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UniProtKB - Q9VDV5 (Q9VDV5_DROME)
Protein
Submitted name:
FI18650p1
Gene
Dmel\CG6231
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
Enzyme and pathway databases
Reactomei | R-DME-112311, Neurotransmitter clearance R-DME-181430, Norepinephrine Neurotransmitter Release Cycle R-DME-197264, Nicotinamide salvaging R-DME-200425, Carnitine metabolism R-DME-2161517, Abacavir transmembrane transport R-DME-442660, Na+/Cl- dependent neurotransmitter transporters R-DME-549127, Organic cation transport R-DME-561048, Organic anion transport |
Names & Taxonomyi
Protein namesi | Submitted name: FI18650p1ImportedSubmitted name: Uncharacterized protein, isoform AImportedSubmitted name: Uncharacterized protein, isoform BImportedSubmitted name: Uncharacterized protein, isoform CImportedSubmitted name: Uncharacterized protein, isoform DImportedSubmitted name: Uncharacterized protein, isoform EImportedSubmitted name: Uncharacterized protein, isoform FImported |
Gene namesi | Name:Dmel\CG6231Imported Synonyms:CG6231-RDImported ORF Names:CG6231Imported, Dmel_CG6231Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0038720, CG6231 |
VEuPathDBi | VectorBase:FBgn0038720 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 16 – 36 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 122 – 141 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 148 – 167 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 179 – 200 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 207 – 228 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 234 – 255 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 328 – 345 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 357 – 377 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 389 – 408 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 414 – 432 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 453 – 472 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 478 – 498 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | FBgn0038720, Expressed in Malpighian tubule and 33 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9VDV5, 3 interactors |
STRINGi | 7227.FBpp0083217 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 23 – 503 | MFSInterPro annotationAdd BLAST | 481 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 557 – 585 | DisorderedSequence analysisAdd BLAST | 29 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 568 – 585 | Basic and acidic residuesSequence analysisAdd BLAST | 18 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG0255, Eukaryota |
GeneTreei | ENSGT00940000165745 |
HOGENOMi | CLU_001265_33_4_1 |
OMAi | KWIYNYD |
OrthoDBi | 435631at2759 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VDV5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDFDQILAKC GDFNRYQFMI LALFGFINII VSMHYFTQTV ISFVPDHWCY
60 70 80 90 100
HDKLVNMTYK EIGEIYAQFE NPSCTRLDDI NGHNVTVSSK ACEKWIYNYD
110 120 130 140 150
FGYRSMNTEL NWVCDSAYKA RIGQSLFFIG SVVGTLFYGL LSDKIGRVPA
160 170 180 190 200
LILSNFCGFA GDFSTIFTKS VATFTLCRFI SGLAADTNFY LMYIIVLEYI
210 220 230 240 250
RPSMRTLGLN MAVGLFYCLG LVFTPWLAVL VGHWQIYLAC TSLPILLVVL
260 270 280 290 300
YYFVVQESAQ WLVTRNDIDG AIVRLKRVAK FNGCRVSQAD FDEFRRHCQM
310 320 330 340 350
THEMLGGDDK KQATLLDMFR TPRMRKNTLI LFFKSMVITL CYDAVSRNVE
360 370 380 390 400
GMGISPFIMF SLSALAVLPS SVLLVLLQDR IGRKGMASGS LLVGGLFTAA
410 420 430 440 450
AGIAIAYQQH NHNAILLACL TIAARFGVAI SYESGSQYAT ELIPTCVRGQ
460 470 480 490 500
GVAAVHVAGF AASFLAPYIL WLGTFFKAAP SIILGVLFFA GSFVCLLLPE
510 520 530 540 550
TLNRSLPTTI EEGEVFGKGE RMFDFPCLHN KHDDEESESE LEKYKRKHSL
560 570 580
IDAKQMQMES CSNGKRKQSL IDADHEEQAL KDANH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF55684.2 AE014297 Genomic DNA Translation: AAN13801.1 AE014297 Genomic DNA Translation: AAN13802.1 AE014297 Genomic DNA Translation: AAN13803.1 BT133172 mRNA Translation: AEZ68800.1 AE014297 Genomic DNA Translation: AGB96114.1 AE014297 Genomic DNA Translation: AGB96115.1 |
RefSeqi | NP_001262734.1, NM_001275805.1 NP_001262735.1, NM_001275806.1 NP_650819.1, NM_142562.3 NP_732435.1, NM_169864.2 NP_732436.1, NM_169865.2 NP_732437.1, NM_169866.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0083807; FBpp0083217; FBgn0038720 FBtr0083808; FBpp0083218; FBgn0038720 FBtr0083809; FBpp0083219; FBgn0038720 FBtr0083810; FBpp0083220; FBgn0038720 FBtr0334923; FBpp0306943; FBgn0038720 FBtr0334924; FBpp0306944; FBgn0038720 |
GeneIDi | 42339 |
KEGGi | dme:Dmel_CG6231 |
UCSCi | CG6231-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF55684.2 AE014297 Genomic DNA Translation: AAN13801.1 AE014297 Genomic DNA Translation: AAN13802.1 AE014297 Genomic DNA Translation: AAN13803.1 BT133172 mRNA Translation: AEZ68800.1 AE014297 Genomic DNA Translation: AGB96114.1 AE014297 Genomic DNA Translation: AGB96115.1 |
RefSeqi | NP_001262734.1, NM_001275805.1 NP_001262735.1, NM_001275806.1 NP_650819.1, NM_142562.3 NP_732435.1, NM_169864.2 NP_732436.1, NM_169865.2 NP_732437.1, NM_169866.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9VDV5, 3 interactors |
STRINGi | 7227.FBpp0083217 |
Protocols and materials databases
DNASUi | 42339 |
Genome annotation databases
EnsemblMetazoai | FBtr0083807; FBpp0083217; FBgn0038720 FBtr0083808; FBpp0083218; FBgn0038720 FBtr0083809; FBpp0083219; FBgn0038720 FBtr0083810; FBpp0083220; FBgn0038720 FBtr0334923; FBpp0306943; FBgn0038720 FBtr0334924; FBpp0306944; FBgn0038720 |
GeneIDi | 42339 |
KEGGi | dme:Dmel_CG6231 |
UCSCi | CG6231-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0038720, CG6231 |
VEuPathDBi | VectorBase:FBgn0038720 |
Phylogenomic databases
eggNOGi | KOG0255, Eukaryota |
GeneTreei | ENSGT00940000165745 |
HOGENOMi | CLU_001265_33_4_1 |
OMAi | KWIYNYD |
OrthoDBi | 435631at2759 |
Enzyme and pathway databases
Reactomei | R-DME-112311, Neurotransmitter clearance R-DME-181430, Norepinephrine Neurotransmitter Release Cycle R-DME-197264, Nicotinamide salvaging R-DME-200425, Carnitine metabolism R-DME-2161517, Abacavir transmembrane transport R-DME-442660, Na+/Cl- dependent neurotransmitter transporters R-DME-549127, Organic cation transport R-DME-561048, Organic anion transport |
Miscellaneous databases
BioGRID-ORCSi | 42339, 0 hits in 1 CRISPR screen |
GenomeRNAii | 42339 |
Gene expression databases
Bgeei | FBgn0038720, Expressed in Malpighian tubule and 33 other tissues |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VDV5_DROME | |
Accessioni | Q9VDV5Primary (citable) accession number: Q9VDV5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | October 1, 2002 | |
Last modified: | May 25, 2022 | |
This is version 175 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |