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Entry version 136 (26 Feb 2020)
Sequence version 2 (07 Feb 2006)
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Protein

Protein kibra

Gene

kibra

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signaling pathway.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-2028269 Signaling by Hippo

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9VFG8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein kibra
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:kibra
ORF Names:CG33967
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0262127 kibra

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Homozygous embryonic lethality, oogenesis defects, tissue overgrowth characterized by excessive cell proliferation and diminished apoptosis.3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003929711 – 1288Protein kibraAdd BLAST1288

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei992Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VFG8

PRoteomics IDEntifications database

More...
PRIDEi
Q9VFG8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9VFG8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in ovarian posterior follicle cells and wing disks (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0262127 Expressed in oviduct (Drosophila) and 27 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VFG8 differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VFG8 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a complex with Mer and Ex.

Interacts (via domain WW 1) with Ex (via RXPPXY motif).

Interacts with Mer, Sav, Hpo and Wts.

3 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
66857, 26 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VFG8, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0099467

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VFG8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini54 – 87WW 1PROSITE-ProRule annotationAdd BLAST34
Domaini101 – 134WW 2PROSITE-ProRule annotationAdd BLAST34
Domaini693 – 795C2Add BLAST103

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili201 – 229Sequence analysisAdd BLAST29
Coiled coili335 – 463Sequence analysisAdd BLAST129
Coiled coili1049 – 1076Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi5 – 49Gln-richAdd BLAST45
Compositional biasi13 – 51His-richAdd BLAST39
Compositional biasi190 – 196Poly-Ser7
Compositional biasi533 – 536Poly-Gln4
Compositional biasi832 – 841Poly-Ala10
Compositional biasi899 – 904Poly-Asp6
Compositional biasi905 – 908Poly-Glu4
Compositional biasi1166 – 1176Poly-GluAdd BLAST11
Compositional biasi1224 – 1271Ala-richAdd BLAST48

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WWC family. KIBRA subfamily.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0940 Eukaryota
KOG3209 Eukaryota
ENOG410XSXK LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00410000025556

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005420_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VFG8

KEGG Orthology (KO)

More...
KOi
K16685

Identification of Orthologs from Complete Genome Data

More...
OMAi
HHTHIPR

Database of Orthologous Groups

More...
OrthoDBi
364990at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VFG8

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08680 C2_Kibra, 1 hit
cd00201 WW, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR037771 C2_WWC
IPR001202 WW_dom
IPR036020 WW_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168 C2, 1 hit
PF00397 WW, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239 C2, 1 hit
SM00456 WW, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51045 SSF51045, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VFG8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPNLQQTASQ SQHHLHPHHL RPQQQQQQHH HHHQQQQQQQ HTHHQQQQQH
60 70 80 90 100
HSDFPLPDGW DIAKDFDGKT YYIDHINKKT TWLDPRDCYT KPQTFEDCVG
110 120 130 140 150
DELPMGWEES YDPNIGPYYI NHLAQSTQLE DPRQEWKTVQ EQMLSDYLSA
160 170 180 190 200
AQDQLENKRE MFDVKQQRLL WAQEEYNHLK LAASRSSLCS SSSSMSRHDP
210 220 230 240 250
ELLRADLMLA RERVHQLKQE LTHITNDISY TERGMNTLYS VGEKINAREN
260 270 280 290 300
GCYDIAEVHA IREEMLKVHK SLVSGEKVRE ELMRSLVQIK NELGRQQISE
310 320 330 340 350
ENSDLASPFD RVCVASQTDL CGSSGENLNG GARFAEMAKT KWQYAEWRKH
360 370 380 390 400
IKKLQQQLAD HVERIEPGQL ESDKDRILLI QEKEKLLNDL NSISLKSRSE
410 420 430 440 450
EEKRVIHQTR HKLEEDLKEA YEANNTCVAN RLRFHEEKQL LLDKLQEALK
460 470 480 490 500
STKLLEERLK SFSSESTFSI SSGSSLGSLS TASSKSALSF TDIYIDPFAV
510 520 530 540 550
DSPIDVVDLR RRSQRLFQQH QQQRLHPVHP VLQQQQSAEV TLSPRSSLSM
560 570 580 590 600
ETPPASPMKY NAGADQTPQA LKEEPTYANA LPAPPAYTAP PPVPISGVRA
610 620 630 640 650
RPYDLDSTVL DCMMLEAKLQ KLNMGTPLNL AVAPLSPISE KPSLLDLPQE
660 670 680 690 700
MLSRSSSTSN TRSVSAAVSN ESVAGDSGVF EASRAHLPRK ELAQVQIGLK
710 720 730 740 750
YLKQEGVLVV SLERANNLLA LWTASADNSQ VYLRAALLPN SLTSIRTKAL
760 770 780 790 800
GDFQKPVFND TFAVPITLDK LLTKSLQVTV VTMTGQKEEI IGTVQISMAE
810 820 830 840 850
FNPEDSTLKW YNVLSSKFIP SFESLDIPST SAAAAAAAVA ASNAPNPGNN
860 870 880 890 900
REESSDESTI TSSQTSTLTR NQAPCMELQE QMAAELLGLG PLNEPECSDD
910 920 930 940 950
DDDDEEEELD DKQLVSDVGL MNSSSMLHAY LQNMKQEFAD KETNTDRAYL
960 970 980 990 1000
PEKSRGQSQL MDDRPVKRSQ TFTPSEAFSK NRYNCRLNRS DSDSAMHCGV
1010 1020 1030 1040 1050
APHTFQRGAA ERRSLRFHSK APKSVTKLHH THIPRTSLDL ELDLQAQHSK
1060 1070 1080 1090 1100
LYFLNDQIAK LQNLKEVLQK ACENKDPLVA AWAIENEEFQ RLVARADPAK
1110 1120 1130 1140 1150
CPEERQLQKL LMKTAKEIHK LRKTKVPKGC PDLVSFKEKI TFFTRKGLSV
1160 1170 1180 1190 1200
PELPSEFTLP EANPIEEEEE EEDENEFYNS AETAIAINTA LVASSNRNKN
1210 1220 1230 1240 1250
LSEHPHRATS GAVPKIPAPV VTPAATPAAT PAATPAATSA ATPAATPVVS
1260 1270 1280
PAAQPDAKPA DAPIPVASND AEQQRFDYVV DRNYGVEV
Length:1,288
Mass (Da):144,350
Last modified:February 7, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC450A07D640D6492
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4LH59A0A0B4LH59_DROME
Kibra, isoform B
kibra CG12600, CG7552, Dmel\CG33967, DmKibra, Kbr
1,288Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti230Y → C in AAX33444 (PubMed:12537569).Curated1
Sequence conflicti743T → A in AAX33444 (PubMed:12537569).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55090.2
BT021296 mRNA Translation: AAX33444.1

