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UniProtKB - Q9V468 (Y9776_DROME)

Entry version 141 (10 Feb 2021)
Sequence version 1 (01 May 2000)
Previous versions | rss
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Protein

Zinc finger matrin-type protein CG9776

Gene

CG9776

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri546 – 576Matrin-typeAdd BLAST31

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger matrin-type protein CG9776
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CG9776
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0027866, CG9776

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003728521 – 1260Zinc finger matrin-type protein CG9776Add BLAST1260

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei335Phosphoserine1 Publication1
Modified residuei338Phosphothreonine1 Publication1
Modified residuei697Phosphoserine1 Publication1
Modified residuei700Phosphothreonine1 Publication1
Modified residuei1197Phosphoserine1 Publication1
Modified residuei1228Phosphoserine1 Publication1
Modified residuei1232Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9V468

PRoteomics IDEntifications database

More...PRIDEi		Q9V468

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9V468

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0027866, Expressed in eye disc (Drosophila) and 38 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9V468, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9V468, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		65767, 21 interactors

Protein interaction database and analysis system

More...IntActi		Q9V468, 16 interactors

STRING: functional protein association networks

More...STRINGi		7227.FBpp0078595

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili285 – 366Sequence analysisAdd BLAST82

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi55 – 140Arg-richAdd BLAST86
Compositional biasi143 – 223Pro-richAdd BLAST81
Compositional biasi395 – 422Ser-richAdd BLAST28
Compositional biasi606 – 640Lys-richAdd BLAST35
Compositional biasi648 – 658Poly-SerAdd BLAST11
Compositional biasi713 – 717Poly-Pro5
Compositional biasi800 – 897Arg-richAdd BLAST98
Compositional biasi962 – 968Poly-Pro7
Compositional biasi1031 – 1036Poly-Pro6

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri546 – 576Matrin-typeAdd BLAST31

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502R1ZF, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000000614

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_006889_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9V468

Identification of Orthologs from Complete Genome Data

More...OMAi		CSVWIGD

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9V468

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9V468-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDEDSATIQL GDRRLGNAVD HDLLPGPPGV DEKSGNENCE PRSSGSGKRG 
        60         70         80         90        100
KSNSRRRSTS RGRSDSRNTS PSNTRRRHSL SRSLTPPRRR YDSPDYGRYS 
       110        120        130        140        150
RRRFDRDRRR SPERRRSPPR RGRRYGRSRS RSMSPRRGGR WSPKKKPSSP 
       160        170        180        190        200
PVPPPHGGPH PQMTPGYGAM AAHIYGSYVA PPDVYGHQYG IPPNSFPPQG 
       210        220        230        240        250
PGYGIPGAPP DQSSFGSGYG PPPTSAWDVN VYGQQVWINQ PISGVQPSAS 
       260        270        280        290        300
DSLIQPQKAR ETLSGKTIGE EQSVPALEGA GLTPQDAVAQ EAEKQKDELK 
       310        320        330        340        350
KQRANYVKKV SLLKKEMKVL KDQREDLAAG DAPPSPTTKN FIEENDRLQM 
       360        370        380        390        400
QIKKKLDTIE NVIDMLNGII GYEEVEDEPS NQKSHGKTQP EQQDSRSHSS 
       410        420        430        440        450
SESSADSSES SSSSSTASDS SSDNEDGEGA GGAVGSPTNR LKHRAIKSMK 
       460        470        480        490        500
SKQLHGEMKA VPTQAQNYNF VFFDPEQHWC ESCGVFPKSA RDYLKHLHAE 
       510        520        530        540        550
EHMNRETIET PWHVGIDHDP FPTFENAPAR RVPVRGMQFL VPANAWFCKL 
       560        570        580        590        600
CSVWIGDLHC ASAHLKSRLH SNKYQQFLNQ NPNYEIEWQT NRERAMNQQK 
       610        620        630        640        650
DHDDAKNKKS KKDEDKASKK RKKKGGDKKK KKRKHGKKSK RSTIDANSTS 
       660        670        680        690        700
SSSDSSSSEE ENGQQPKKGR TEQQPICQSD KSTNAASIRV AMRKQESTPT 
       710        720        730        740        750
NLKPEVPCQP VVPPPPPIIK DSTIPSERGK WTAASVEDQS KDQKNRDDTM 
       760        770        780        790        800
LKQWNNVQPV ISESEKKLLE QLKGRLKNKG ARDQNNHKAV PTEANDEKFR 
       810        820        830        840        850
RGGGRHSRSR SKRRSYSRSI SRGRDRDRRD RERDRDRGRR RRSRSRGRHF 
       860        870        880        890        900
SRSPIRSSRR SRSRQGRSRR SRSRSIERVE RPVVKHSEFR PRTVPERKQT 
       910        920        930        940        950
DIKRDKKDAE SKSKSSKPSN NSLPGGKKLP FIGKMPVFKK QSVPSFNYDA 
       960        970        980        990       1000
SAVYTNGCLE APPPPPPPLG GATSQIAVRQ QAPTAAQIQM AMMEDAFGNA 
      1010       1020       1030       1040       1050
PPFHPDAGMM VDYDELMPDP VQFANLMTSC PPPPPPGEGS EGDAHGPEDG 
      1060       1070       1080       1090       1100
DQHDNENRED VLPPGIDEAE SALVPHPLDA AAQSRDGELP KDLVEALDII 
      1110       1120       1130       1140       1150
FPSDVAILEA SNGNSEKQED VTITTIVEDD AVLSVIHLQD LAKEGIHLVT 
      1160       1170       1180       1190       1200
INEAEVPKKS HIQTSEKIEK LQDLNGKSDD GVNIKLIDAE DIPMPNSPPA 
      1210       1220       1230       1240       1250
EPSFDEETKS KALQKQADIS EIPEPAVSPS DSEKLRRQSE LDELAMLGID 
      1260
RSDMAAQYAL
Length:1,260
Mass (Da):140,295
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i098296D9FEA695CA
GO
Isoform 2 (identifier: Q9V468-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-574: Missing.
     575-575: Q → M
     1258-1260: YAL → CM

