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Protein
Submitted name:

Pickpocket 20, isoform A

Gene

ppk20

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Sodium channelUniRule annotationSAAS annotation
Biological processIon transport, Sodium transport, Transport
LigandSodium

Names & Taxonomyi

Protein namesi
Submitted name:
Pickpocket 20, isoform AImported
Gene namesi
Name:ppk20Imported
Synonyms:CG7577Imported, Dmel\CG7577Imported, PPK20Imported
ORF Names:CG7577Imported, Dmel_CG7577Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039676 ppk20

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei71 – 99HelicalSequence analysisAdd BLAST29
Transmembranei496 – 522HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9VAJ6
PRIDEiQ9VAJ6

Expressioni

Gene expression databases

BgeeiFBgn0039676 Expressed in 4 organ(s), highest expression level in embryo
ExpressionAtlasiQ9VAJ6 baseline and differential
GenevisibleiQ9VAJ6 DM

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0084832

Structurei

3D structure databases

ProteinModelPortaliQ9VAJ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294 Eukaryota
ENOG410ZNFK LUCA
GeneTreeiENSGT00540000071900
InParanoidiQ9VAJ6
OrthoDBiEOG091G05C3
PhylomeDBiQ9VAJ6

Family and domain databases

InterProiView protein in InterPro
IPR001873 ENaC
PANTHERiPTHR11690 PTHR11690, 1 hit
PfamiView protein in Pfam
PF00858 ASC, 1 hit
PRINTSiPR01078 AMINACHANNEL

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

Q9VAJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKGDNSVKP TEAAGFGDNE RCLADLLKVH FRSYCEKSTI HCVRYLYDSH
60 70 80 90 100
LHNLERFVVY PLFISTFNFK LYIIIVFRII WSMLLIISIG LSFFFYLLLS
110 120 130 140 150
ERFVSQKLQT VVHDPQFPVF LVPFPAVGIC TDNRINWNKL EAAKEQFLPT
160 170 180 190 200
NASVELVESF TVLVSRMETL RFGSYLSSLA ELEDDNLEAV GFVNLTELAI
210 220 230 240 250
FMTLQCSDIM VPKSCLWRSS SFNCCEYFVL EKTEFGFCLV FNSEVSPRSK
260 270 280 290 300
AIKQKEGNNF YPRHNAKAGQ STGLNFDLIL NESFRRPDSQ ANNNVYVSIC
310 320 330 340 350
QAPDQLNNVV YSITQNTETY VTVRPGLTWT DNTTRSIPPE RRNCLFADEQ
360 370 380 390 400
GELDANDSAK NFGKPFQLSN CLNRCHESYL IQLCNCSLPI FFLYNHRVPD
410 420 430 440 450
CNAVSLRCLA RHNDIFSYDK RRDEDALFSA TKLGMTCSCL VDCYLLDYYT
460 470 480 490 500
STTTLPLSAH KLPKDPHQKL FRVDVHYQVE TTPLYRTSLE FTIIDLIANL
510 520 530 540 550
GGIFGLCLGA SMVSAFELIY YLTVGLAMHL YDHQYYGVLF KHLKAKWVNL
560 570 580
KGYLRNEVGH LAENPAAHKD TNDRKLRHPF NYRKNVW
Length:587
Mass (Da):67,421
Last modified:April 26, 2005 - v2
Checksum:i20525B82054A9BB6
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4KHD5A0A0B4KHD5_DROME
Pickpocket 20, isoform B
ppk20 CG7577, Dmel\CG7577, PPK20, CG7577, Dmel_CG7577
564Annotation score:
A0A0B4KHV2A0A0B4KHV2_DROME
Pickpocket 20, isoform C
ppk20 CG7577, Dmel\CG7577, PPK20, CG7577, Dmel_CG7577
565Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56910.2
RefSeqiNP_651705.2, NM_143448.2
UniGeneiDm.16324

Genome annotation databases

EnsemblMetazoaiFBtr0085466; FBpp0084832; FBgn0039676
GeneIDi43486
UCSCiCG7577-RA d. melanogaster

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF56910.2
RefSeqiNP_651705.2, NM_143448.2
UniGeneiDm.16324

3D structure databases

ProteinModelPortaliQ9VAJ6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0084832

Proteomic databases

PaxDbiQ9VAJ6
PRIDEiQ9VAJ6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0085466; FBpp0084832; FBgn0039676
GeneIDi43486
UCSCiCG7577-RA d. melanogaster

Organism-specific databases

CTDi43486
FlyBaseiFBgn0039676 ppk20

Phylogenomic databases

eggNOGiKOG4294 Eukaryota
ENOG410ZNFK LUCA
GeneTreeiENSGT00540000071900
InParanoidiQ9VAJ6
OrthoDBiEOG091G05C3
PhylomeDBiQ9VAJ6

Miscellaneous databases

GenomeRNAii43486

Gene expression databases

BgeeiFBgn0039676 Expressed in 4 organ(s), highest expression level in embryo
ExpressionAtlasiQ9VAJ6 baseline and differential
GenevisibleiQ9VAJ6 DM

Family and domain databases

InterProiView protein in InterPro
IPR001873 ENaC
PANTHERiPTHR11690 PTHR11690, 1 hit
PfamiView protein in Pfam
PF00858 ASC, 1 hit
PRINTSiPR01078 AMINACHANNEL
ProtoNetiSearch...

Entry informationi

Entry nameiQ9VAJ6_DROME
AccessioniPrimary (citable) accession number: Q9VAJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: April 26, 2005
Last modified: September 12, 2018
This is version 128 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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