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Protein
Submitted name:

Cadmus, isoform A

Gene

cdm

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • modulation of chemical synaptic transmission Source: FlyBase
  • neuron-neuron synaptic transmission Source: FlyBase
  • phototaxis Source: FlyBase
  • protein import into nucleus Source: GO_Central

Names & Taxonomyi

Protein namesi
Submitted name:
Cadmus, isoform AImported
Submitted name:
Cadmus, isoform BImported
Submitted name:
LD35896pImported
Gene namesi
Name:cdmImported
Synonyms:3R23Imported, CG 7212Imported, Dmel\CG7212Imported, Imp13Imported, imp13Imported, sd-5Imported
ORF Names:CG7212Imported, Dmel_CG7212Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0261532 cdm

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiFBgn0261532 Expressed in 25 organ(s), highest expression level in embryo

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

ComplexPortaliCPX-3170 cdm-RanGTP complex
CPX-3171 cdm-mago-Y14 complex
STRINGi7227.FBpp0083039

Structurei

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 93Importin N-terminalInterPro annotationAdd BLAST67

Phylogenomic databases

eggNOGiKOG2022 Eukaryota
ENOG410XT8Y LUCA
GeneTreeiENSGT00530000063347
OMAiMLGQMYS
OrthoDBiEOG091G01CP

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR013598 Exportin-1/Importin-b-like
IPR001494 Importin-beta_N
PfamiView protein in Pfam
PF03810 IBN_N, 1 hit
PF08389 Xpo1, 1 hit
SMARTiView protein in SMART
SM00913 IBN_N, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50166 IMPORTIN_B_NT, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VEC5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPIDIARLE EAVVSFYRSN SQNQAITHEW LTDAEASPQA WQFSWQLMQL
60 70 80 90 100
GKSQEVQFFG AITLHSKLMK HWHEVPPENR EELKQKILES IVRFAGGPKI
110 120 130 140 150
VLNRLCISLG AYIVHMLGEW PGAIEEVINT FQNQRMPNVS ADVQLWIMLE
160 170 180 190 200
VLTAIPEEAQ VIHTSVKRVV LRAEIAKRVQ LVIHTVERYL KLQMNRVWDA
210 220 230 240 250
EAYSNMNRAV KCVGTWIKNI GYTIEGCVTI TAVLLEVVHK CYWPCIHAGD
260 270 280 290 300
GCMTADENEL AESCLKTMVN IIIQPDCHNY PKTAFVLIKM FLDSLSEITK
310 320 330 340 350
TEWKRENDNE DIIVHIYMLF VSSVERHSTL LLSGITSADP ELSILVHRIV
360 370 380 390 400
QEILHCTDKP GIYPVEESCS TMALAFWYML QDEVFAMSND EQKHKCWEYI
410 420 430 440 450
KPLYAHLTRI LVRKSEQPDE KSLAKWSSDD LECFRCYRQD ISDTFMYCYD
460 470 480 490 500
VLNDYILEIL AAMLDEAIAD LQRHPTHWTK LEACIYSFQS VAEHFGGEEK
510 520 530 540 550
RQIPRLMRVL AEIPYEKLNV KLLGTALETM GSYCNWLMEN PAYIPPAINL
560 570 580 590 600
LVRGLNSSMS AQATLGLKEL CRDCQLQLKP YADPLLNACH ASLNTGRMKN
610 620 630 640 650
SDSVRLMFSI GKLMSLLRPE EIPKYLDIIV SPCFEELQAI CQADSKTPAA
660 670 680 690 700
RIRTIFRLNM ISTLFSSLNT DVDEQATDQP IVQPVLLVMQ RTMPIFKRIA
710 720 730 740 750
EMWVEEIDVL EAACSAMKHA ITNLRSSFQP MLQDLCLFIV ASFQTRCCAP
760 770 780 790 800
TLEISKTAIV MFFKDEGCKP LMQQLLREFI QHSFKLFEST PEQNFSNISD
810 820 830 840 850
TMETFFGCLT QIIKKIPQVL EDKTLAYDRL VFYAQRGMTL PESGAIRNSI
860 870 880 890 900
QFLTHFVMQS RNHAHVTEVV LATGEQTLYT AMMCVGYLTP RSQVDKFADI
910 920 930 940 950
LLAMNRKYAA EMAVWMKSLM STPNFPTQLI TDADKTRYTA LIIKEKVNKR
960 970
LLQQHLSEMA MKTRGLTEKF Q
Length:971
Mass (Da):111,313
Last modified:May 1, 2000 - v1
Checksum:i79479AC06DCCF35E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55502.1
AY061428 mRNA Translation: AAL28976.1
AE014297 Genomic DNA Translation: AGB96076.1
RefSeqiNP_001262696.1, NM_001275767.1
NP_650682.1, NM_142425.3
UniGeneiDm.7262

Genome annotation databases

EnsemblMetazoaiFBtr0083619; FBpp0083039; FBgn0261532
FBtr0336472; FBpp0307575; FBgn0261532
GeneIDi42171
KEGGidme:Dmel_CG7212
UCSCiCG7212-RA d. melanogaster

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55502.1
AY061428 mRNA Translation: AAL28976.1
AE014297 Genomic DNA Translation: AGB96076.1
RefSeqiNP_001262696.1, NM_001275767.1
NP_650682.1, NM_142425.3
UniGeneiDm.7262

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2X1GX-ray3.35F/G1-971[»]
3ZKVX-ray3.00A1-971[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-3170 cdm-RanGTP complex
CPX-3171 cdm-mago-Y14 complex
STRINGi7227.FBpp0083039

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0083619; FBpp0083039; FBgn0261532
FBtr0336472; FBpp0307575; FBgn0261532
GeneIDi42171
KEGGidme:Dmel_CG7212
UCSCiCG7212-RA d. melanogaster

Organism-specific databases

CTDi12582
FlyBaseiFBgn0261532 cdm

Phylogenomic databases

eggNOGiKOG2022 Eukaryota
ENOG410XT8Y LUCA
GeneTreeiENSGT00530000063347
OMAiMLGQMYS
OrthoDBiEOG091G01CP

Miscellaneous databases

GenomeRNAii42171

Gene expression databases

BgeeiFBgn0261532 Expressed in 25 organ(s), highest expression level in embryo

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR013598 Exportin-1/Importin-b-like
IPR001494 Importin-beta_N
PfamiView protein in Pfam
PF03810 IBN_N, 1 hit
PF08389 Xpo1, 1 hit
SMARTiView protein in SMART
SM00913 IBN_N, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50166 IMPORTIN_B_NT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VEC5_DROME
AccessioniPrimary (citable) accession number: Q9VEC5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 10, 2018
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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