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Entry version 154 (12 Aug 2020)
Sequence version 1 (01 May 2000)
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Protein

26S proteasome non-ATPase regulatory subunit 6

Gene

Rpn7

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.4.25.1, 1994

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-1169091, Activation of NF-kappaB in B cells
R-DME-1234176, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
R-DME-1236978, Cross-presentation of soluble exogenous antigens (endosomes)
R-DME-174084, Autodegradation of Cdh1 by Cdh1:APC/C
R-DME-174154, APC/C:Cdc20 mediated degradation of Securin
R-DME-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-DME-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-DME-187577, SCF(Skp2)-mediated degradation of p27/p21
R-DME-195253, Degradation of beta-catenin by the destruction complex
R-DME-202424, Downstream TCR signaling
R-DME-209360, Ubiquitination and proteolysis of phosphorylated CI
R-DME-209406, Degradation of NF-kappa-B inhibitor, CACT
R-DME-209461, Ubiquitination and degradation of phosphorylated ARM
R-DME-216167, Nuclear CI is degraded
R-DME-2467813, Separation of Sister Chromatids
R-DME-2871837, FCERI mediated NF-kB activation
R-DME-350562, Regulation of ornithine decarboxylase (ODC)
R-DME-382556, ABC-family proteins mediated transport
R-DME-432395, Degradation of TIM
R-DME-432524, Degradation of PER
R-DME-432626, Circadian Clock pathway
R-DME-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA
R-DME-4608870, Asymmetric localization of PCP proteins
R-DME-4641257, Degradation of AXIN
R-DME-4641258, Degradation of DVL
R-DME-5358346, Hedgehog ligand biogenesis
R-DME-538864, Degradation of CRY
R-DME-5607761, Dectin-1 mediated noncanonical NF-kB signaling
R-DME-5607764, CLEC7A (Dectin-1) signaling
R-DME-5610780, Degradation of GLI1 by the proteasome
R-DME-5610785, GLI3 is processed to GLI3R by the proteasome
R-DME-5632684, Hedgehog 'on' state
R-DME-5676590, NIK-->noncanonical NF-kB signaling
R-DME-5689603, UCH proteinases
R-DME-5689880, Ub-specific processing proteases
R-DME-6798695, Neutrophil degranulation
R-DME-68827, CDT1 association with the CDC6:ORC:origin complex
R-DME-68949, Orc1 removal from chromatin
R-DME-69017, CDK-mediated phosphorylation and removal of Cdc6
R-DME-69601, Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
R-DME-75815, Ubiquitin-dependent degradation of Cyclin D
R-DME-8854050, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-DME-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs
R-DME-8939902, Regulation of RUNX2 expression and activity
R-DME-8941858, Regulation of RUNX3 expression and activity
R-DME-8948751, Regulation of PTEN stability and activity
R-DME-8951664, Neddylation
R-DME-9020702, Interleukin-1 signaling
R-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
26S proteasome non-ATPase regulatory subunit 6
Alternative name(s):
26S proteasome regulatory subunit S10
Protein Rpn7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rpn7
ORF Names:CG5378
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0028688, Rpn7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Proteasome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001738411 – 38926S proteasome non-ATPase regulatory subunit 6Add BLAST389

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9V3G7

PRoteomics IDEntifications database

More...
PRIDEi
Q9V3G7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0028688, Expressed in adult organism and 38 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9V3G7, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
67596, 36 interactors

Database of interacting proteins

More...
DIPi
DIP-23841N

Protein interaction database and analysis system

More...
IntActi
Q9V3G7, 7 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0083687

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9V3G7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini193 – 361PCIPROSITE-ProRule annotationAdd BLAST169

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the proteasome subunit S10 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0687, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00510000046608

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_031814_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9V3G7

KEGG Orthology (KO)

More...
KOi
K03037

Identification of Orthologs from Complete Genome Data

More...
OMAi
VDYIDQE

Database of Orthologous Groups

More...
OrthoDBi
1194691at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9V3G7

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000717, PCI_dom
IPR035268, PSMD6
IPR019585, Rpn7/CSN1
IPR036390, WH_DNA-bd_sf

The PANTHER Classification System

More...
PANTHERi
PTHR14145:SF1, PTHR14145:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01399, PCI, 1 hit
PF10602, RPN7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00088, PINT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50250, PCI, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9V3G7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPAENLEEQG LEKNPNLELA QTKFLLTLAE YKQDAALKAK LLEAIRTENM
60 70 80 90 100
APWYEHICSE LGWTVDKDLL ARMKENNRVE VEQLDAAIED AEKNLGEMEV
110 120 130 140 150
REANLKKSEY LCRIGDKAAA ETAFRKTYEK TVSLGHRLDI VFHLIRLGLF
160 170 180 190 200
YLDHDLITRN IDKAKYLIEE GGDWDRRNRL KVYQGVYSVA VRDFKAAATF
210 220 230 240 250
FLDTVSTFTS YELMDYPTFV RYTVYVAMIA LPRNELRDKV IKGSEIQEVL
260 270 280 290 300
HGLPDVKQFL FSLYNCQYEN FYVHLAGVEK QLRLDYLIHP HYRYYVREMR
310 320 330 340 350
ILGYTQLLES YRSLTLQYMA ESFGVTVEYI DQELARFIAA GRLHAKVDRV
360 370 380
GGIVETNRPD NKNWQYQATI KQGDLLLNRI QKLSRVINI
Length:389
Mass (Da):45,381
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCCC1DE0C7393B6FA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF145308 mRNA Translation: AAF08389.1
AE014297 Genomic DNA Translation: AAF56000.1
AY052008 mRNA Translation: AAK93432.1