Show »
Length:685
Mass (Da):76,563
Checksum:iCAF0F370D71FF9C0
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0372061 – 574Missing in isoform 2. 1 PublicationAdd BLAST574
Alternative sequenceiVSP_037207575Q → M in isoform 2. 1 Publication1
Alternative sequenceiVSP_0372081258 – 1260YAL → CM in isoform 2. 1 Publication3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF52146.1
AE014297 Genomic DNA Translation: AAN13304.3
AF160940 mRNA Translation: AAD46880.1
BT001348 mRNA Translation: AAN71103.1

NCBI Reference Sequences

More...RefSeqi		NP_649455.1, NM_141198.4 [Q9V468-1]
NP_730813.3, NM_164339.4 [Q9V468-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0078955; FBpp0078595; FBgn0027866 [Q9V468-1]
FBtr0078956; FBpp0078596; FBgn0027866 [Q9V468-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		40546

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG9776

UCSC genome browser

More...UCSCi		CG9776-RA, d. melanogaster [Q9V468-1]
CG9776-RB, d. melanogaster

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF52146.1
AE014297 Genomic DNA Translation: AAN13304.3
AF160940 mRNA Translation: AAD46880.1
BT001348 mRNA Translation: AAN71103.1
RefSeqiNP_649455.1, NM_141198.4 [Q9V468-1]
NP_730813.3, NM_164339.4 [Q9V468-2]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi65767, 21 interactors
IntActiQ9V468, 16 interactors
STRINGi7227.FBpp0078595

PTM databases

iPTMnetiQ9V468

Proteomic databases

PaxDbiQ9V468
PRIDEiQ9V468

Genome annotation databases

EnsemblMetazoaiFBtr0078955; FBpp0078595; FBgn0027866 [Q9V468-1]
FBtr0078956; FBpp0078596; FBgn0027866 [Q9V468-2]
GeneIDi40546
KEGGidme:Dmel_CG9776
UCSCiCG9776-RA, d. melanogaster [Q9V468-1]
CG9776-RB, d. melanogaster

Organism-specific databases

FlyBaseiFBgn0027866, CG9776

Phylogenomic databases

eggNOGiENOG502R1ZF, Eukaryota
GeneTreeiENSGT00390000000614
HOGENOMiCLU_006889_0_0_1
InParanoidiQ9V468
OMAiCSVWIGD
PhylomeDBiQ9V468

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		40546, 1 hit in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		40546

Protein Ontology

More...PROi		PR:Q9V468

Gene expression databases

BgeeiFBgn0027866, Expressed in eye disc (Drosophila) and 38 other tissues
ExpressionAtlasiQ9V468, baseline and differential
GenevisibleiQ9V468, DM

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiY9776_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9V468
Secondary accession number(s): Q7JRP8, Q8I092
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 1, 2000
Last modified: February 10, 2021
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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