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Entry version 143 (12 Aug 2020)
Sequence version 5 (01 Apr 2015)
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Protein

Protein unc-13 homolog 4B

Gene

stac

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential for tracheal development in embryos. Functions with the GTPase Rab39 and downstream of dnd, to regulate lumen fusion between previously separate tracheal branches (anastomosis). Essential component of secretory lysosome-related organelles (SLs) that are present in the tracheal fusion tip cells (FCs). Mediates intracellular fusion of the extending tracheal stalk cell lumen in the FCs by recruiting the SNARE complex component Syx1A to the SLs, this may then enable the SLs to interact with complementary SNAREs (such as Syb) present in the apical membrane of the FC-FC interface and the membranes of the separate tracheal stalk cells. May also function in the maturation and exocytosis of the SLs.1 Publication

Miscellaneous

'Staccato' means detached in Italian, referring to the unclosed gaps in the tracheal lumen of mutants.1 Publication

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Ca2+PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi195Calcium 1PROSITE-ProRule annotation1
Metal bindingi201Calcium 1PROSITE-ProRule annotation1
Metal bindingi252Calcium 1PROSITE-ProRule annotation1
Metal bindingi253Calcium 1; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi254Calcium 1PROSITE-ProRule annotation1
Metal bindingi1019Calcium 2PROSITE-ProRule annotation1
Metal bindingi1025Calcium 2PROSITE-ProRule annotation1
Metal bindingi1083Calcium 2PROSITE-ProRule annotation1
Metal bindingi1085Calcium 2PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processExocytosis
LigandCalcium, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-6798695, Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein unc-13 homolog 4B1 Publication
Alternative name(s):
Protein Staccato1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:stac1 PublicationImported
Synonyms:Unc-13-4B1 Publication
ORF Names:CG34349Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0266719, stac

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cytoplasm, Cytoskeleton, Endosome, Lysosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi1124 – 1153Missing in 3B20; probable loss of function. The lumen of separate tracheal branches fails to fuse during anastomosis and Syx1A does not localize to the fusion point. 1 PublicationAdd BLAST30

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004375241 – 1153Protein unc-13 homolog 4BAdd BLAST1153

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VBY8

PRoteomics IDEntifications database

More...
PRIDEi
Q9VBY8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In stage 16-17 embryos, expressed in the epidermis, tracheal system, Malpighian tubules, boundary cells of the hindgut, muscles and dorsal vessel. Expressed in large puncta in the hemocytes. Expressed in the fusion cells of the tracheal branch tips (PubMed:27323327). Detected first in early pupae and has very high levels of expression in the adult head (PubMed:9813038).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0266719, Expressed in crop (Drosophila) and 38 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VBY8, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with Cam.

1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0292144

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VBY8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini162 – 288C2 1PROSITE-ProRule annotationAdd BLAST127
Domaini637 – 755MHD1PROSITE-ProRule annotationAdd BLAST119
Domaini869 – 975MHD2PROSITE-ProRule annotationAdd BLAST107
Domaini990 – 1114C2 2PROSITE-ProRule annotationAdd BLAST125

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the unc-13 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1328, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000110939

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003295_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VBY8

Identification of Orthologs from Complete Genome Data

More...
OMAi
FYQIKVF

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VBY8

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR014770, Munc13_1
IPR014772, Munc13_dom-2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00360, C2DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 2 hits
PS51258, MHD1, 1 hit
PS51259, MHD2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform CImported (identifier: Q9VBY8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDEEQMWKGF FFKLQELKMN PPTEHEHQLQ DGDDGFFEKF GSLLRQKSQI
60 70 80 90 100
DEGVLKSSLA PLEENGSGGE EDSDESPDGT LQLSQDSECT SIDTFATEST
110 120 130 140 150
LASSSDKDIS TSVLDSAPVM NVTDLYEEIL FEIFNNIGCE NNEECTNSLV
160 170 180 190 200
EFVQDAFKIP NATHEEIYEA ARLKEPPNVR LNVEIIKAEN LMSKDSNGLS
210 220 230 240 250
DPFVTLYLES NGSHRYNSSV KPATLNPIWE EHFSLPITEN ARDEVLIVEV
260 270 280 290 300
WDFDAAETVK EKVNKILDVK GVKGLSKLMK EIAVTASSGK HDNELIGRAA
310 320 330 340 350
ITLKSIPVSG LTVWYNLEKG SKGRSRGSLL VNLALSAEKN KSVAVQEHKN
360 370 380 390 400
LLKLLLMYEL ETSQVANYWW SGKFSPNAEL IRSQHAAQSG LTPFDCALSQ
410 420 430 440 450
WHAYSTIHET HKLNFTLFNS ILDVVVPVIT YMQNDSEDVK TFWDGVKRLL
460 470 480 490 500
PSCFAVLRKL RSKNTSDKNI IRALNEVLDI LKKIKELEVP ESVDIFPKSV
510 520 530 540 550
YGWLHTNDTD ETCNIDTAIE DAINTGTREW LEHIVEGSRQ SKNTETDDEK
560 570 580 590 600
LQYVIKLIQM VRSDLQRAME YFDKIFYHKI QLNYSAVLYL FYDSKLAEIC
610 620 630 640 650
KSIIIEVCNN IKRLDVPDDQ FEYLPNLENV NMGTTLFEVY LILKRYVQLG
660 670 680 690 700
ESLCSEPLEL SNFYPWFERG VTHWLDISII KALSRIQKAI DLDQLKAVDE
710 720 730 740 750
TVKYSSSAVD TLSIFYQIKI FWQQLDWPEV EGSYIFVAKI VNDLCRCCIF
760 770 780 790 800
YAQQMSRRVE NIFIADDNNK NFILSEEWCI AINNMDYIRQ SLPSFIKELS
810 820 830 840 850
IDDIIKRLGE YRTNLEAERC ASTIKTVIEN ALDTERNQIV ELIEIVARKM
860 870 880 890 900
APPIRRYLAE GAEVLAKDSN SMDQLMMYLE SSLATLYDTL NEINFQRILD
910 920 930 940 950
GIWSELSIIM YDLIQSNLDK RRPPAFFQNL NNTLQTMMDC FKMGNLQTSD
960 970 980 990 1000
IKILSSIQSR LRLYSLETSD LIHQYYLERL ENQKSQESSP YGQLTITAQL
1010 1020 1030 1040 1050
TDTGLLLNIL NARNLLPMDS NGSVDSFVKA SFMPTSRFND VPTVKTNVHN
1060 1070 1080 1090 1100
KSCFPLYDQE FRINLSDHQR SEKNSLIVFS IKDKDLFGMS SQYIAESYIS
1110 1120 1130 1140 1150
FADLEATPPG EQIMMNLSRP EYTDSESLRA LEYRLGDKQA KDFLKKLKNR

