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UniProtKB - Q9V9S0 (Q9V9S0_DROME)
Protein
Submitted name:
FI04419p
Gene
Lamp1
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Biological processi
- establishment of protein localization to organelle Source: GO_Central
- lipophagy Source: FlyBase
Enzyme and pathway databases
Reactomei | R-DME-114608, Platelet degranulation R-DME-6798695, Neutrophil degranulation |
Names & Taxonomyi
Protein namesi | Submitted name: FI04419pImportedSubmitted name: Lamp1Imported |
Gene namesi | Name:Lamp1Imported Synonyms:CG3305-RAImported, dLAMPImported, dLampImported, Dmel\CG3305Imported, LAMPImported, LampImported, Lamp-1Imported, LAMP1Imported, lamp1Imported ORF Names:CG3305Imported, Dmel_CG3305Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0032949, Lamp1 |
VEuPathDBi | VectorBase:FBgn0032949 |
Subcellular locationi
Endosome
- Endosome membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
- Membrane PROSITE-ProRule annotationARBA annotation; Single-pass type I membrane protein PROSITE-ProRule annotationARBA annotation
Endosome
- late endosome membrane Source: GO_Central
Lysosome
- lysosomal membrane Source: GO_Central
- lysosome Source: FlyBase
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-UniRule
- lipid droplet Source: FlyBase
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 283 – 306 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 25 | Sequence analysisAdd BLAST | 25 | |
ChainiPRO_5015100026 | 26 – 318 | Sequence analysisAdd BLAST | 293 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 115 ↔ 153 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondPROSITE-ProRule annotation, GlycoproteinARBA annotationExpressioni
Gene expression databases
Bgeei | FBgn0032949, Expressed in Malpighian tubule and 38 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9V9S0, 115 interactors |
STRINGi | 7227.FBpp0085251 |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 50 – 100 | DisorderedSequence analysisAdd BLAST | 51 |
Sequence similaritiesi
Keywords - Domaini
SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG4818, Eukaryota |
GeneTreei | ENSGT00950000182899 |
HOGENOMi | CLU_068123_0_0_1 |
OMAi | CIMLQMA |
OrthoDBi | 1229669at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR002000, Lysosome-assoc_membr_glycop |
PANTHERi | PTHR11506, PTHR11506, 1 hit |
Pfami | View protein in Pfam PF01299, Lamp, 1 hit |
PRINTSi | PR00336, LYSASSOCTDMP |
PROSITEi | View protein in PROSITE PS51407, LAMP_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9V9S0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFANKLLTCS ALLIMLFLLS STVFSQKLIG LPRVGKNVSD LFLEQANPLT
60 70 80 90 100
SSSSTISTSS TTTEKPITTR STSTITPRST TPSTESPSTT APVISTTIAP
110 120 130 140 150
QPYPQPSIGA WNTSCIMLQM AAQLNFTYEA REGNFTTGLY NIPSNASVED
160 170 180 190 200
AECKSQTTQF IHLIWGPETS KQSLIMYFNK SNDTTVLSFM QIHLALLPED
210 220 230 240 250
FPDAKENQTV QLITRSDGAF KTPENMSYHC TRVQKINMTE TLDAEQLIGW
260 270 280 290 300
ISVSHVQVEA FRRANDTGFS VGHDCDSSET SDVVPIAVGI ALAALILVVL
310
ISYLCARRRS TSRGYMSF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AAF57215.3 BT050563 mRNA Translation: ACJ23447.1 |
RefSeqi | NP_610111.3, NM_136267.5 |
Genome annotation databases
EnsemblMetazoai | FBtr0085896; FBpp0085251; FBgn0032949 |
GeneIDi | 35411 |
KEGGi | dme:Dmel_CG3305 |
UCSCi | CG3305-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AAF57215.3 BT050563 mRNA Translation: ACJ23447.1 |
RefSeqi | NP_610111.3, NM_136267.5 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9V9S0, 115 interactors |
STRINGi | 7227.FBpp0085251 |
Protocols and materials databases
DNASUi | 35411 |
Genome annotation databases
EnsemblMetazoai | FBtr0085896; FBpp0085251; FBgn0032949 |
GeneIDi | 35411 |
KEGGi | dme:Dmel_CG3305 |
UCSCi | CG3305-RA, d. melanogaster |
Organism-specific databases
CTDi | 3916 |
FlyBasei | FBgn0032949, Lamp1 |
VEuPathDBi | VectorBase:FBgn0032949 |
Phylogenomic databases
eggNOGi | KOG4818, Eukaryota |
GeneTreei | ENSGT00950000182899 |
HOGENOMi | CLU_068123_0_0_1 |
OMAi | CIMLQMA |
OrthoDBi | 1229669at2759 |
Enzyme and pathway databases
Reactomei | R-DME-114608, Platelet degranulation R-DME-6798695, Neutrophil degranulation |
Miscellaneous databases
BioGRID-ORCSi | 35411, 0 hits in 3 CRISPR screens |
ChiTaRSi | Lamp1, fly |
GenomeRNAii | 35411 |
Gene expression databases
Bgeei | FBgn0032949, Expressed in Malpighian tubule and 38 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR002000, Lysosome-assoc_membr_glycop |
PANTHERi | PTHR11506, PTHR11506, 1 hit |
Pfami | View protein in Pfam PF01299, Lamp, 1 hit |
PRINTSi | PR00336, LYSASSOCTDMP |
PROSITEi | View protein in PROSITE PS51407, LAMP_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9V9S0_DROME | |
Accessioni | Q9V9S0Primary (citable) accession number: Q9V9S0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | December 7, 2004 | |
Last modified: | January 19, 2022 | |
This is version 157 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |