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Protein

Palmitoyltransferase

Gene

CG17195-PA

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:CG17195-PAImported
Synonyms:Dmel\CG17195Imported
ORF Names:CG17195Imported, Dmel_CG17195Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039369 CG17195

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 46HelicalUniRule annotationAdd BLAST25
Transmembranei58 – 79HelicalUniRule annotationAdd BLAST22
Transmembranei147 – 171HelicalUniRule annotationAdd BLAST25
Transmembranei205 – 224HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9VBM5

Expressioni

Gene expression databases

BgeeiFBgn0039369

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0084295

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 235DHHCInterPro annotationAdd BLAST133

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311 Eukaryota
COG5273 LUCA
GeneTreeiENSGT00850000132405
KOiK18932
OMAiACYMTSS
OrthoDBiEOG091G0RWR

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VBM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCYVNRFCHY FANRYPKNFV RIVHPLSIVF VLCSTAFFFS LQMFYIAPKV
60 70 80 90 100
FGDIAYKLYW ILVTFITHNI LGNMLACYMT SSSVNTLSKD SRCPNPEDEP
110 120 130 140 150
LWHYCESCKK LRSPRSWHCV LCNTCILRRD HHCIFTGTCI GHNNQRFFFW
160 170 180 190 200
FTFYLTLGLV TSFATFCMFI LQNGGNFMSL SSVIFNLITR TFFQNYTGNT
210 220 230 240 250
FETIAFLLNI SASYMPAFML AYQMQILSQN STYYNIFDCT YDLGFRKNCQ
260 270 280
TIMGQRGLWT FISPLLKSPL PHDGAHWQMK QSH
Length:283
Mass (Da):33,147
Last modified:February 7, 2006 - v2
Checksum:iC5571F3E47BA2D2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56505.2
BT022183 mRNA Translation: AAY51577.1
RefSeqiNP_651427.2, NM_143170.2
UniGeneiDm.25011

Genome annotation databases

EnsemblMetazoaiFBtr0084921; FBpp0084295; FBgn0039369
GeneIDi43113
KEGGidme:Dmel_CG17195
UCSCiCG17195-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VBM5_DROME
AccessioniPrimary (citable) accession number: Q9VBM5
Secondary accession number(s): Q4V6X3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: February 7, 2006
Last modified: July 18, 2018
This is version 139 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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