NCBI Reference Sequences

More...
RefSeqi
NP_001034055.1, NM_001038966.2
NP_001287329.1, NM_001300400.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0100008; FBpp0099467; FBgn0262127
FBtr0344383; FBpp0310756; FBgn0262127

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
41783

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG33967

UCSC genome browser

More...
UCSCi
CG33967-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55090.2
BT021296 mRNA Translation: AAX33444.1
RefSeqiNP_001034055.1, NM_001038966.2
NP_001287329.1, NM_001300400.1

3D structure databases

SMRiQ9VFG8
ModBaseiSearch...

Protein-protein interaction databases

BioGridi66857, 26 interactors
IntActiQ9VFG8, 1 interactor
STRINGi7227.FBpp0099467

PTM databases

iPTMnetiQ9VFG8

Proteomic databases

PaxDbiQ9VFG8
PRIDEiQ9VFG8

Genome annotation databases

EnsemblMetazoaiFBtr0100008; FBpp0099467; FBgn0262127
FBtr0344383; FBpp0310756; FBgn0262127
GeneIDi41783
KEGGidme:Dmel_CG33967
UCSCiCG33967-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
41783
FlyBaseiFBgn0262127 kibra

Phylogenomic databases

eggNOGiKOG0940 Eukaryota
KOG3209 Eukaryota
ENOG410XSXK LUCA
GeneTreeiENSGT00410000025556
HOGENOMiCLU_005420_1_0_1
InParanoidiQ9VFG8
KOiK16685
OMAiHHTHIPR
OrthoDBi364990at2759
PhylomeDBiQ9VFG8

Enzyme and pathway databases

ReactomeiR-DME-2028269 Signaling by Hippo
SignaLinkiQ9VFG8

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
kibra fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
41783

Protein Ontology

More...
PROi
PR:Q9VFG8

Gene expression databases

BgeeiFBgn0262127 Expressed in oviduct (Drosophila) and 27 other tissues
ExpressionAtlasiQ9VFG8 differential
GenevisibleiQ9VFG8 DM

Family and domain databases

CDDicd08680 C2_Kibra, 1 hit
cd00201 WW, 2 hits
Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR037771 C2_WWC
IPR001202 WW_dom
IPR036020 WW_dom_sf
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF00397 WW, 2 hits
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00456 WW, 2 hits
SUPFAMiSSF51045 SSF51045, 2 hits
PROSITEiView protein in PROSITE
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKIBRA_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VFG8
Secondary accession number(s): Q5BIC8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: February 7, 2006
Last modified: February 26, 2020
This is version 136 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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