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Entry version 148 (29 Sep 2021)
Sequence version 2 (01 Mar 2003)
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Protein

Protein CREBRF homolog

Gene

REPTOR

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts as the transcriptional activator. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphorylating REPTOR and mediates its cytoplasmic retention by forming a docking site for 14-3-3 proteins. Upon TORC1 inhibition resulting from nutrient stress, REPTOR is recruited into the nucleus where it interacts with REPTOR-BP and together they maintain organismal metabolism by activating the expression of target stress response genes including those involved in glycogenesis and triglyceride biosynthesis. The complex also appears to negatively regulate some aspects of TORC1-dependent larval growth.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein CREBRF homologCurated
Alternative name(s):
Protein Repressed by Tor1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:REPTOR1 PublicationImported
ORF Names:CG13624Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0039209, REPTOR

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
VectorBase:FBgn0039209

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Sensitive to nutrient stress. Larvae display no obvious phenotype under normal feeding conditions; larval growth and development is normal, and there is no effect on triglyceride and glycogen levels. However when mutants pupate and become adults they display reduced triglyceride and glycogen stores leading to adults dying within 18 hours of starvation whereas controls survive 2.5 days without food. Larvae are also sensitive to nutrient stress displaying 50% lethality when fed a low nutrient diet. Double knockouts of REPTOR with a hypomorphic Tor, rescue the Tor-mediated increase in triglyceride levels and partially rescue the larval growth defect.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi527S → A: Nuclear localization and induces transcriptional activity; when associated with A-530. 1 Publication1
Mutagenesisi530S → A: Nuclear localization and induces transcriptional activity; when associated with A-527. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002993081 – 755Protein CREBRF homologAdd BLAST755

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei442Phosphoserine1 Publication1
Modified residuei443Phosphoserine1 Publication1
Modified residuei505Phosphoserine1 Publication1
Modified residuei527Phosphoserine; by TORC11 Publication1
Modified residuei530Phosphoserine; by TORC11 Publication1
Modified residuei589Phosphothreonine1 Publication1
Modified residuei595Phosphoserine1 Publication1
Modified residuei596Phosphoserine1 Publication1
Modified residuei665Phosphothreonine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation by the TORC1 kinase complex at Ser-527 and Ser-530 abolishes nuclear localization. Upon TORC1 inhibition, dephosphorylated in a mts/PP2a-dependent manner leading to nuclear localization.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VC61

PRoteomics IDEntifications database

More...
PRIDEi
Q9VC61

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q9VC61

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0039209, Expressed in digestive system element and 59 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9VC61, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q9VC61, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via C-terminus) with REPTOR-BP (via C-terminus).

Interacts with the TORC1 complex component raptor.

Interacts (when phosphorylated) with 14-3-3zeta, this interaction may assist its cytoplasmic retention.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
67856, 20 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VC61, 4 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0110092

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VC61

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini697 – 755bZIPAdd BLAST59

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni51 – 80DisorderedSequence analysisAdd BLAST30
Regioni99 – 154DisorderedSequence analysisAdd BLAST56
Regioni368 – 422DisorderedSequence analysisAdd BLAST55
Regioni438 – 483DisorderedSequence analysisAdd BLAST46
Regioni538 – 596DisorderedSequence analysisAdd BLAST59
Regioni699 – 708Basic motifPROSITE-ProRule annotation10
Regioni709 – 716Leucine-zipperPROSITE-ProRule annotation8

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi99 – 119Polar residuesSequence analysisAdd BLAST21
Compositional biasi126 – 154Polar residuesSequence analysisAdd BLAST29
Compositional biasi368 – 406Polar residuesSequence analysisAdd BLAST39
Compositional biasi445 – 483Polar residuesSequence analysisAdd BLAST39
Compositional biasi552 – 566Acidic residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the bZIP family. CREBRF subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502QTAK, Eukaryota

Ensembl GeneTree

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GeneTreei
ENSGT00390000007125

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9VC61

Identification of Orthologs from Complete Genome Data

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OMAi
YFAPDMS

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR004827, bZIP
IPR039165, CREBRF

