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Entry version 168 (16 Oct 2019)
Sequence version 1 (01 May 2000)
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Protein

Chromosomal serine/threonine-protein kinase JIL-1

Gene

JIL-1

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Phosphorylates 'Ser-10' of histone H3. May regulate gene expression by establishing or maintaining the structure of more open chromatin regions. Also required for normal polytene chromosome structure, for oogenesis and for viability throughout development. Regulates the structure of polytene chromosomes in salivary glands. May phosphorylate 'Ser-1' of histone H2A.5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei293ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei389Proton acceptorSequence analysis1
Binding sitei652ATPPROSITE-ProRule annotation1
Active sitei739Proton acceptorSequence analysis1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi267 – 275ATPPROSITE-ProRule annotation9
Nucleotide bindingi629 – 637ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • histone kinase activity (H3-S10 specific) Source: UniProtKB
  • protein serine/threonine kinase activity Source: FlyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase
Biological processTranscription, Transcription regulation
LigandATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-198753 ERK/MAPK targets
R-DME-199920 CREB phosphorylation
R-DME-375165 NCAM signaling for neurite out-growth
R-DME-5621575 CD209 (DC-SIGN) signaling

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9V3I5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chromosomal serine/threonine-protein kinase JIL-1 (EC:2.7.11.1)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:JIL-1Imported
ORF Names:CG6297
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0020412 JIL-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000860391 – 1207Chromosomal serine/threonine-protein kinase JIL-1Add BLAST1207

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei29Phosphoserine1 Publication1
Modified residuei31Phosphoserine1 Publication1
Modified residuei424Phosphoserine1 Publication1
Modified residuei588Phosphothreonine1 Publication1
Modified residuei1045Phosphothreonine1 Publication1
Modified residuei1047Phosphoserine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Autophosphorylated in vitro.2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9V3I5

PRoteomics IDEntifications database

More...
PRIDEi
Q9V3I5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9V3I5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0020412 Expressed in 28 organ(s), highest expression level in egg chamber

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9V3I5 differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9V3I5 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with lola.

Interacts with proteins of the male specific lethal (MSL) dosage compensation complex; this interaction is mediated by the kinase domains.

2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
64615, 13 interactors

Protein interaction database and analysis system

More...
IntActi
Q9V3I5, 106 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0304953

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9V3I5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini261 – 530Protein kinase 1PROSITE-ProRule annotationAdd BLAST270
Domaini531 – 599AGC-kinase C-terminalAdd BLAST69
Domaini623 – 886Protein kinase 2PROSITE-ProRule annotationAdd BLAST264

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi43 – 108Asn-richSequence analysisAdd BLAST66
Compositional biasi191 – 209Ala-richSequence analysisAdd BLAST19

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0598 Eukaryota
ENOG410XNPH LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000167362

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9V3I5

KEGG Orthology (KO)

More...
KOi
K04445

Identification of Orthologs from Complete Genome Data

More...
OMAi
VVQKRKT

Database of Orthologous Groups

More...
OrthoDBi
1132245at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9V3I5

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00069 Pkinase, 2 hits
PF00433 Pkinase_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112 SSF56112, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9V3I5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRLQKQNYE ILSGTSTSRL KNHQHPRESE SLAYEEPDQM VRNHLNGQLV
60 70 80 90 100
ANGNGKTRKN SNSETMTNGK KSKLNTEGSG SGSGKTLNYN NNNNNNNSIS
110 120 130 140 150
ATNGQYTNSS SKTTSASARD YTYRETISPP TPPSPPTTNV ADIVCISDAE
160 170 180 190 200
SEDGRDPERE YYDQDMEEDE PNGIEIDESS SSLSKAKSNN AAAAAAAAAA
210 220 230 240 250
AAAAAASKAS SSTTPSYAMP TSNSTPLDLD NEAHQRDLEA VTDLKYYVKL
260 270 280 290 300
YSDEAVSLND FKIIRVLGTG AYGRVFLVRK LTRHDAGKLY AMKVLNKITV
310 320 330 340 350
VQKRKTAEHT KTERVVLEAI QRNPFLVSLH YAFQSSSKLY LVLDFANGGE
360 370 380 390 400
LFTHLYHSEN FEESRVRVYI AEVVLALEQL HQLGIIYRDI KLENILLDGE
410 420 430 440 450
GHIVLSDFGL SKILTAENEY RAHSFCGTLE YMAPEIIRTG PPGHDSAVDW
460 470 480 490 500
WSVGVLTFEL LTGASPFATS DGQVQQSEIS RRIQKEQPMI PSSFSANARD
510 520 530 540 550
FVLKMLEKNP KRRLGGNHRD ASEIKEHPFF NGINWQELRT KRRKAPYKPT
560 570 580 590 600
LTAEDDVQNF SNEFTDQVPE DPECDAPPSR IRLFRGYTYV APEHLEQMRR
610 620 630 640 650
DNHCEIQYFN TGLQNIPCRP DDLELGTRTS NGAYGTCHFV VDSSTDLVFL
660 670 680 690 700
AKIIPLSKFR PSEVDALISC ALDTTNHKNI VSYHGTFREK CETWIVMEYL
710 720 730 740 750
SGPELTASIR MDEDSCREIF LQLVMAVRHI HSKHFIHGDL KPENIMFENR
760 770 780 790 800
EDRTVKLIDF GSACYNNRFK SWKDKPRYTL DYAPPEMLAD ANLVTYSPAV
810 820 830 840 850
DIYGLGATLY TMLVGHRPYR QNEDDVDHSA AAHHELRKRM RRGTFNQRSM
860 870 880 890 900
RWESASPAFR HLVSWCLQRD PADRPTLSDI LDSEWLQYGS NDPDVDIILP
910 920 930 940 950
QQMVVDLSED TMEQPTGGMF DDQQQLEFMH DKSAEDEGIT LVSEPMDTTV
960 970 980 990 1000
ATHESRRNAA AFSSVVAPTT DDEIVHERFD PAFEVQADFY GFDENAPPLP
1010 1020 1030 1040 1050
LPEEYYSELP LPEEDRQYIP PPPALIPVEP ETTFRRPRTR QQRRTESQLV
1060 1070 1080 1090 1100
QPVSVATYED SKASLRVLMQ QLPPPGDNVV ARIPKRTHRV VRTLPPTFGT
1110 1120 1130 1140 1150
TKREENFYGF SKTAISWRKT RASWRHFCLL INGVQQVLKV RFKKARRVYC
1160 1170 1180 1190 1200
LPHIKEEKLD HAYEKPLTFP RPKAQLKRTK REPKVPRPPT RVQPERARAM

RQLYQFQ
Length:1,207
Mass (Da):137,045
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBD99FB932D708743
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PI05M9PI05_DROME
Non-specific serine/threonine prote...
JIL-1 2Ab17, anon-WO0118547.379, Dmel\CG6297, IL-1, JIL
1,207Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAL28591 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF142061 mRNA Translation: AAD48407.1
AE014296 Genomic DNA Translation: AAF50105.1
AE014296 Genomic DNA Translation: AAN11898.1
BT044484 mRNA Translation: ACH95258.1
AY061043 mRNA Translation: AAL28591.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_001261697.1, NM_001274768.1
NP_648432.1, NM_140175.3
NP_729661.1, NM_168439.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0076236; FBpp0075965; FBgn0020412
FBtr0076237; FBpp0075966; FBgn0020412
FBtr0332707; FBpp0304953; FBgn0020412

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
39241

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG6297

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF142061 mRNA Translation: AAD48407.1
AE014296 Genomic DNA Translation: AAF50105.1
AE014296 Genomic DNA Translation: AAN11898.1
BT044484 mRNA Translation: ACH95258.1
AY061043 mRNA Translation: AAL28591.1 Different initiation.
RefSeqiNP_001261697.1, NM_001274768.1
NP_648432.1, NM_140175.3
NP_729661.1, NM_168439.2

3D structure databases

SMRiQ9V3I5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi64615, 13 interactors
IntActiQ9V3I5, 106 interactors
STRINGi7227.FBpp0304953

PTM databases

iPTMnetiQ9V3I5

Proteomic databases

PaxDbiQ9V3I5
PRIDEiQ9V3I5

Genome annotation databases

EnsemblMetazoaiFBtr0076236; FBpp0075965; FBgn0020412
FBtr0076237; FBpp0075966; FBgn0020412
FBtr0332707; FBpp0304953; FBgn0020412
GeneIDi39241
KEGGidme:Dmel_CG6297

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
39241
FlyBaseiFBgn0020412 JIL-1

Phylogenomic databases

eggNOGiKOG0598 Eukaryota
ENOG410XNPH LUCA
GeneTreeiENSGT00940000167362
InParanoidiQ9V3I5
KOiK04445
OMAiVVQKRKT
OrthoDBi1132245at2759
PhylomeDBiQ9V3I5

Enzyme and pathway databases

ReactomeiR-DME-198753 ERK/MAPK targets
R-DME-199920 CREB phosphorylation
R-DME-375165 NCAM signaling for neurite out-growth
R-DME-5621575 CD209 (DC-SIGN) signaling
SignaLinkiQ9V3I5

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
39241

Protein Ontology

More...
PROi
PR:Q9V3I5

Gene expression databases

BgeeiFBgn0020412 Expressed in 28 organ(s), highest expression level in egg chamber
ExpressionAtlasiQ9V3I5 differential
GenevisibleiQ9V3I5 DM

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 2 hits
PF00433 Pkinase_C, 1 hit
SMARTiView protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 2 hits
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJIL1_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9V3I5
Secondary accession number(s): B5RJL0, Q0E8F9, Q95RY3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: May 1, 2000
Last modified: October 16, 2019
This is version 168 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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