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Entry version 188 (29 Sep 2021)
Sequence version 1 (01 May 2000)
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Protein

Metalloendopeptidase

Gene

tok

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi614Zinc; catalyticUniRule annotation1
Metal bindingi614Zinc; via tele nitrogen; catalyticPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei615UniRule annotation1
Metal bindingi618Zinc; catalyticUniRule annotation1
Metal bindingi618Zinc; via tele nitrogen; catalyticPROSITE-ProRule annotation1
Metal bindingi624Zinc; catalyticUniRule annotation1
Metal bindingi624Zinc; via tele nitrogen; catalyticPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, MetalloproteasePROSITE-ProRule annotationARBA annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotationARBA annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-1650814, Collagen biosynthesis and modifying enzymes
R-DME-2243919, Crosslinking of collagen fibrils

Protein family/group databases

MEROPS protease database

More...
MEROPSi
M12.011

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MetalloendopeptidaseUniRule annotation (EC:3.4.24.-UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tokImported
Synonyms:CT21251Imported, Dmel\CG6863Imported, tldr-1Imported, tldr1Imported, TLRImported, TlrImported, tlrImported, Tlr-1Imported, tlr-1Imported, tlr1Imported, TOKImported, TokImported
ORF Names:CG6863Imported, Dmel_CG6863Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0004885, tok

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:FBgn0004885

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 33UniRule annotationAdd BLAST33
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501502016234 – 1464MetalloendopeptidaseUniRule annotationAdd BLAST1431

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi584 ↔ 606PROSITE-ProRule annotation
Disulfide bondi586 ↔ 587PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9VC47

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0004885, Expressed in wing disc (Drosophila) and 42 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VC47, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0084068

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VC47

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini519 – 721Peptidase M12AInterPro annotationAdd BLAST203
Domaini723 – 839CUBInterPro annotationAdd BLAST117
Domaini840 – 954CUBInterPro annotationAdd BLAST115
Domaini954 – 994EGF-likeInterPro annotationAdd BLAST41
Domaini997 – 1114CUBInterPro annotationAdd BLAST118
Domaini1114 – 1154EGF-likeInterPro annotationAdd BLAST41
Domaini1158 – 1270CUBInterPro annotationAdd BLAST113
Domaini1271 – 1391CUBInterPro annotationAdd BLAST121

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni40 – 99DisorderedSequence analysisAdd BLAST60
Regioni179 – 210DisorderedSequence analysisAdd BLAST32
Regioni248 – 349DisorderedSequence analysisAdd BLAST102
Regioni362 – 382DisorderedSequence analysisAdd BLAST21
Regioni396 – 419DisorderedSequence analysisAdd BLAST24
Regioni434 – 497DisorderedSequence analysisAdd BLAST64

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi255 – 295Polar residuesSequence analysisAdd BLAST41
Compositional biasi327 – 349Basic and acidic residuesSequence analysisAdd BLAST23
Compositional biasi362 – 377Polar residuesSequence analysisAdd BLAST16
Compositional biasi396 – 410Basic residuesSequence analysisAdd BLAST15
Compositional biasi441 – 469Basic residuesSequence analysisAdd BLAST29
Compositional biasi470 – 497Polar residuesSequence analysisAdd BLAST28

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationARBA annotation, SignalUniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3714, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155299

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005140_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
VDPFENS

Database of Orthologous Groups

More...
OrthoDBi
170905at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VC47

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00041, CUB, 5 hits
cd04281, ZnMc_BMP1_TLD, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.290, 5 hits
3.40.390.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015446, BMP_1/tolloid-like
IPR000859, CUB_dom
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR024079, MetalloPept_cat_dom_sf
IPR001506, Peptidase_M12A
IPR006026, Peptidase_Metallo
IPR035914, Sperma_CUB_dom_sf
IPR034036, ZnMP_TLD/BMP1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01400, Astacin, 1 hit
PF00431, CUB, 5 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF001199, BMP_1/tolloid-like, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00480, ASTACIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00042, CUB, 5 hits
SM00181, EGF, 2 hits
SM00179, EGF_CA, 2 hits
SM00235, ZnMc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49854, SSF49854, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51864, ASTACIN, 1 hit
PS00010, ASX_HYDROXYL, 2 hits
PS01180, CUB, 5 hits
PS01186, EGF_2, 2 hits
PS50026, EGF_3, 2 hits
PS01187, EGF_CA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VC47-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRRRGTPLG VSWTNCVLLL ATGLLVVLIS VHAKNPRPHR GLPAPAPAPV
60 70 80 90 100
PASVDQVATE NAHRREPTVD GSVLQRLSGS DRAVDEDEDV DEDEDEGLKH
110 120 130 140 150
QHLEHRQQFD AYLGTIRRLR RPYRSKYTIE QLMRLHVTPK VSGDIDMDPC
160 170 180 190 200
KAGGFMGDIA LPEGDSGPVV AHTPIDDEEQ ERQEVEQLLA DSPSPVHDPP
210 220 230 240 250
SVSGAANSGP TKFNATFQLD LEKLKQEVYH EGLQVEEEGL TDIIRKKTKL
260 270 280 290 300
PSSGPVNLKA GQSQSQSQSA NEPVKPGSES PSDYAQASSY KNEVLPPSEQ
310 320 330 340 350
RIHTDKPARL TLAEIGPKFS NKTQSLHRNV DTRKIQSDNK DIEDDSGNNF
360 370 380 390 400
VAERRPSQIV PTSLPEQRST PAHVYSNAGG NGMQLDDEVD FLHSRGVVRR
410 420 430 440 450
RHRRGPKQRR SNQHLEHEVK LQRLREELSR PVIEAHHHQS HHQKQAQHRQ
460 470 480 490 500
HHQSHHRKKH RRQQQHHRRR GQSTTQYVNH SPPGFNQSQQ AQQQSVPEMD
510 520 530 540 550
LLKAETSKDE EPLRHRVARA VTAKKERIWD YGVIPYEIDG NFSGIHKALF
560 570 580 590 600
KLAMRHWENS TCIKFVERDP EIHPNYIVFT VRSCGCCSFV GKRGNGPQAI
610 620 630 640 650
SIGRNCDKFG IVVHELGHVV GFWHEHTRPD REKHVVIEHN NIMKGQDYNF
660 670 680 690 700
NMLSPDEVDS LGMAYDYDSI MHYARNTFSK GTYLDTILPI EMKGRKRPEI
710 720 730 740 750
GQRLRLSQGD IAQANLLYKC PKCGRTFQES SGIFASPSHY TAGALSNETE
760 770 780 790 800
HCEWRITATY GERVELKLEN MNIFKSNNCE TDYLEIRDGY FEKSPLIGRF
810 820 830 840 850
CGKVDKEVIR TESSRMLLTY VNTHRIEGFR GFKAEFDVVC GGELSVDDAV
860 870 880 890 900
GRLESPNYPL DYLPNKECVW KITVPESYQV ALKFQSFEVE NHDSCVYDYV
910 920 930 940 950
EVRDGPGQDA PLIGVFCGYK PPPNMKSSGN SMYVKFVSDT SVQKAGFSAV
960 970 980 990 1000
FMKEVDECET QNHGCEHECI NTLGGYECSC RIGFELHSDK KHCEDACGGV
1010 1020 1030 1040 1050
IEYPNGTITS PSFPEMYPLL KECIWEIVAP PKHRISLNFT HFDLEGTAHQ
1060 1070 1080 1090 1100
QSDCGYDSVT VYSKLGENRL KRIGTFCGSS IPPTATSESN ALRLEFHSDK
1110 1120 1130 1140 1150
SIQRSGFAAV FFTDIDECAV NNGGCQHECR NTIGSYICMC HNGYSMHENG
1160 1170 1180 1190 1200
HDCKEGECKY EISAPFGTIF SPNYPDSYPP NADCVWHFIT TPGHRIKLIF
1210 1220 1230 1240 1250
NEFDVESHQE CTYDNVAVYD GESESSSVLG RFCGDKIPFP ISSTSNQMYM
1260 1270 1280 1290 1300
VLKTDKNKQK NGFTASHSTA CGGYLRATSQ VQQFYSHARF GNQDYDDGMD
1310 1320 1330 1340 1350
CEWTIAAPDN SYVQLIFLTF DIESSENCTF DYVQVFSDID DVYGQYGPMY
1360 1370 1380 1390 1400
GQYCGNVLPQ DINSMTHSLL VRFKTDGSVP MKGFSASYVA VPNSGEYDHS
1410 1420 1430 1440 1450
DEDVENSYSS EMVTPFPGSL KSIYIEDTQE ETDEYSDFSG NQLVFNGQYR
1460
GRYSLPKRYY SGKA
Length:1,464
Mass (Da):165,219
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i029BE1560DBE9056
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56328.1
AY051585 mRNA Translation: AAK93009.1
AE014297 Genomic DNA Translation: AAN14017.1
AE014297 Genomic DNA Translation: AHN57509.1

NCBI Reference Sequences

More...
RefSeqi
NP_001287510.1, NM_001300581.1
NP_476879.1, NM_057531.4
NP_733035.1, NM_170168.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0084689; FBpp0084068; FBgn0004885
FBtr0084690; FBpp0084069; FBgn0004885
FBtr0339252; FBpp0308359; FBgn0004885

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42944

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG6863

UCSC genome browser

More...
UCSCi
CG6863-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56328.1
AY051585 mRNA Translation: AAK93009.1
AE014297 Genomic DNA Translation: AAN14017.1
AE014297 Genomic DNA Translation: AHN57509.1
RefSeqiNP_001287510.1, NM_001300581.1
NP_476879.1, NM_057531.4
NP_733035.1, NM_170168.2

3D structure databases

SMRiQ9VC47
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0084068

Protein family/group databases

MEROPSiM12.011

Proteomic databases

PRIDEiQ9VC47

Genome annotation databases

EnsemblMetazoaiFBtr0084689; FBpp0084068; FBgn0004885
FBtr0084690; FBpp0084069; FBgn0004885
FBtr0339252; FBpp0308359; FBgn0004885
GeneIDi42944
KEGGidme:Dmel_CG6863
UCSCiCG6863-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
42944
FlyBaseiFBgn0004885, tok
VEuPathDBiVectorBase:FBgn0004885

Phylogenomic databases

eggNOGiKOG3714, Eukaryota
GeneTreeiENSGT00940000155299
HOGENOMiCLU_005140_0_0_1
OMAiVDPFENS
OrthoDBi170905at2759
PhylomeDBiQ9VC47

Enzyme and pathway databases

ReactomeiR-DME-1650814, Collagen biosynthesis and modifying enzymes
R-DME-2243919, Crosslinking of collagen fibrils

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
42944, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
42944

Gene expression databases

BgeeiFBgn0004885, Expressed in wing disc (Drosophila) and 42 other tissues
ExpressionAtlasiQ9VC47, baseline and differential

Family and domain databases

CDDicd00041, CUB, 5 hits
cd04281, ZnMc_BMP1_TLD, 1 hit
Gene3Di2.60.120.290, 5 hits
3.40.390.10, 1 hit
InterProiView protein in InterPro
IPR015446, BMP_1/tolloid-like
IPR000859, CUB_dom
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR024079, MetalloPept_cat_dom_sf
IPR001506, Peptidase_M12A
IPR006026, Peptidase_Metallo
IPR035914, Sperma_CUB_dom_sf
IPR034036, ZnMP_TLD/BMP1
PfamiView protein in Pfam
PF01400, Astacin, 1 hit
PF00431, CUB, 5 hits
PIRSFiPIRSF001199, BMP_1/tolloid-like, 1 hit
PRINTSiPR00480, ASTACIN
SMARTiView protein in SMART
SM00042, CUB, 5 hits
SM00181, EGF, 2 hits
SM00179, EGF_CA, 2 hits
SM00235, ZnMc, 1 hit
SUPFAMiSSF49854, SSF49854, 5 hits
PROSITEiView protein in PROSITE
PS51864, ASTACIN, 1 hit
PS00010, ASX_HYDROXYL, 2 hits
PS01180, CUB, 5 hits
PS01186, EGF_2, 2 hits
PS50026, EGF_3, 2 hits
PS01187, EGF_CA, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VC47_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VC47
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 29, 2021
This is version 188 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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