The PANTHER Classification System

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PANTHERi
PTHR21552, PTHR21552, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS00036, BZIP_BASIC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform AImported (identifier: Q9VC61-1) [UniParc]FASTAAdd to basket
Also known as: BImported, CImported, DImported, GImported

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTENQLYPMS SEFFDTGSNS SSNTLKYDLY SLGSTVVGAA LPTLTINTGY
60 70 80 90 100
GSSSSNNNNT NNNNNNSSSH SSSSNCSTST TNTCNVMLST TAITIPRSSN
110 120 130 140 150
HNQIHHHPYQ QSDLQTPRHH PSPLHTLPSM THQQNQLQQQ QQQQHHNQQQ
160 170 180 190 200
QLQQSHLALG ELSDFGLDAL DAASLSPTLL QDVSLSAVSP LSTTLYNGNT
210 220 230 240 250
SGAGSSNGIG SGSGGYFTPD MSHSLSLNVV SEQVLLQEAT TPNELLYEMT
260 270 280 290 300
PNSNAMWSDI SSAIIHTKHE PFSLDDDYIF PNDKAEIQAA DLSDLNGGDF
310 320 330 340 350
LDVIGNIEDF LPQTAVTQSV NFLLSPQAQG QDALVAPPME LLQQQQQNHQ
360 370 380 390 400
QLQVGSLPQL QTLLTLSQQQ QSNSSSTSPY EIYHSTPQKP QQQQLSASFS
410 420 430 440 450
PGSQASQSPL TPPPPPHANR PQYQMVKSRN MQELIKKGFP MSSPPERSIL
460 470 480 490 500
SQSAALSPGG SSGFGSSASG NSTTTSNQTS GSAVRKSFGY QSAVENSQLS
510 520 530 540 550
RLSSSAPTHL GLEHIWMRRE PRQHLLSTGS LAEAESFSSL STGSVLSPDG
560 570 580 590 600
IDFSQDDEDD NSSENSDNYD DCSSDNGLSE DEDETRTSTP NHLSSSKGKE
610 620 630 640 650
RFFWQYNVQA KGPKGKRLVF QSKLEDPHVL NEVTDPVFSP TCSVRGIKVY
660 670 680 690 700
KHSGKARKGD GNDLTPNARK LHNIGKELDK LSRTINDMTP VSELPFNVRP
710 720 730 740 750
KSRKEKNKLA SRACRLKKKA QHEANKIKLF GLEIEHSEFN VKAVEISYNP

SIFVL
Length:755
Mass (Da):82,263
Last modified:March 1, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD851D42235FF10E5
GO
Isoform EImported (identifier: Q9VC61-2) [UniParc]FASTAAdd to basket
Also known as: FImported

The sequence of this isoform differs from the canonical sequence as follows:
     737-755: SEFNVKAVEISYNPSIFVL → KRLMNGIAEL...GGLEELRKSS

Show »
Length:814
Mass (Da):88,578
Checksum:iD14D317BED16C096
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4LHL0A0A0B4LHL0_DROME
Repressed by TOR, isoform G
REPTOR anon-WO0153538.65, DM23, DM24, Dmel\CG13624, reptor
755Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_027604737 – 755SEFNV…SIFVL → KRLMNGIAELKQALVVKHRT KNLGESTEEVDQQIARIYAT ASSGIRIAGGSTDFVNKVLE NMRGGMPNGGLEELRKSS in isoform E. CuratedAdd BLAST19

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56314.2
AE014297 Genomic DNA Translation: AAN14001.1
AE014297 Genomic DNA Translation: AAN14002.1
AE014297 Genomic DNA Translation: AAN14003.1
AE014297 Genomic DNA Translation: ABI31203.1
AE014297 Genomic DNA Translation: ABI31204.1
AY069850 mRNA Translation: AAL39995.1

