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UniProtKB - Q9VBH3 (Q9VBH3_DROME)
Protein
Submitted name:
Dysfusion, isoform D
Gene
dysf
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: FlyBase
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein heterodimerization activity Source: FlyBase
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: FlyBase
GO - Biological processi
- branch fusion, open tracheal system Source: FlyBase
- epithelial cell migration, open tracheal system Source: FlyBase
- imaginal disc-derived leg joint morphogenesis Source: FlyBase
- positive regulation of transcription by RNA polymerase II Source: FlyBase
- regulation of transcription, DNA-templated Source: FlyBase
- regulation of transcription by RNA polymerase II Source: FlyBase
Names & Taxonomyi
Protein namesi | Submitted name: Dysfusion, isoform DImported |
Gene namesi | Name:dysfImported Synonyms:CG12561Imported, CG14552Imported, CG14553Imported, CG14554Imported, Dmel\CG32474Imported, dNXFLImported, DysImported, dysImported, DYSFImported, DysfImported, NXFLImported ORF Names:CG32474Imported, Dmel_CG32474Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0039411, dysf |
VEuPathDBi | VectorBase:FBgn0039411 |
Subcellular locationi
Nucleus
- nucleus Source: FlyBase
Other locations
- protein-containing complex Source: FlyBase
Expressioni
Gene expression databases
Bgeei | FBgn0039411, Expressed in embryonic leading edge cell (Drosophila) and 35 other tissues |
ExpressionAtlasi | Q9VBH3, baseline and differential |
Genevisiblei | Q9VBH3, DM |
Interactioni
GO - Molecular functioni
- protein heterodimerization activity Source: FlyBase
Protein-protein interaction databases
IntActi | Q9VBH3, 4 interactors |
STRINGi | 7227.FBpp0289845 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 152 – 205 | BHLHInterPro annotationAdd BLAST | 54 | |
Domaini | 234 – 297 | PASInterPro annotationAdd BLAST | 64 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 55 – 145 | DisorderedSequence analysisAdd BLAST | 91 | |
Regioni | 291 – 333 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 551 – 612 | DisorderedSequence analysisAdd BLAST | 62 | |
Regioni | 647 – 675 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 821 – 849 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 861 – 883 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 898 – 920 | DisorderedSequence analysisAdd BLAST | 23 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 55 – 95 | Polar residuesSequence analysisAdd BLAST | 41 | |
Compositional biasi | 105 – 145 | Polar residuesSequence analysisAdd BLAST | 41 | |
Compositional biasi | 291 – 308 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 555 – 569 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 585 – 608 | Basic residuesSequence analysisAdd BLAST | 24 | |
Compositional biasi | 655 – 669 | Pro residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 824 – 849 | Polar residuesSequence analysisAdd BLAST | 26 |
Phylogenomic databases
eggNOGi | ENOG502QRXX, Eukaryota |
GeneTreei | ENSGT00530000064165 |
InParanoidi | Q9VBH3 |
PhylomeDBi | Q9VBH3 |
Family and domain databases
CDDi | cd00130, PAS, 2 hits |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR000014, PAS IPR035965, PAS-like_dom_sf |
SMARTi | View protein in SMART SM00091, PAS, 2 hits |
SUPFAMi | SSF55785, SSF55785, 2 hits |
TIGRFAMsi | TIGR00229, sensory_box, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit PS50112, PAS, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q9VBH3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPNAIGASSI TKWISQIESF EQRELVTNIC KRAIDDMYAD NKRGLDKVTA
60 70 80 90 100
ATPPTHALQQ QQQQQHPHQQ QQHLQHVLQL QQQQQQHLQQ QQHHLQHQMH
110 120 130 140 150
THHNFQQHET SPTVSQQQHM QQQQPQTTQQ QHATQQQQQQ QQQTAGMFTR
160 170 180 190 200
FDANKSTKGA SKMRRDLINA EIANLRDLLP LPQSTRQRLS QLQLMALVCV
210 220 230 240 250
YVRKANYFQQ VFKRHNAMHH LHHQTATPNI GFSKALSGFL MMLTQNGKLL
260 270 280 290 300
YISDNAAEYL GHSMEDLLIH GDSVYDIIDK QDHANIQAEL NRNVPPQPGG
310 320 330 340 350
SSQASSGGAG GAGGAGDSTS SNGSAAGAGG AGGASSLEGE HRMFLCRMNV
360 370 380 390 400
SRNARRQMRF GDQKVVLVQG HYLSFLPLCS RNEPVFLATC TPIAMPETRE
410 420 430 440 450
CVVQGATNVF TTIHSMDMKI AHIDKNGEFH LGYDKSTLQG TSWYNLIHSD
460 470 480 490 500
NLTEAQKKHS LIIQSEQDRS CILLVRMQRS SGEYTWVHVV LQVRDSPDST
510 520 530 540 550
QQPVIVCTNQ VLNDREASIM LANSWLYHYY TVQSKIQFGM PLDSGIRVPP
560 570 580 590 600
GTPSSGYYSP HSSHPPATPG GATPNLGIAS SFGPHHHPHH SHHPHHHHHH
610 620 630 640 650
HHPATAYHHH PHMGTYGGVY HAKAAIELKE DQPLFCFQEP VDYSQVNSHV
660 670 680 690 700
NPPNATSTPN PPISKSSTPP PPKKRARKLE PLYLHAERSP AAAITPEPDC
710 720 730 740 750
YAIHTHPAAA YATSSVVSSD ASVIYATIVP TRPRLPNKSL PPDPADFIEQ
760 770 780 790 800
WNPSPPWSES AQKASLDSFG SSHELSPCIT TTPPTPTSAT PHQSGLGTTQ
810 820 830 840 850
TIGPAFSFEW MSDPLVPVTY QQWPPTGDHH QHLSQHLSQS QNHQNPLQQQ
860 870 880 890 900
QNEQLLLGQQ PHLHQQHQHL ALHHGRGEHS LEGESQGVVV VPPIPISIPI
910 920
PTATGHGDAG EPVEDRDPKN
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA8JRD4 | A8JRD4_DROME | Dysfusion, isoform B | dysf CG12561, CG14552, CG14553, CG14554, Dmel\CG32474 | 884 | Annotation score: | ||
A8JRD5 | A8JRD5_DROME | Dysfusion, isoform C | dysf CG12561, CG14552, CG14553, CG14554, Dmel\CG32474 | 917 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF56569.4 |
RefSeqi | NP_733137.3, NM_170258.4 |
Genome annotation databases
EnsemblMetazoai | FBtr0300618; FBpp0289845; FBgn0039411 |
GeneIDi | 43174 |
UCSCi | CG32474-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF56569.4 |
RefSeqi | NP_733137.3, NM_170258.4 |
3D structure databases
SMRi | Q9VBH3 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q9VBH3, 4 interactors |
STRINGi | 7227.FBpp0289845 |
Proteomic databases
PaxDbi | Q9VBH3 |
Genome annotation databases
EnsemblMetazoai | FBtr0300618; FBpp0289845; FBgn0039411 |
GeneIDi | 43174 |
UCSCi | CG32474-RA, d. melanogaster |
Organism-specific databases
CTDi | 8291 |
FlyBasei | FBgn0039411, dysf |
VEuPathDBi | VectorBase:FBgn0039411 |
Phylogenomic databases
eggNOGi | ENOG502QRXX, Eukaryota |
GeneTreei | ENSGT00530000064165 |
InParanoidi | Q9VBH3 |
PhylomeDBi | Q9VBH3 |
Miscellaneous databases
BioGRID-ORCSi | 43174, 0 hits in 1 CRISPR screen |
GenomeRNAii | 43174 |
Gene expression databases
Bgeei | FBgn0039411, Expressed in embryonic leading edge cell (Drosophila) and 35 other tissues |
ExpressionAtlasi | Q9VBH3, baseline and differential |
Genevisiblei | Q9VBH3, DM |
Family and domain databases
CDDi | cd00130, PAS, 2 hits |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR000014, PAS IPR035965, PAS-like_dom_sf |
SMARTi | View protein in SMART SM00091, PAS, 2 hits |
SUPFAMi | SSF55785, SSF55785, 2 hits |
TIGRFAMsi | TIGR00229, sensory_box, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit PS50112, PAS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VBH3_DROME | |
Accessioni | Q9VBH3Primary (citable) accession number: Q9VBH3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | November 30, 2010 | |
Last modified: | September 29, 2021 | |
This is version 175 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |