The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - Q9VA92 (Q9VA92_DROME)
Protein
Submitted name:
RH14937p
Gene
anon-WO0118547.264
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Cofactori
Fe2+UniRule annotation
GO - Molecular functioni
- iron ion binding Source: GO_Central
- stearoyl-CoA 9-desaturase activity Source: FlyBase
GO - Biological processi
- unsaturated fatty acid biosynthetic process Source: GO_Central
Keywordsi
Molecular function | OxidoreductaseUniRule annotationARBA annotation |
Biological process | Fatty acid biosynthesisUniRule annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Ligand | IronARBA annotation |
Enzyme and pathway databases
Reactomei | R-DME-75105, Fatty acyl-CoA biosynthesis |
Names & Taxonomyi
Protein namesi | Submitted name: RH14937pImported |
Gene namesi | Name:anon-WO0118547.264Imported Synonyms:Dmel\CG9743Imported ORF Names:CG9743Imported, Dmel_CG9743Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0039756, CG9743 |
VEuPathDBi | VectorBase:FBgn0039756 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 130 – 149 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 247 – 268 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 280 – 301 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | FBgn0039756, Expressed in adult midgut (Drosophila) and 62 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 133 – 335 | FA_desaturaseInterPro annotationAdd BLAST | 203 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 74 – 94 | Sequence analysisAdd BLAST | 21 |
Domaini
The histidine box domains are involved in binding the catalytic metal ions.UniRule annotation
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG1600, Eukaryota |
HOGENOMi | CLU_027359_0_1_1 |
OMAi | SFWVNFN |
OrthoDBi | 971318at2759 |
Family and domain databases
CDDi | cd03505, Delta9-FADS-like, 1 hit |
InterProi | View protein in InterPro IPR015876, Acyl-CoA_DS IPR005804, FA_desaturase_dom |
PANTHERi | PTHR11351, PTHR11351, 1 hit |
Pfami | View protein in Pfam PF00487, FA_desaturase, 1 hit |
PRINTSi | PR00075, FACDDSATRASE |
i Sequence
Sequence statusi: Complete.
Q9VA92-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCLSSPIPGQ KQATSVGHCN GSCSLDRNGN RSAAIVPNGG ELKHRGHATD
60 70 80 90 100
ATSHTLVKDD DNLGYKEENA VYKEQQLLQQ QDQTLKEAEQ VEEEEEYHPQ
110 120 130 140 150
IRWPDLGAQA FLHIGALYGL YQLFYANFYT FLWVVVTVWV SGIGITAGAH
160 170 180 190 200
RLWSHKSYTA SLPLRILLAF AFSIAGQRDA YTWALDHRIH HKFSETDADP
210 220 230 240 250
HNAKRGFFFA HVGWLFLTPH PKVVAKRKVI DMSDLEADAV CMFQRKYYIP
260 270 280 290 300
LFALCSIILP VAVPWYFWNE DLWMSFWINF NMRFTWTLNV AFFVNSVAHM
310 320 330 340 350
YGNKPYDKNL MSTEAPIVSL LAMGEGWHNY HHVFPWDYKT GEFGNYSLNI
360 370 380 390 400
TTGFIDFCAW LGLAKGRKSV SPDMVLRRAK KCGDGTRFLD DDHAHKDPVW
410 420
GFGDKDIPRE DIVELAKMQN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF57022.2 AY094910 mRNA Translation: AAM11263.1 |
RefSeqi | NP_651781.1, NM_143524.4 |
Genome annotation databases
EnsemblMetazoai | FBtr0085571; FBpp0084937; FBgn0039756 |
GeneIDi | 43593 |
KEGGi | dme:Dmel_CG9743 |
UCSCi | CG9743-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014297 Genomic DNA Translation: AAF57022.2 AY094910 mRNA Translation: AAM11263.1 |
RefSeqi | NP_651781.1, NM_143524.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7227.FBpp0084937 |
Protocols and materials databases
DNASUi | 43593 |
Genome annotation databases
EnsemblMetazoai | FBtr0085571; FBpp0084937; FBgn0039756 |
GeneIDi | 43593 |
KEGGi | dme:Dmel_CG9743 |
UCSCi | CG9743-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0039756, CG9743 |
VEuPathDBi | VectorBase:FBgn0039756 |
Phylogenomic databases
eggNOGi | KOG1600, Eukaryota |
HOGENOMi | CLU_027359_0_1_1 |
OMAi | SFWVNFN |
OrthoDBi | 971318at2759 |
Enzyme and pathway databases
Reactomei | R-DME-75105, Fatty acyl-CoA biosynthesis |
Miscellaneous databases
BioGRID-ORCSi | 43593, 0 hits in 3 CRISPR screens |
ChiTaRSi | CG9743, fly |
GenomeRNAii | 43593 |
Gene expression databases
Bgeei | FBgn0039756, Expressed in adult midgut (Drosophila) and 62 other tissues |
Family and domain databases
CDDi | cd03505, Delta9-FADS-like, 1 hit |
InterProi | View protein in InterPro IPR015876, Acyl-CoA_DS IPR005804, FA_desaturase_dom |
PANTHERi | PTHR11351, PTHR11351, 1 hit |
Pfami | View protein in Pfam PF00487, FA_desaturase, 1 hit |
PRINTSi | PR00075, FACDDSATRASE |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VA92_DROME | |
Accessioni | Q9VA92Primary (citable) accession number: Q9VA92 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | March 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 171 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |