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Entry version 168 (03 Jul 2019)
Sequence version 1 (01 May 2000)
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Protein

Poly [ADP-ribose] polymerase tankyrase

Gene

Tnks

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Stimulates proteasome activity, probably by ADP-ribosylation of PI31 (PubMed:23622245). Modulates 26S proteasome assembly (PubMed:23622245).1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi1091ZincBy similarity1
Metal bindingi1094ZincBy similarity1
Metal bindingi1099ZincBy similarity1
Metal bindingi1102ZincBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
LigandMetal-binding, NAD, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-201681 TCF dependent signaling in response to WNT
R-DME-4641257 Degradation of AXIN
R-DME-5689880 Ub-specific processing proteases
R-DME-8948751 Regulation of PTEN stability and activity

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9VBP3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Poly [ADP-ribose] polymerase tankyrase (EC:2.4.2.301 Publication)
Short name:
dTNKS1 Publication
Alternative name(s):
Poly [ADP-ribose] polymerase
Protein poly-ADP-ribosyltransferase tankyraseCurated (EC:2.4.2.-By similarity)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TnksImported
Synonyms:tankyraseImported
ORF Names:CG4719
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0027508 Tnks

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004248921 – 1181Poly [ADP-ribose] polymerase tankyraseAdd BLAST1181

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VBP3

PRoteomics IDEntifications database

More...
PRIDEi
Q9VBP3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0027508 Expressed in 29 organ(s), highest expression level in head

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VBP3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VBP3 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via ANK repeats) with PI31.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
PI31Q9V6373EBI-124451,EBI-144377

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
68007, 19 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VBP3, 6 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0084264

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VBP3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati56 – 85ANK 1Sequence analysisAdd BLAST30
Repeati89 – 118ANK 2Sequence analysisAdd BLAST30
Repeati122 – 151ANK 3Sequence analysisAdd BLAST30
Repeati209 – 238ANK 4Sequence analysisAdd BLAST30
Repeati242 – 271ANK 5Sequence analysisAdd BLAST30
Repeati275 – 304ANK 6Sequence analysisAdd BLAST30
Repeati362 – 394ANK 7Sequence analysisAdd BLAST33
Repeati398 – 427ANK 8Sequence analysisAdd BLAST30
Repeati431 – 458ANK 9Sequence analysisAdd BLAST28
Repeati483 – 513ANK 10Sequence analysisAdd BLAST31
Repeati519 – 548ANK 11Sequence analysisAdd BLAST30
Repeati552 – 581ANK 12Sequence analysisAdd BLAST30
Repeati585 – 614ANK 13Sequence analysisAdd BLAST30
Repeati638 – 668ANK 14Sequence analysisAdd BLAST31
Repeati672 – 701ANK 15Sequence analysisAdd BLAST30
Repeati705 – 734ANK 16Sequence analysisAdd BLAST30
Repeati738 – 767ANK 17Sequence analysisAdd BLAST30
Repeati771 – 799ANK 18Sequence analysisAdd BLAST29
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini889 – 952SAMPROSITE-ProRule annotationAdd BLAST64
Domaini969 – 1174PARP catalyticPROSITE-ProRule annotationAdd BLAST206

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4177 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000171680

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VBP3

KEGG Orthology (KO)

More...
KOi
K10799

Identification of Orthologs from Complete Genome Data

More...
OMAi
FHCVSQG

Database of Orthologous Groups

More...
OrthoDBi
1115202at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VBP3