NCBI Reference Sequences

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RefSeqi
NP_001036752.1, NM_001043287.2 [Q9VC61-2]
NP_001036753.1, NM_001043288.2 [Q9VC61-2]
NP_001287505.1, NM_001300576.1 [Q9VC61-1]
NP_651271.1, NM_143014.3 [Q9VC61-1]
NP_733012.1, NM_170150.2 [Q9VC61-1]
NP_733013.1, NM_170151.2 [Q9VC61-1]
NP_733014.1, NM_170152.2 [Q9VC61-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0084672; FBpp0084052; FBgn0039209 [Q9VC61-1]
FBtr0084673; FBpp0084053; FBgn0039209 [Q9VC61-1]
FBtr0084674; FBpp0084054; FBgn0039209 [Q9VC61-1]
FBtr0084675; FBpp0084055; FBgn0039209 [Q9VC61-1]
FBtr0110795; FBpp0110092; FBgn0039209 [Q9VC61-2]
FBtr0110796; FBpp0110093; FBgn0039209 [Q9VC61-2]
FBtr0345204; FBpp0311399; FBgn0039209 [Q9VC61-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
42930

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG13624

UCSC genome browser

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UCSCi
CG13624-RA, d. melanogaster [Q9VC61-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56314.2
AE014297 Genomic DNA Translation: AAN14001.1
AE014297 Genomic DNA Translation: AAN14002.1
AE014297 Genomic DNA Translation: AAN14003.1
AE014297 Genomic DNA Translation: ABI31203.1
AE014297 Genomic DNA Translation: ABI31204.1
AY069850 mRNA Translation: AAL39995.1
RefSeqiNP_001036752.1, NM_001043287.2 [Q9VC61-2]
NP_001036753.1, NM_001043288.2 [Q9VC61-2]
NP_001287505.1, NM_001300576.1 [Q9VC61-1]
NP_651271.1, NM_143014.3 [Q9VC61-1]
NP_733012.1, NM_170150.2 [Q9VC61-1]
NP_733013.1, NM_170151.2 [Q9VC61-1]
NP_733014.1, NM_170152.2 [Q9VC61-1]

3D structure databases

SMRiQ9VC61
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi67856, 20 interactors
IntActiQ9VC61, 4 interactors
STRINGi7227.FBpp0110092

PTM databases

iPTMnetiQ9VC61

Proteomic databases

PaxDbiQ9VC61
PRIDEiQ9VC61

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
42930

Genome annotation databases

EnsemblMetazoaiFBtr0084672; FBpp0084052; FBgn0039209 [Q9VC61-1]
FBtr0084673; FBpp0084053; FBgn0039209 [Q9VC61-1]
FBtr0084674; FBpp0084054; FBgn0039209 [Q9VC61-1]
FBtr0084675; FBpp0084055; FBgn0039209 [Q9VC61-1]
FBtr0110795; FBpp0110092; FBgn0039209 [Q9VC61-2]
FBtr0110796; FBpp0110093; FBgn0039209 [Q9VC61-2]
FBtr0345204; FBpp0311399; FBgn0039209 [Q9VC61-1]
GeneIDi42930
KEGGidme:Dmel_CG13624
UCSCiCG13624-RA, d. melanogaster [Q9VC61-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
42930
FlyBaseiFBgn0039209, REPTOR
VEuPathDBiVectorBase:FBgn0039209

Phylogenomic databases

eggNOGiENOG502QTAK, Eukaryota
GeneTreeiENSGT00390000007125
InParanoidiQ9VC61
OMAiYFAPDMS

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
42930, 0 hits in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
REPTOR, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
42930

Protein Ontology

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PROi
PR:Q9VC61

Gene expression databases

BgeeiFBgn0039209, Expressed in digestive system element and 59 other tissues
ExpressionAtlasiQ9VC61, baseline and differential
GenevisibleiQ9VC61, DM

Family and domain databases

InterProiView protein in InterPro
IPR004827, bZIP
IPR039165, CREBRF
PANTHERiPTHR21552, PTHR21552, 1 hit
PROSITEiView protein in PROSITE
PS00036, BZIP_BASIC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCRERF_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VC61
Secondary accession number(s): Q0KI17, Q8T9A9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2003
Last modified: September 29, 2021
This is version 148 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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