SFS
Length:1,153
Mass (Da):131,921
Last modified:April 1, 2015 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37584AFC473FB456
GO
Isoform DImported (identifier: Q9VBY8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-121: MDEEQMWKGF...SVLDSAPVMN → MSYLSLPRVL...HAKAVCHSMT

Show »
Length:1,128
Mass (Da):129,350
Checksum:i7AADB4021904D693
GO
Isoform EImported (identifier: Q9VBY8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-28: MDEEQMWKGFFFKLQELKMNPPTEHEHQ → MLKSYFRRSELRIFEKIR

Show »
Length:1,143
Mass (Da):130,757
Checksum:i5E19D980C1C02CD3
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence ACU00262 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0585491 – 121MDEEQ…APVMN → MSYLSLPRVLSKFGSQNHSS SNQSSKTNSLTRSSTRTGCD EIRLPRKASSTQSLNKPFER RMSILNRNGSISSRHFRGVH KHLLDSHAKAVCHSMT in isoform D. Add BLAST121
Alternative sequenceiVSP_0585501 – 28MDEEQ…EHEHQ → MLKSYFRRSELRIFEKIR in isoform E. Add BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56388.5
AE014297 Genomic DNA Translation: ABW08753.2
AE014297 Genomic DNA Translation: AGB96327.1
BT032798 mRNA Translation: ACD81812.1
BT089029 mRNA Translation: ACU00262.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_001097909.2, NM_001104439.3 [Q9VBY8-2]
NP_001262947.1, NM_001276018.1 [Q9VBY8-3]
NP_651329.4, NM_143072.4 [Q9VBY8-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0303025; FBpp0292144; FBgn0266719 [Q9VBY8-1]
FBtr0303026; FBpp0292145; FBgn0266719 [Q9VBY8-2]
FBtr0334505; FBpp0306572; FBgn0266719 [Q9VBY8-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
43002

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG34349

UCSC genome browser

More...
UCSCi
CG34349-RA, d. melanogaster [Q9VBY8-1]
CG34349-RB, d. melanogaster

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56388.5
AE014297 Genomic DNA Translation: ABW08753.2
AE014297 Genomic DNA Translation: AGB96327.1
BT032798 mRNA Translation: ACD81812.1
BT089029 mRNA Translation: ACU00262.1 Different initiation.
RefSeqiNP_001097909.2, NM_001104439.3 [Q9VBY8-2]
NP_001262947.1, NM_001276018.1 [Q9VBY8-3]
NP_651329.4, NM_143072.4 [Q9VBY8-1]

3D structure databases

SMRiQ9VBY8
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0292144

Proteomic databases

PaxDbiQ9VBY8
PRIDEiQ9VBY8

Genome annotation databases

EnsemblMetazoaiFBtr0303025; FBpp0292144; FBgn0266719 [Q9VBY8-1]
FBtr0303026; FBpp0292145; FBgn0266719 [Q9VBY8-2]
FBtr0334505; FBpp0306572; FBgn0266719 [Q9VBY8-3]
GeneIDi43002
KEGGidme:Dmel_CG34349
UCSCiCG34349-RA, d. melanogaster [Q9VBY8-1]
CG34349-RB, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6769
FlyBaseiFBgn0266719, stac

Phylogenomic databases

eggNOGiKOG1328, Eukaryota
GeneTreeiENSGT00730000110939
HOGENOMiCLU_003295_0_0_1
InParanoidiQ9VBY8
OMAiFYQIKVF
PhylomeDBiQ9VBY8

Enzyme and pathway databases

ReactomeiR-DME-6798695, Neutrophil degranulation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
43002, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
43002

Protein Ontology

More...
PROi
PR:Q9VBY8

Gene expression databases

BgeeiFBgn0266719, Expressed in crop (Drosophila) and 38 other tissues
GenevisibleiQ9VBY8, DM

Family and domain databases

Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR014770, Munc13_1
IPR014772, Munc13_dom-2
PfamiView protein in Pfam
PF00168, C2, 2 hits
PRINTSiPR00360, C2DOMAIN
SMARTiView protein in SMART
SM00239, C2, 2 hits
PROSITEiView protein in PROSITE
PS50004, C2, 2 hits
PS51258, MHD1, 1 hit
PS51259, MHD2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUN13B_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VBY8
Secondary accession number(s): A0A0B4KHI5
, A8JRA6, B3DN10, C6SV37
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2016
Last sequence update: April 1, 2015
Last modified: August 12, 2020
This is version 143 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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