NCBI Reference Sequences

More...
RefSeqi
NP_651048.1, NM_142791.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0084294; FBpp0083687; FBgn0028688

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42641

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5378

UCSC genome browser

More...
UCSCi
CG5378-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF145308 mRNA Translation: AAF08389.1
AE014297 Genomic DNA Translation: AAF56000.1
AY052008 mRNA Translation: AAK93432.1
RefSeqiNP_651048.1, NM_142791.3

3D structure databases

SMRiQ9V3G7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi67596, 36 interactors
DIPiDIP-23841N
IntActiQ9V3G7, 7 interactors
STRINGi7227.FBpp0083687

Proteomic databases

PaxDbiQ9V3G7
PRIDEiQ9V3G7

Genome annotation databases

EnsemblMetazoaiFBtr0084294; FBpp0083687; FBgn0028688
GeneIDi42641
KEGGidme:Dmel_CG5378
UCSCiCG5378-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
42641
FlyBaseiFBgn0028688, Rpn7

Phylogenomic databases

eggNOGiKOG0687, Eukaryota
GeneTreeiENSGT00510000046608
HOGENOMiCLU_031814_0_0_1
InParanoidiQ9V3G7
KOiK03037
OMAiVDYIDQE
OrthoDBi1194691at2759
PhylomeDBiQ9V3G7

Enzyme and pathway databases

BRENDAi3.4.25.1, 1994
ReactomeiR-DME-1169091, Activation of NF-kappaB in B cells
R-DME-1234176, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
R-DME-1236978, Cross-presentation of soluble exogenous antigens (endosomes)
R-DME-174084, Autodegradation of Cdh1 by Cdh1:APC/C
R-DME-174154, APC/C:Cdc20 mediated degradation of Securin
R-DME-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-DME-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-DME-187577, SCF(Skp2)-mediated degradation of p27/p21
R-DME-195253, Degradation of beta-catenin by the destruction complex
R-DME-202424, Downstream TCR signaling
R-DME-209360, Ubiquitination and proteolysis of phosphorylated CI
R-DME-209406, Degradation of NF-kappa-B inhibitor, CACT
R-DME-209461, Ubiquitination and degradation of phosphorylated ARM
R-DME-216167, Nuclear CI is degraded
R-DME-2467813, Separation of Sister Chromatids
R-DME-2871837, FCERI mediated NF-kB activation
R-DME-350562, Regulation of ornithine decarboxylase (ODC)
R-DME-382556, ABC-family proteins mediated transport
R-DME-432395, Degradation of TIM
R-DME-432524, Degradation of PER
R-DME-432626, Circadian Clock pathway
R-DME-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA
R-DME-4608870, Asymmetric localization of PCP proteins
R-DME-4641257, Degradation of AXIN
R-DME-4641258, Degradation of DVL
R-DME-5358346, Hedgehog ligand biogenesis
R-DME-538864, Degradation of CRY
R-DME-5607761, Dectin-1 mediated noncanonical NF-kB signaling
R-DME-5607764, CLEC7A (Dectin-1) signaling
R-DME-5610780, Degradation of GLI1 by the proteasome
R-DME-5610785, GLI3 is processed to GLI3R by the proteasome
R-DME-5632684, Hedgehog 'on' state
R-DME-5676590, NIK-->noncanonical NF-kB signaling
R-DME-5689603, UCH proteinases
R-DME-5689880, Ub-specific processing proteases
R-DME-6798695, Neutrophil degranulation
R-DME-68827, CDT1 association with the CDC6:ORC:origin complex
R-DME-68949, Orc1 removal from chromatin
R-DME-69017, CDK-mediated phosphorylation and removal of Cdc6
R-DME-69601, Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
R-DME-75815, Ubiquitin-dependent degradation of Cyclin D
R-DME-8854050, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-DME-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs
R-DME-8939902, Regulation of RUNX2 expression and activity
R-DME-8941858, Regulation of RUNX3 expression and activity
R-DME-8948751, Regulation of PTEN stability and activity
R-DME-8951664, Neddylation
R-DME-9020702, Interleukin-1 signaling
R-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
42641, 1 hit in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
42641

Protein Ontology

More...
PROi
PR:Q9V3G7

Gene expression databases

BgeeiFBgn0028688, Expressed in adult organism and 38 other tissues
GenevisibleiQ9V3G7, DM

Family and domain databases

InterProiView protein in InterPro
IPR000717, PCI_dom
IPR035268, PSMD6
IPR019585, Rpn7/CSN1
IPR036390, WH_DNA-bd_sf
PANTHERiPTHR14145:SF1, PTHR14145:SF1, 1 hit
PfamiView protein in Pfam
PF01399, PCI, 1 hit
PF10602, RPN7, 1 hit
SMARTiView protein in SMART
SM00088, PINT, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50250, PCI, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPSMD6_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9V3G7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2002
Last sequence update: May 1, 2000
Last modified: August 12, 2020
This is version 154 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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