protease database

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MEROPSi
M17.011

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dipeptidase B, isoform AImported
Submitted name:
Dipeptidase B, isoform BImported
Submitted name:
Dipeptidase B, isoform CImported
Submitted name:
Dipeptidase B, isoform DImported (EC:3.4.14.-Imported)
Submitted name:
LD41062pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dip-BImported
Synonyms:DipBImported, Dmel\CG9285Imported
ORF Names:CG9285Imported, Dmel_CG9285Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

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FlyBasei
FBgn0000454 Dip-B

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

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PRIDEi
Q9VFQ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0000454 Expressed in 34 organ(s), highest expression level in embryonic/larval hemocyte (Drosophila)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q9VFQ9, 8 interactors

STRING: functional protein association networks

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STRINGi
7227.FBpp0082299

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini337 – 344CYTOSOL_APInterPro annotation8

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG2597 Eukaryota
COG0260 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00530000063255

KEGG Orthology (KO)

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KOi
K01255

Identification of Orthologs from Complete Genome Data

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OMAi
CMVRNSV

Database of Orthologous Groups

More...
OrthoDBi
562530at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00433 Peptidase_M17, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011356 Leucine_aapep/pepB
IPR000819 Peptidase_M17_C

The PANTHER Classification System

More...
PANTHERi
PTHR11963 PTHR11963, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00883 Peptidase_M17, 1 hit

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00481 LAMNOPPTDASE

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00631 CYTOSOL_AP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VFQ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGIEKILPCT LRLNKLMSLA GNDCLCIIDR NAVPNELKAT FEEHRKFDKS
60 70 80 90 100
FDSSISCFKV PNVDQPVVYA PVSELTDYDD VRSYQEAAKR SMEKVLKAGF
110 120 130 140 150
HTPLLFVPKV KRFPEVELCT VLGALEQLYV PIQLREAGTL KDPRVTTLSV
160 170 180 190 200
QIDDPRAEAI FQEALILEAG RFVARDIGVG DPERMTPIQV EKYIKPLFDK
210 220 230 240 250
LNVNVISDTQ VLQKEYPLFA AVNRAADAVE RHRGRIIFLE YKPPKPARKT
260 270 280 290 300
LMLVGKGVTY DTGGADIKAG GVMAGMSRDK CGAAAVAGFM QVVSQLQPDD
310 320 330 340 350
IHVVAALCMV RNSVGEECYV ADEVITSRAG LHVRIGNTDA EGRMCMTDAL
360 370 380 390 400
CRMKELVVEQ NLPDPHLFTI ATLTGHAFIS AGEGQSIAID NSVAHREDHA
410 420 430 440 450
RRLQAAGQAF GEPFEVSILR PSDFSFNAGK VIGEDLVQAN NAPSVRTPRG
460 470 480 490 500
HQVPAAFMIK ASGLDKHGLD SMLPIKYTHI DIAGSAGEHP AMPTAAPLVS

LVKTHLQK
Length:508
Mass (Da):55,534
Last modified:March 1, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i77D54D078312922F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54991.2
AY051926 mRNA Translation: AAK93350.1
AE014297 Genomic DNA Translation: AAN13593.1
AE014297 Genomic DNA Translation: AAN13594.1
AE014297 Genomic DNA Translation: AHN57315.1

NCBI Reference Sequences

More...
RefSeqi
NP_001287316.1, NM_001300387.1
NP_650318.1, NM_142061.3
NP_731863.1, NM_169557.2
NP_731864.1, NM_169558.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0082831; FBpp0082299; FBgn0000454
FBtr0082832; FBpp0082300; FBgn0000454
FBtr0082833; FBpp0082301; FBgn0000454
FBtr0345229; FBpp0311421; FBgn0000454

Database of genes from NCBI RefSeq genomes

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GeneIDi
48450

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG9285

UCSC genome browser

More...
UCSCi
CG9285-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF54991.2
AY051926 mRNA Translation: AAK93350.1
AE014297 Genomic DNA Translation: AAN13593.1
AE014297 Genomic DNA Translation: AAN13594.1
AE014297 Genomic DNA Translation: AHN57315.1
RefSeqiNP_001287316.1, NM_001300387.1
NP_650318.1, NM_142061.3
NP_731863.1, NM_169557.2
NP_731864.1, NM_169558.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9VFQ9, 8 interactors
STRINGi7227.FBpp0082299

Protein family/group databases

MEROPSiM17.011

Proteomic databases

PRIDEiQ9VFQ9

Genome annotation databases

EnsemblMetazoaiFBtr0082831; FBpp0082299; FBgn0000454
FBtr0082832; FBpp0082300; FBgn0000454
FBtr0082833; FBpp0082301; FBgn0000454
FBtr0345229; FBpp0311421; FBgn0000454
GeneIDi48450
KEGGidme:Dmel_CG9285
UCSCiCG9285-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
48450
FlyBaseiFBgn0000454 Dip-B

Phylogenomic databases

eggNOGiKOG2597 Eukaryota
COG0260 LUCA
GeneTreeiENSGT00530000063255
KOiK01255
OMAiCMVRNSV
OrthoDBi562530at2759

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
48450

Gene expression databases

BgeeiFBgn0000454 Expressed in 34 organ(s), highest expression level in embryonic/larval hemocyte (Drosophila)

Family and domain databases

CDDicd00433 Peptidase_M17, 1 hit
InterProiView protein in InterPro
IPR011356 Leucine_aapep/pepB
IPR000819 Peptidase_M17_C
PANTHERiPTHR11963 PTHR11963, 1 hit
PfamiView protein in Pfam
PF00883 Peptidase_M17, 1 hit
PRINTSiPR00481 LAMNOPPTDASE
PROSITEiView protein in PROSITE
PS00631 CYTOSOL_AP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VFQ9_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VFQ9
Secondary accession number(s): Q960P8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: March 1, 2003
Last modified: October 16, 2019
This is version 165 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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