UniProtKB - Q9VBZ9 (Q9VBZ9_DROME)
Protein
Submitted name:
Beta-4-galactosyltransferase 7
Gene
beta4GalT7
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
: protein glycosylation Pathwayi
This protein is involved in the pathway protein glycosylation, which is part of Protein modification.ARBA annotationView all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 121 | UDPCombined sources | 1 | |
Metal bindingi | 147 | ManganeseCombined sources | 1 | |
Binding sitei | 177 | UDPCombined sources | 1 | |
Binding sitei | 207 | UDPCombined sources | 1 | |
Metal bindingi | 241 | Manganese; via tele nitrogenCombined sources | 1 | |
Metal bindingi | 243 | Manganese; via pros nitrogenCombined sources | 1 | |
Binding sitei | 250 | UDPCombined sources | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 82 – 86 | UDPCombined sources | 5 | |
Nucleotide bindingi | 146 – 147 | UDPCombined sources | 2 | |
Nucleotide bindingi | 241 – 243 | UDPCombined sources | 3 |
GO - Molecular functioni
- metal ion binding Source: FlyBase
- nucleotide binding Source: UniProtKB-KW
- xylosylprotein 4-beta-galactosyltransferase activity Source: FlyBase
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
- N-glycan processing Source: FlyBase
- protein glycosylation Source: UniProtKB-UniPathway
- proteoglycan biosynthetic process Source: FlyBase
Keywordsi
Molecular function | GlycosyltransferaseImportedARBA annotation, Transferase |
Ligand | ManganeseCombined sources, Metal-bindingCombined sources, Nucleotide-bindingCombined sources |
Enzyme and pathway databases
Reactomei | R-DME-1971475, A tetrasaccharide linker sequence is required for GAG synthesis |
UniPathwayi | UPA00378 |
Protein family/group databases
CAZyi | GT7, Glycosyltransferase Family 7 |
Names & Taxonomyi
Protein namesi | Submitted name: Beta-4-galactosyltransferase 7Imported (EC:2.4.1.133Imported)Submitted name: FI08434pImported |
Gene namesi | Name:beta4GalT7Imported Synonyms:beta-4GalT7Imported, beta4Gal-T7Imported, beta4GalT7-RAImported, beta4GalTIImported, betaGalT7Imported, Dbeta4GalT7Imported, dbeta4GalT7Imported, dbeta4GalTIImported, dGAGbeta4GalTIImported, Dmel\CG11780Imported, GalTImported, GalTIImported ORF Names:CG11780Imported, Dmel_CG11780Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0039258, beta4GalT7 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type II membrane protein ARBA annotation
Golgi apparatus
- Golgi apparatus Source: FlyBase
Other locations
- integral component of membrane Source: FlyBase
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 7 – 30 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembranePTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 255 ↔ 310 | Combined sources | ||
Disulfide bondi | 300 ↔ 308 | Combined sources |
Keywords - PTMi
GlycoproteinARBA annotationExpressioni
Gene expression databases
Bgeei | FBgn0039258, Expressed in secondary oocyte and 36 other tissues |
Structurei
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 71 – 158 | Glyco_transf_7NInterPro annotationAdd BLAST | 88 | |
Domaini | 165 – 238 | Glyco_transf_7CInterPro annotationAdd BLAST | 74 |
Sequence similaritiesi
Belongs to the glycosyltransferase 7 family.ARBA annotation
Keywords - Domaini
Signal-anchorARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3917, Eukaryota |
GeneTreei | ENSGT00940000157712 |
HOGENOMi | CLU_044391_5_0_1 |
OMAi | FSHIHNR |
OrthoDBi | 1201618at2759 |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR003859, Galactosyl_T IPR027791, Galactosyl_T_C IPR027995, Galactosyl_T_N IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR19300, PTHR19300, 1 hit |
Pfami | View protein in Pfam PF02709, Glyco_transf_7C, 1 hit PF13733, Glyco_transf_7N, 1 hit |
PRINTSi | PR02050, B14GALTRFASE |
SUPFAMi | SSF53448, SSF53448, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VBZ9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVNISTINWV FVCGLSFCLG GIAVLSLMPL GSDCVCPLSN PLAKLAGGGE
60 70 80 90 100
GVSVIKKEPA DEKQPQPHDH GASVHKMALL VPFRDRFEEL LQFVPHMTAF
110 120 130 140 150
LKRQGVAHHI FVLNQVDRFR FNRASLINVG FQFASDVYDY IAMHDVDLLP
160 170 180 190 200
LNDNLLYEYP SSLGPLHIAG PKLHPKYHYD NFVGGILLVR REHFKQMNGM
210 220 230 240 250
SNQYWGWGLE DDEFFVRIRD AGLQVTRPQN IKTGTNDTFS HIHNRYHRKR
260 270 280 290 300
DTQKCFNQKE MTRKRDHKTG LDNVKYKILK VHEMLIDQVP VTILNILLDC
310 320
DVNKTPWCDC SGTAAAASAV QT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF56377.1 BT044519 mRNA Translation: ACH95293.1 |
RefSeqi | NP_651319.2, NM_143062.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0084755; FBpp0084130; FBgn0039258 |
GeneIDi | 42991 |
KEGGi | dme:Dmel_CG11780 |
UCSCi | CG11780-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF56377.1 BT044519 mRNA Translation: ACH95293.1 |
RefSeqi | NP_651319.2, NM_143062.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3LW6 | X-ray | 1.81 | A | 71-311 | [»] | |
4LW3 | X-ray | 2.00 | A | 71-311 | [»] | |
4LW6 | X-ray | 2.40 | A | 71-311 | [»] | |
4M4K | X-ray | 2.20 | A | 71-311 | [»] | |
ModBasei | Search... | |||||
SWISS-MODEL-Workspacei | Submit a new modelling project... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 7227.FBpp0084130 |
Protein family/group databases
CAZyi | GT7, Glycosyltransferase Family 7 |
Genome annotation databases
EnsemblMetazoai | FBtr0084755; FBpp0084130; FBgn0039258 |
GeneIDi | 42991 |
KEGGi | dme:Dmel_CG11780 |
UCSCi | CG11780-RA, d. melanogaster |
Organism-specific databases
CTDi | 42991 |
FlyBasei | FBgn0039258, beta4GalT7 |
Phylogenomic databases
eggNOGi | KOG3917, Eukaryota |
GeneTreei | ENSGT00940000157712 |
HOGENOMi | CLU_044391_5_0_1 |
OMAi | FSHIHNR |
OrthoDBi | 1201618at2759 |
Enzyme and pathway databases
UniPathwayi | UPA00378 |
Reactomei | R-DME-1971475, A tetrasaccharide linker sequence is required for GAG synthesis |
Miscellaneous databases
BioGRID-ORCSi | 42991, 0 hits in 1 CRISPR screen |
GenomeRNAii | 42991 |
Gene expression databases
Bgeei | FBgn0039258, Expressed in secondary oocyte and 36 other tissues |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR003859, Galactosyl_T IPR027791, Galactosyl_T_C IPR027995, Galactosyl_T_N IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR19300, PTHR19300, 1 hit |
Pfami | View protein in Pfam PF02709, Glyco_transf_7C, 1 hit PF13733, Glyco_transf_7N, 1 hit |
PRINTSi | PR02050, B14GALTRFASE |
SUPFAMi | SSF53448, SSF53448, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VBZ9_DROME | |
Accessioni | Q9VBZ9Primary (citable) accession number: Q9VBZ9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 10, 2021 | |
This is version 158 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |