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Entry version 152 (17 Jun 2020)
Sequence version 2 (01 Mar 2003)
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Protein

Chromatin-remodeling ATPase INO80

Gene

Ino80

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part of the INO80 complex, remodels chromatin by shifting nucleosomes.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi560 – 567ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Hydrolase
Biological processDNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-5689603 UCH proteinases
R-DME-5696394 DNA Damage Recognition in GG-NER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chromatin-remodeling ATPase INO80Curated (EC:3.6.4.-By similarity)
Short name:
dINO80
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ino801 PublicationImported
ORF Names:CG31212Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0086613 Ino80

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003063801 – 1638Chromatin-remodeling ATPase INO80Add BLAST1638

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei47Phosphoserine1 Publication1
Modified residuei48Phosphoserine1 Publication1
Modified residuei52Phosphothreonine1 Publication1
Modified residuei67Phosphoserine1 Publication1
Modified residuei70Phosphoserine1 Publication1
Modified residuei227Phosphoserine1 Publication1
Modified residuei230Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VDY1

PRoteomics IDEntifications database

More...
PRIDEi
Q9VDY1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9VDY1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0086613 Expressed in embryo and 25 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VDY1 differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VDY1 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the chromatin remodeling Ino80 complex.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
67311, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VDY1, 388 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0083185

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VDY1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini313 – 438DBINOPROSITE-ProRule annotationAdd BLAST126
Domaini547 – 718Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST172
Domaini1160 – 1315Helicase C-terminalPROSITE-ProRule annotationAdd BLAST156

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili136 – 161Sequence analysisAdd BLAST26

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The DBINO region is involved in binding to DNA.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family.Sequence analysis

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0388 Eukaryota
ENOG410XP0A LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00900000141110

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000315_19_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VDY1

KEGG Orthology (KO)

More...
KOi
K11665

Identification of Orthologs from Complete Genome Data

More...
OMAi
NTMAEVR

Database of Orthologous Groups

More...
OrthoDBi
188211at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VDY1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020838 DBINO
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR031047 Ino80
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N

The PANTHER Classification System

More...
PANTHERi
PTHR45685:SF2 PTHR45685:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13892 DBINO, 1 hit
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51413 DBINO, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VDY1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEAKPVPAPQ PRPRAMAEPL HIQRLEAALN MRPFMNMAKR SLRKPLSSDE
60 70 80 90 100
ETDDEHVVKR EHDVQDSDDS STVGVVRMKQ SSKRKSRLLA SKEERQSVKA
110 120 130 140 150
QLYNFNDLTS DREWLYDLLL SDTESDDPTI TEDEYVQQLL REHVREQRQR
160 170 180 190 200
KNYYKKAANA QYAYYGSGLL SNHDIFAERQ LATAGVRKRR RRTKQEILMA
210 220 230 240 250
RLAEAQAGPK PPKQRRRGRK KRDNMGSPES GEVPPSELGK YTFGDTLPNN
260 270 280 290 300
EDDDEDGGEV DYKRELASLA LDYPEEEEIE EEVDVEGGTE GQVTKVRRKR
310 320 330 340 350
KNPAALAARR RRIWQIMSKK ESGRLQRIKS NNHKEMLANC KRVAGMCAKV
360 370 380 390 400
VRQRAINSQR IMKETVWRAK RLTREMLAYW KRYERVERDQ RRKQEREAEE
410 420 430 440 450
QRKQDVELIE VKRQQRKLNF LITQTELYAH FMSKKLGQGS EEDQLRILSQ
460 470 480 490 500
LDEETNARLA AQDDYDAGEM KLLAQENAEA AMQRDLDKTR AFDVFAKKKE
510 520 530 540 550
KEEEEQAQES VEDIKPEPRP EMKDLPQPKM FKGTLKGYQI KGMTWLANIY
560 570 580 590 600
DQGISGILAD EMGLGKTVQS IAFLCHIAEH YGVWGPFLVI SPASTLHNWQ
610 620 630 640 650
QEMSRFVPDF KVVPYWGSPA ERKILRQFWD QKHLHTRDAS FHVVITSYQL
660 670 680 690 700
VVSDYKYFNR IKWQYMVLDE AQAIKSAASQ RWKLLLGFSC RNRLLLSGTP
710 720 730 740 750
IQNSMAELWA LLHFIMPTLF DSHDEFNEWF SKDIESHAEN KTGIDEKQIS
760 770 780 790 800
RLHMILKPFM LRRIKKDVEN ELSDKIEIMV YCPLTIRQKL LYRALKQKIR
810 820 830 840 850
IEDLLHLTSG STTTSSSSSA SNLMNLVMQF RKVCNHPELF ERRDARSPFF
860 870 880 890 900
MRCAEYTIPR LIHEEGLIHR MLPSRKHLLY NRFNIFKSEY IQRSLFEDVN
910 920 930 940 950
VNSCFGFTRL CDLSVGDMVE VTLNGLIDFL LHYRRVLEKY PLLAYRRFWW
960 970 980 990 1000
KKQPDSRYQL LEPMLENKLA LDYMPPNSVL KNFIFTAMTA NESSVYAFGD
1010 1020 1030 1040 1050
YFTYNMQETI EHRVIRSKIL KKKTSLIEEM EDVSKQKLEI ESVEVQTKSN
1060 1070 1080 1090 1100
AKSDVKVTTL LLLPEFPHRP RKPRKYVCEP LSMPRILYDL GQKVQAVHRY
1110 1120 1130 1140 1150
LYCDSRSAAW SQIRHNQCEN SQGRELVSSG LALCKPHGGW SSIVVPDKET
1160 1170 1180 1190 1200
LITDAGKLFV LDNLLTRLKA NGHRVLIYSQ MTKMIDLLEE YMWHRKHRYM
1210 1220 1230 1240 1250
RLDGSSKISA RRDMVADFQT RADIFVFLLS TRAGGLGINL TAADTVIFYD
1260 1270 1280 1290 1300
SDWNPTVDQQ AMDRAHRLGQ TKQVTVYRLI CKGTIEERIL QRAREKSEIQ
1310 1320 1330 1340 1350
RMVISGGNFK PDTLKPKEVV SLLLDDEEIE MKYRQEAKLQ SSSPIPAATQ
1360 1370 1380 1390 1400
SERKRRHPQK DVNMGGTTIA ATSATQNPDD DVPSCSSAAK RIKLETEEDF
1410 1420 1430 1440 1450
IDVGITSSAS SVGTDSNHPT LSQETYVPGA TCVQQTEIDS ENEALVVDGD
1460 1470 1480 1490 1500
SPTMLGQNES MNFLDDLSGI SPMRRRHHPR GTRRGRPRGS TRRGGGHGSI
1510 1520 1530 1540 1550
PRVLTPTQAA TPAVPATASQ AAAAGTGAAA GTSSPLPQQE VSGGGDNAGV
1560 1570 1580 1590 1600
PLHEEEYRTS PSGQSPGVSC KRGPGRPRSK TATPISRGTR GAPRARRPMG
1610 1620 1630
PLLVPLGRSP DDTPPSSSPA TSRAPSPLSG SHGAVGPE
Length:1,638
Mass (Da):187,086
Last modified:March 1, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB9D8BB664644512B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1628 – 1629LS → SA in AAL39931 (PubMed:12537569).Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55658.2
AY069786 mRNA Translation: AAL39931.1

