UniProtKB - Q9VEQ2 (Q9VEQ2_DROME)
Protein
ER membrane protein complex subunit 2
Gene
EMC2B
Organism
Drosophila melanogaster (Fruit fly)
Status
Names & Taxonomyi
Protein namesi | Recommended name: ER membrane protein complex subunit 2UniRule annotation |
Gene namesi | ORF Names:CG3678Imported, Dmel_CG3678Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0038461, EMC2B |
Subcellular locationi
Endoplasmic reticulum
- ER membrane protein complex Source: GO_Central
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotationInteractioni
Subunit structurei
Component of the ER membrane protein complex (EMC).
UniRule annotationARBA annotationBinary interactionsi
Q9VEQ2
With | #Exp. | IntAct |
---|---|---|
EMC8-9 [Q9W1Y1] | 3 | EBI-101183,EBI-189387 |
Protein-protein interaction databases
IntActi | Q9VEQ2, 3 interactors |
STRINGi | 7227.FBpp0082819 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 85 – 223 | TPR_REGIONInterPro annotationAdd BLAST | 139 |
Sequence similaritiesi
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
eggNOGi | KOG3060, Eukaryota |
GeneTreei | ENSGT00390000011922 |
HOGENOMi | CLU_052388_1_0_1 |
OMAi | YILTCAE |
OrthoDBi | 956854at2759 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR039856, EMC2-like IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
PANTHERi | PTHR12760, PTHR12760, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 3 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50293, TPR_REGION, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VEQ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLDYEKMSW SDVRDQFRTW REETGRHSEE VVQLWVAVLE DKVHKTGNER
60 70 80 90 100
HLILEQVIIA ALDTARFDIA TKCTKQLALE FPGSLRVMKF KAMRYEALEQ
110 120 130 140 150
YDEADEVLDA IIAKDETNAA PRKRKIAILK ARGRRLEAIK ELNEYLKKFM
160 170 180 190 200
SDQEAWHELC NMYLAEGEFG KAAFCMEEVL LHNPHSHLIH QRLAEIRYTM
210 220 230 240 250
GGVENMESAR TYYSQALKLN PHNLRALYGI YLCCNHLDNS RAVSSKRKEL
260 270 280
QKLSQWALEQ LLTKQTIVPL EAAFGNLEIK SN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF55369.2 BT120319 mRNA Translation: ADC54210.1 AE014297 Genomic DNA Translation: AGB96031.1 |
RefSeqi | NP_001262651.1, NM_001275722.1 NP_650580.1, NM_142323.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0083376; FBpp0082819; FBgn0038461 FBtr0337064; FBpp0307993; FBgn0038461 |
GeneIDi | 42045 |
KEGGi | dme:Dmel_CG3678 |
UCSCi | CG3678-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF55369.2 BT120319 mRNA Translation: ADC54210.1 AE014297 Genomic DNA Translation: AGB96031.1 |
RefSeqi | NP_001262651.1, NM_001275722.1 NP_650580.1, NM_142323.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9VEQ2, 3 interactors |
STRINGi | 7227.FBpp0082819 |
Genome annotation databases
EnsemblMetazoai | FBtr0083376; FBpp0082819; FBgn0038461 FBtr0337064; FBpp0307993; FBgn0038461 |
GeneIDi | 42045 |
KEGGi | dme:Dmel_CG3678 |
UCSCi | CG3678-RA, d. melanogaster |
Organism-specific databases
CTDi | 42045 |
FlyBasei | FBgn0038461, EMC2B |
Phylogenomic databases
eggNOGi | KOG3060, Eukaryota |
GeneTreei | ENSGT00390000011922 |
HOGENOMi | CLU_052388_1_0_1 |
OMAi | YILTCAE |
OrthoDBi | 956854at2759 |
Miscellaneous databases
BioGRID-ORCSi | 42045, 0 hits in 1 CRISPR screen |
GenomeRNAii | 42045 |
Gene expression databases
Bgeei | FBgn0038461, Expressed in embryo and 18 other tissues |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR039856, EMC2-like IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
PANTHERi | PTHR12760, PTHR12760, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 3 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50293, TPR_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VEQ2_DROME | |
Accessioni | Q9VEQ2Primary (citable) accession number: Q9VEQ2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | March 1, 2003 | |
Last modified: | February 10, 2021 | |
This is version 169 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |