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Protein

Palmitoyltransferase

Gene

Dmel\CG5880

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Dmel\CG5880Imported
Synonyms:CG5880-RAImported
ORF Names:CG5880Imported, Dmel_CG5880Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039489 CG5880

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei62 – 84HelicalUniRule annotationAdd BLAST23
Transmembranei96 – 117HelicalUniRule annotationAdd BLAST22
Transmembranei182 – 201HelicalUniRule annotationAdd BLAST20
Transmembranei273 – 294HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9VB73

Expressioni

Gene expression databases

BgeeiFBgn0039489

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0084478

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini137 – 309DHHCInterPro annotationAdd BLAST173

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1313 Eukaryota
COG5273 LUCA
GeneTreeiENSGT00900000140969
KOiK18932
OMAiKNWKLFL
OrthoDBiEOG091G0FLT

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9VB73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRITWRGHS TQELLSILRL RWSYMKHCWH SLTFNAHMNS SYASDVCLTP
60 70 80 90 100
IFWFVDNYTH CLGPFFVVGV AALTTSVVSI AYWIGLPFWW AKSQLVTYFL
110 120 130 140 150
LIVGNWLLLN VVFHYVMAVI TPAGHPPEGV SLVEAVSMCG KCIAPKPPRT
160 170 180 190 200
HHCSICNRCI LKMDHHCPWL NNCVGYGNHR YFFLYMTYTT LGCLFLILFG
210 220 230 240 250
LEIGHKYLWL DHGENWTEIE PLEGQPVKFN LSGHIIPVTH PNEYDEFVLP
260 270 280 290 300
PAVHNLPTPI VDTDAASPGR RRALWFMAFT NVAVVLALGS LSIWHAKLIT
310 320 330 340 350
RGETSVEAHI NEAERKRHLQ QQRIYINPYN FGTKKNWKLF LGLVRGRSFW
360 370 380
RTVLLPSWHK PEGTGLSFHT VNDAPFEDEW P
Length:381
Mass (Da):43,802
Last modified:July 5, 2004 - v2
Checksum:i186911721D869F52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56670.2
BT126104 mRNA Translation: ADY17805.1
RefSeqiNP_651539.3, NM_143282.4
UniGeneiDm.1351

Genome annotation databases

EnsemblMetazoaiFBtr0085108; FBpp0084478; FBgn0039489
GeneIDi43268
KEGGidme:Dmel_CG5880
UCSCiCG5880-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ9VB73_DROME
AccessioniPrimary (citable) accession number: Q9VB73
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: July 5, 2004
Last modified: July 18, 2018
This is version 138 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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