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Protein

Palmitoyltransferase

Gene

CG17197-PA

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:CG17197-PAImported
Synonyms:Dmel\CG17197Imported
ORF Names:CG17197Imported, Dmel_CG17197Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039367 CG17197

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 48HelicalUniRule annotationAdd BLAST22
Transmembranei60 – 81HelicalUniRule annotationAdd BLAST22
Transmembranei149 – 173HelicalUniRule annotationAdd BLAST25
Transmembranei193 – 215HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0039367

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0288643

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 230DHHCInterPro annotationAdd BLAST130

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311 Eukaryota
COG5273 LUCA
GeneTreeiENSGT00850000132405
KOiK18932
OMAiRSWHCIL
OrthoDBiEOG091G0RWR

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VBM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCLIWACTKY LARRNPKIFV RISHPTAVLF VIVTTIFFVV LQMFYVVPQL
60 70 80 90 100
FDVQGFMYKL GWLVAIFITY NIFGNMLACH ITSTSVESLP KDRQIPEPEE
110 120 130 140 150
EHQWHYCDVC EKLMPPRSWH CILCKCCILK RDRHCIFTAS CVGHNNQRYF
160 170 180 190 200
FWFTLFMALG TGVALATHII ATLKYFSYSD LIFLNIPRDN LPPFWLVITL
210 220 230 240 250
ILNTYVFAAP VSSVLMQLSV LKNNGTLHKF YSDTYDLGLW ENFKLILGGK
260 270 280 290
GFWTFLSPTV KSPLPHDGAQ WKIKRVQHHS PKLQFLRVSD
Length:290
Mass (Da):33,713
Last modified:March 3, 2009 - v2
Checksum:i055CA86449AB74BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56503.2
BT022181 mRNA Translation: AAY51575.1
RefSeqiNP_651425.2, NM_143168.4

Genome annotation databases

EnsemblMetazoaiFBtr0290204; FBpp0288643; FBgn0039367
GeneIDi43111
KEGGidme:Dmel_CG17197
UCSCiCG17197-RB d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VBM7_DROME
AccessioniPrimary (citable) accession number: Q9VBM7
Secondary accession number(s): Q4V6X5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: March 3, 2009
Last modified: June 20, 2018
This is version 141 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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