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 6 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 1 hit
1.25.40.20, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR012317 Poly(ADP-ribose)pol_cat_dom
IPR001660 SAM
IPR013761 SAM/pointed_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023 Ank, 3 hits
PF12796 Ank_2, 3 hits
PF00644 PARP, 1 hit
PF07647 SAM_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 17 hits
SM00454 SAM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769 SSF47769, 1 hit
SSF48403 SSF48403, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 14 hits
PS51059 PARP_CATALYTIC, 1 hit
PS50105 SAM_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VBP3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANSSRSRAI LSVNLDAVMA NDPLRELFEA CKTGEIAKVK KLITPQTVNA
60 70 80 90 100
RDTAGRKSTP LHFAAGYGRR EVVEFLLNSG ASIQACDEGG LHPLHNCCSF
110 120 130 140 150
GHAEVVRLLL KAGASPNTTD NWNYTPLHEA ASKGKVDVCL ALLQHGANHT
160 170 180 190 200
IRNSEQKTPL ELADEATRPV LTGEYRKDEL LEAARSGAED RLLALLTPLN
210 220 230 240 250
VNCHASDGRR STPLHLAAGY NRIGIVEILL ANGADVHAKD KGGLVPLHNA
260 270 280 290 300
CSYGHFDVTK LLIQAGANVN ANDLWAFTPL HEAASKSRVE VCSLLLSRGA
310 320 330 340 350
DPTLLNCHSK SAIDAAPTRE LRERIAFEYK GHCLLDACRK CDVSRAKKLV
360 370 380 390 400
CAEIVNFVHP YTGDTPLHLA VVSPDGKRKQ LMELLTRKGS LLNEKNKAFL
410 420 430 440 450
TPLHLAAELL HYDAMEVLLK QGAKVNALDS LGQTPLHRCA RDEQAVRLLL
460 470 480 490 500
SYAADTNIVS LEGLTAAQLA SDSVLKLLKN PPDSETHLLE AAKAGDLDTV
510 520 530 540 550
RRIVLNNPIS VNCRDLDGRH STPLHFAAGF NRVPVVQFLL EHGAEVYAAD
560 570 580 590 600
KGGLVPLHNA CSYGHYEVTE LLVKHGANVN VSDLWKFTPL HEAAAKGKYD
610 620 630 640 650
ICKLLLKHGA DPMKKNRDGA TPADLVKESD HDVAELLRGP SALLDAAKKG
660 670 680 690 700
NLARVQRLVT PESINCRDAQ GRNSTPLHLA AGYNNFECAE YLLENGADVN
710 720 730 740 750
AQDKGGLIPL HNASSYGHLD IAALLIKHKT VVNATDKWGF TPLHEAAQKG
760 770 780 790 800
RTQLCSLLLA HGADAYMKNQ EGQTPIELAT ADDVKCLLQD AMATSLSQQA
810 820 830 840 850
LSASTQSLTS SSPAPDATAA AAPGTSSSSS SAILSPTTET VLLPTGASMI
860 870 880 890 900
LSVPVPLPLS SSTRISPAQG AEANGAEGSS SDDLLPDADT ITNVSGFLSS
910 920 930 940 950
QQLHHLIELF EREQITLDIL AEMGHDDLKQ VGVSAYGFRH KILKGIAQLR
960 970 980 990 1000
STTGIGNNVN LCTLLVDLLP DDKEFVAVEE EMQATIREHR DNGQAGGYFT
1010 1020 1030 1040 1050
RYNIIRVQKV QNRKLWERYA HRRQEIAEEN FLQSNERMLF HGSPFINAIV
1060 1070 1080 1090 1100
QRGFDERHAY IGGMFGAGIY FAEHSSKSNQ YVYGIGGGIG CPSHKDKSCY
1110 1120 1130 1140 1150
VCPRQLLLCR VALGKSFLQY SAMKMAHAPP GHHSVVGRPS AGGLHFAEYV
1160 1170 1180
VYRGEQSYPE YLITYQIVKP DDSSSGTEDT R
Length:1,181
Mass (Da):127,945
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEB6F0F94E6A3D504
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4KI19A0A0B4KI19_DROME
Poly [ADP-ribose] polymerase
Tnks BcDNA:LD22548, CG17487, CG4719, dARTD5, Dm.pARTb
1,520Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti28F → S in AAD34784 (PubMed:10731138).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56487.1
AF132196 mRNA Translation: AAD34784.1
BT044171 mRNA Translation: ACH92236.1

NCBI Reference Sequences

More...
RefSeqi
NP_651410.1, NM_143153.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0084890; FBpp0084264; FBgn0027508

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
43095

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG4719

UCSC genome browser

More...
UCSCi
CG4719-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56487.1
AF132196 mRNA Translation: AAD34784.1
BT044171 mRNA Translation: ACH92236.1
RefSeqiNP_651410.1, NM_143153.3

3D structure databases

SMRiQ9VBP3
ModBaseiSearch...

Protein-protein interaction databases

BioGridi68007, 19 interactors
IntActiQ9VBP3, 6 interactors
STRINGi7227.FBpp0084264

Proteomic databases

PaxDbiQ9VBP3
PRIDEiQ9VBP3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0084890; FBpp0084264; FBgn0027508
GeneIDi43095
KEGGidme:Dmel_CG4719
UCSCiCG4719-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8658
FlyBaseiFBgn0027508 Tnks

Phylogenomic databases

eggNOGiKOG4177 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000171680
InParanoidiQ9VBP3
KOiK10799
OMAiFHCVSQG
OrthoDBi1115202at2759
PhylomeDBiQ9VBP3

Enzyme and pathway databases

ReactomeiR-DME-201681 TCF dependent signaling in response to WNT
R-DME-4641257 Degradation of AXIN
R-DME-5689880 Ub-specific processing proteases
R-DME-8948751 Regulation of PTEN stability and activity
SignaLinkiQ9VBP3

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tnks fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
43095

Protein Ontology

More...
PROi
PR:Q9VBP3

Gene expression databases

BgeeiFBgn0027508 Expressed in 29 organ(s), highest expression level in head
ExpressionAtlasiQ9VBP3 baseline and differential
GenevisibleiQ9VBP3 DM

Family and domain databases

CDDicd00204 ANK, 6 hits
Gene3Di1.10.150.50, 1 hit
1.25.40.20, 5 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR012317 Poly(ADP-ribose)pol_cat_dom
IPR001660 SAM
IPR013761 SAM/pointed_sf
PfamiView protein in Pfam
PF00023 Ank, 3 hits
PF12796 Ank_2, 3 hits
PF00644 PARP, 1 hit
PF07647 SAM_2, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 17 hits
SM00454 SAM, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
SSF48403 SSF48403, 3 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 14 hits
PS51059 PARP_CATALYTIC, 1 hit
PS50105 SAM_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTNKS_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VBP3
Secondary accession number(s): Q9XZ37
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 22, 2014
Last sequence update: May 1, 2000
Last modified: July 3, 2019
This is version 168 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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