UniProtKB - Q9VFJ2 (RM11_DROME)
Protein
39S ribosomal protein L11, mitochondrial
Gene
mRpL11
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- large ribosomal subunit rRNA binding Source: GO_Central
- rRNA binding Source: GO_Central
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- gene silencing by RNA Source: UniProtKB-KW
- mitochondrial translation Source: FlyBase
- regulation of translation Source: UniProtKB-KW
- ribosomal large subunit assembly Source: GO_Central
- translation Source: GO_Central
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Biological process | RNA-mediated gene silencing, Translation regulation |
Enzyme and pathway databases
Reactomei | R-DME-5389840, Mitochondrial translation elongation R-DME-5419276, Mitochondrial translation termination |
Names & Taxonomyi
Protein namesi | Recommended name: 39S ribosomal protein L11, mitochondrialShort name: L11mt Short name: MRP-L11 |
Gene namesi | Name:mRpL11 ORF Names:CG3351 |
Organismi | Drosophila melanogaster (Fruit fly) |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0038234, mRpL11 |
Subcellular locationi
Mitochondrion
- Mitochondrion By similarity
Mitochondrion
- mitochondrial large ribosomal subunit Source: UniProtKB
Other locations
- large ribosomal subunit Source: GO_Central
- ribosome Source: GO_Central
Keywords - Cellular componenti
MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – ? | MitochondrionSequence analysis | ||
ChainiPRO_0000030446 | ? – 196 | 39S ribosomal protein L11, mitochondrial |
Proteomic databases
PaxDbi | Q9VFJ2 |
PRIDEi | Q9VFJ2 |
Expressioni
Gene expression databases
Bgeei | FBgn0038234, Expressed in embryo and 20 other tissues |
Genevisiblei | Q9VFJ2, DM |
Interactioni
Subunit structurei
Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.
By similarityProtein-protein interaction databases
BioGRIDi | 66832, 1 interactor |
DIPi | DIP-23522N |
IntActi | Q9VFJ2, 3 interactors |
STRINGi | 7227.FBpp0082412 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL11 family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG3257, Eukaryota |
GeneTreei | ENSGT00390000003153 |
HOGENOMi | CLU_074237_1_1_1 |
InParanoidi | Q9VFJ2 |
OMAi | CKQFNAK |
OrthoDBi | 1346532at2759 |
PhylomeDBi | Q9VFJ2 |
Family and domain databases
CDDi | cd00349, Ribosomal_L11, 1 hit |
Gene3Di | 1.10.10.250, 1 hit 3.30.1550.10, 1 hit |
HAMAPi | MF_00736, Ribosomal_L11, 1 hit |
InterProi | View protein in InterPro IPR000911, Ribosomal_L11/L12 IPR036796, Ribosomal_L11/L12_N_sf IPR020783, Ribosomal_L11_C IPR036769, Ribosomal_L11_C_sf IPR020784, Ribosomal_L11_N |
PANTHERi | PTHR11661, PTHR11661, 1 hit |
Pfami | View protein in Pfam PF00298, Ribosomal_L11, 1 hit PF03946, Ribosomal_L11_N, 1 hit |
SMARTi | View protein in SMART SM00649, RL11, 1 hit |
SUPFAMi | SSF46906, SSF46906, 1 hit SSF54747, SSF54747, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9VFJ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKAAGKLKS LKKTVERVTH TSKLKTNIPA GMAAAGPPLG PMLGQRAINI
60 70 80 90 100
AAFCKDFNAK TAEMKEGVPL PCRISVNSDR SYDLAIHHPP ATFFLKQAAG
110 120 130 140 150
IQRGTMTPGK EVAGMITLKH LYEIAAIKIQ DPPNVLLTMQ QMCEMLISIA
160 170 180 190
RTCGIKVVRE IDPAAYGEFL EERKLIVEQQ RRELQEKREA KMLRTG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF55063.1 AY094892 mRNA Translation: AAM11245.1 |
RefSeqi | NP_524351.1, NM_079627.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0082953; FBpp0082412; FBgn0038234 |
GeneIDi | 41757 |
KEGGi | dme:Dmel_CG3351 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF55063.1 AY094892 mRNA Translation: AAM11245.1 |
RefSeqi | NP_524351.1, NM_079627.3 |
3D structure databases
SMRi | Q9VFJ2 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 66832, 1 interactor |
DIPi | DIP-23522N |
IntActi | Q9VFJ2, 3 interactors |
STRINGi | 7227.FBpp0082412 |
Proteomic databases
PaxDbi | Q9VFJ2 |
PRIDEi | Q9VFJ2 |
Genome annotation databases
EnsemblMetazoai | FBtr0082953; FBpp0082412; FBgn0038234 |
GeneIDi | 41757 |
KEGGi | dme:Dmel_CG3351 |
Organism-specific databases
CTDi | 65003 |
FlyBasei | FBgn0038234, mRpL11 |
Phylogenomic databases
eggNOGi | KOG3257, Eukaryota |
GeneTreei | ENSGT00390000003153 |
HOGENOMi | CLU_074237_1_1_1 |
InParanoidi | Q9VFJ2 |
OMAi | CKQFNAK |
OrthoDBi | 1346532at2759 |
PhylomeDBi | Q9VFJ2 |
Enzyme and pathway databases
Reactomei | R-DME-5389840, Mitochondrial translation elongation R-DME-5419276, Mitochondrial translation termination |
Miscellaneous databases
BioGRID-ORCSi | 41757, 1 hit in 1 CRISPR screen |
GenomeRNAii | 41757 |
PROi | PR:Q9VFJ2 |
Gene expression databases
Bgeei | FBgn0038234, Expressed in embryo and 20 other tissues |
Genevisiblei | Q9VFJ2, DM |
Family and domain databases
CDDi | cd00349, Ribosomal_L11, 1 hit |
Gene3Di | 1.10.10.250, 1 hit 3.30.1550.10, 1 hit |
HAMAPi | MF_00736, Ribosomal_L11, 1 hit |
InterProi | View protein in InterPro IPR000911, Ribosomal_L11/L12 IPR036796, Ribosomal_L11/L12_N_sf IPR020783, Ribosomal_L11_C IPR036769, Ribosomal_L11_C_sf IPR020784, Ribosomal_L11_N |
PANTHERi | PTHR11661, PTHR11661, 1 hit |
Pfami | View protein in Pfam PF00298, Ribosomal_L11, 1 hit PF03946, Ribosomal_L11_N, 1 hit |
SMARTi | View protein in SMART SM00649, RL11, 1 hit |
SUPFAMi | SSF46906, SSF46906, 1 hit SSF54747, SSF54747, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RM11_DROME | |
Accessioni | Q9VFJ2Primary (citable) accession number: Q9VFJ2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 26, 2002 |
Last sequence update: | May 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - Drosophila
Drosophila: entries, gene names and cross-references to FlyBase - SIMILARITY comments
Index of protein domains and families