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UniProtKB - Q9VBP5 (Q9VBP5_DROME)

Entry version 170 (25 May 2022)
Sequence version 1 (01 May 2000)
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Protein
Submitted name:

Jing interacting gene regulatory 1, isoform A

Gene

jigr1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Jing interacting gene regulatory 1, isoform AImported
Submitted name:
Jing interacting gene regulatory 1, isoform BImported
Submitted name:
Jing interacting gene regulatory 1, isoform CImported
Submitted name:
Jing interacting gene regulatory 1, isoform DImported
Submitted name:
Jing interacting gene regulatory 1, isoform EImported
Submitted name:
Jing interacting gene regulatory 1, isoform FImported
Submitted name:
Jing interacting gene regulatory 1, isoform GImported
Submitted name:
Jing interacting gene regulatory 1, isoform HImported
Submitted name:
LD33329pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:jigr1Imported
Synonyms:bs29f05.y1Imported, Dmel\CG17383Imported, JIGR-1Imported, JIGR1Imported, sonImported
ORF Names:CG17383Imported, Dmel_CG17383Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0039350, jigr1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		VectorBase:FBgn0039350

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0039350, Expressed in embryo and 52 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9VBP5
With#Exp.IntAct
itself3EBI-176658,EBI-176658

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q9VBP5, 11 interactors

STRING: functional protein association networks

More...STRINGi		7227.FBpp0084260

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini32 – 118MADFInterPro annotationAdd BLAST87

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20
Regioni128 – 147DisorderedSequence analysisAdd BLAST20
Regioni180 – 202DisorderedSequence analysisAdd BLAST23
Regioni226 – 253DisorderedSequence analysisAdd BLAST28
Regioni306 – 336DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi180 – 198Polar residuesSequence analysisAdd BLAST19
Compositional biasi234 – 249Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi311 – 325Basic and acidic residuesSequence analysisAdd BLAST15

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0381, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000171161

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_767844_0_0_1

Identification of Orthologs from Complete Genome Data

More...OMAi		GYNHFAE

Database of Orthologous Groups

More...OrthoDBi		1207819at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006578, MADF-dom
IPR039353, TF_Adf1

The PANTHER Classification System

More...PANTHERi		PTHR12243, PTHR12243, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10545, MADF_DNA_bdg, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00595, MADF, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51029, MADF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VBP5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENLSHLYPP QLPKGRGRPR ATYAQTGEFD LGLIREYRSH PVLYDRSNKR 
        60         70         80         90        100
FKDKLYVAHI WEQIAHKLGY DATSIRERMT TLRNRYNIEK RRVENGLSTQ 
       110        120        130        140        150
SSQWPLFESL QFLGDHIRPR RSFKNMSVKE EDEETYEVDD CRSDSNGHMN 
       160        170        180        190        200
SIKDELEDDS EIFDCEQALP VTTVLGIPLN NSDEANKSQR STNGEMPNGK 
       210        220        230        240        250
GYNHFAESYH RRHQNQPEYI ISSPIVNPMR SNKRGSQHLD DHPSKRRVDD 
       260        270        280        290        300
SLSISGYYPT QPLAPLPPAY AKFRGFGEFM CHSLCDMPAA TALRLVQKFT 
       310        320        330 
RELVQSSLRN EDSGSKEKTD EVDPVDQSSE SQEEDE
Length:336
Mass (Da):38,776
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i615C3A7D14533383
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56484.1
AE014297 Genomic DNA Translation: AAF56485.1
AY075409 mRNA Translation: AAL68234.1
AE014297 Genomic DNA Translation: AAN14060.1
AE014297 Genomic DNA Translation: AAN14061.1
AE014297 Genomic DNA Translation: ABW08760.1
AE014297 Genomic DNA Translation: ABW08761.1
AE014297 Genomic DNA Translation: AGB96342.1
AE014297 Genomic DNA Translation: API64947.1

NCBI Reference Sequences

More...RefSeqi		NP_001097920.1, NM_001104450.2
NP_001097921.1, NM_001104451.2
NP_001262962.1, NM_001276033.1
NP_001334702.1, NM_001347754.1
NP_651409.1, NM_143152.4
NP_733112.1, NM_170233.2
NP_733113.1, NM_170234.1
NP_733114.1, NM_170235.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0084886; FBpp0084260; FBgn0039350
FBtr0084887; FBpp0084261; FBgn0039350
FBtr0084888; FBpp0084262; FBgn0039350
FBtr0084889; FBpp0084263; FBgn0039350
FBtr0113287; FBpp0112199; FBgn0039350
FBtr0113288; FBpp0112200; FBgn0039350
FBtr0336450; FBpp0307556; FBgn0039350
FBtr0445401; FBpp0401569; FBgn0039350

Database of genes from NCBI RefSeq genomes

More...GeneIDi		43093

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG17383

UCSC genome browser

More...UCSCi		CG17383-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56484.1
AE014297 Genomic DNA Translation: AAF56485.1
AY075409 mRNA Translation: AAL68234.1
AE014297 Genomic DNA Translation: AAN14060.1
AE014297 Genomic DNA Translation: AAN14061.1
AE014297 Genomic DNA Translation: ABW08760.1
AE014297 Genomic DNA Translation: ABW08761.1
AE014297 Genomic DNA Translation: AGB96342.1
AE014297 Genomic DNA Translation: API64947.1
RefSeqiNP_001097920.1, NM_001104450.2
NP_001097921.1, NM_001104451.2
NP_001262962.1, NM_001276033.1
NP_001334702.1, NM_001347754.1
NP_651409.1, NM_143152.4
NP_733112.1, NM_170233.2
NP_733113.1, NM_170234.1
NP_733114.1, NM_170235.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9VBP5, 11 interactors
STRINGi7227.FBpp0084260

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		43093

Genome annotation databases

EnsemblMetazoaiFBtr0084886; FBpp0084260; FBgn0039350
FBtr0084887; FBpp0084261; FBgn0039350
FBtr0084888; FBpp0084262; FBgn0039350
FBtr0084889; FBpp0084263; FBgn0039350
FBtr0113287; FBpp0112199; FBgn0039350
FBtr0113288; FBpp0112200; FBgn0039350
FBtr0336450; FBpp0307556; FBgn0039350
FBtr0445401; FBpp0401569; FBgn0039350
GeneIDi43093
KEGGidme:Dmel_CG17383
UCSCiCG17383-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		43093
FlyBaseiFBgn0039350, jigr1
VEuPathDBiVectorBase:FBgn0039350

Phylogenomic databases

eggNOGiKOG0381, Eukaryota
GeneTreeiENSGT00940000171161
HOGENOMiCLU_767844_0_0_1
OMAiGYNHFAE
OrthoDBi1207819at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		43093, 0 hits in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		jigr1, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		43093

Gene expression databases

BgeeiFBgn0039350, Expressed in embryo and 52 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR006578, MADF-dom
IPR039353, TF_Adf1
PANTHERiPTHR12243, PTHR12243, 1 hit
PfamiView protein in Pfam
PF10545, MADF_DNA_bdg, 1 hit
SMARTiView protein in SMART
SM00595, MADF, 1 hit
PROSITEiView protein in PROSITE
PS51029, MADF, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VBP5_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VBP5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 25, 2022
This is version 170 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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