NCBI Reference Sequences

More...
RefSeqi
NP_732413.1, NM_169854.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0083771; FBpp0083185; FBgn0086613

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42314

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG31212

UCSC genome browser

More...
UCSCi
CG31212-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55658.2
AY069786 mRNA Translation: AAL39931.1
RefSeqiNP_732413.1, NM_169854.2

3D structure databases

SMRiQ9VDY1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi67311, 4 interactors
IntActiQ9VDY1, 388 interactors
STRINGi7227.FBpp0083185

PTM databases

iPTMnetiQ9VDY1

Proteomic databases

PaxDbiQ9VDY1
PRIDEiQ9VDY1

Genome annotation databases

EnsemblMetazoaiFBtr0083771; FBpp0083185; FBgn0086613
GeneIDi42314
KEGGidme:Dmel_CG31212
UCSCiCG31212-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54617
FlyBaseiFBgn0086613 Ino80

Phylogenomic databases

eggNOGiKOG0388 Eukaryota
ENOG410XP0A LUCA
GeneTreeiENSGT00900000141110
HOGENOMiCLU_000315_19_0_1
InParanoidiQ9VDY1
KOiK11665
OMAiNTMAEVR
OrthoDBi188211at2759
PhylomeDBiQ9VDY1

Enzyme and pathway databases

ReactomeiR-DME-5689603 UCH proteinases
R-DME-5696394 DNA Damage Recognition in GG-NER

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
42314 1 hit in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ino80 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
42314

Protein Ontology

More...
PROi
PR:Q9VDY1

Gene expression databases

BgeeiFBgn0086613 Expressed in embryo and 25 other tissues
ExpressionAtlasiQ9VDY1 differential
GenevisibleiQ9VDY1 DM

Family and domain databases

Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR020838 DBINO
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR031047 Ino80
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PANTHERiPTHR45685:SF2 PTHR45685:SF2, 1 hit
PfamiView protein in Pfam
PF13892 DBINO, 1 hit
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51413 DBINO, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiINO80_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VDY1
Secondary accession number(s): Q8T9F9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: March 1, 2003
Last modified: June 17, 2020
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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