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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPABY272844:G1GT8-745-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:PYRAB06880
ORF Names:PAB0469
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000810 Componenti: Chromosome
  • UP000009139 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516501 – 625Arginine--tRNA ligaseAdd BLAST625

Interactioni

Protein-protein interaction databases

STRINGi272844.PAB0469

Structurei

3D structure databases

ProteinModelPortaliQ9V0V2
SMRiQ9V0V2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi128 – 138"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 2 hits
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q9V0V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRVKEGAR EKIIKVIESL APGWKGEIEF KDTPSPELGD FGTPVAFKLA
60 70 80 90 100
RVMKKPPFQI AELIVEELKK ELPEGIREVR AINGYVNFFV DYGYLARQLI
110 120 130 140 150
VEVLEKGDRF GSSDIGRGKK VIVEHTSVNP TKPLHMGHAR NAILGDSMAR
160 170 180 190 200
ILRFLGYEVE VQNYIDDLGI QFAQVYWGYL KLREKFEKIM KELKEKGIKE
210 220 230 240 250
DPIDHVLGLL YVEVNRVLEE NPEIEAEIRD IMKKLESGEL NGRELAESVV
260 270 280 290 300
RAQMVTTYRL GIKYDLLVWE SDIVSRKLFE IAVKLLERNE NFYTPNEGKY
310 320 330 340 350
KGAFVMDLSK LFPDMKNPYL VLRRSDGTAT YTGKDIAYHL WKFGKIDVDL
360 370 380 390 400
LYKPWDEHTW TTAPDGESVK GKFGGADIVI NVIGAEQRHP QMAIKHALKL
410 420 430 440 450
LGFEDAAENL HHLAYEHVER PEGKFSGRKG TWVGFTVDEV INEAIKRARE
460 470 480 490 500
LIEEKSPGLS DEEKEEIAEK VGVGAIRYNM VKYSPDKKII FRWEDVLNFE
510 520 530 540 550
GESAPYIQYA HARCSSILRK AGNPEWEALL KEANFKELTE RERELIILLS
560 570 580 590 600
KFPEVVEQAG RDVKPHLIAW YANELASLFN KFYMDHPVIK AEKGIREARL
610 620
LLVMAVRQVL RNSLWLLGIE APDRM
Length:625
Mass (Da):71,691
Last modified:May 1, 2000 - v1
Checksum:iF1B1E7D79AFEC891
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ248285 Genomic DNA Translation: CAB49601.1
HE613800 Genomic DNA Translation: CCE70077.1
PIRiH75110
RefSeqiWP_010867806.1, NC_000868.1

Genome annotation databases

EnsemblBacteriaiCAB49601; CAB49601; PAB0469
GeneIDi1495590
KEGGipab:PAB0469
PATRICifig|272844.11.peg.722

Similar proteinsi

Entry informationi

Entry nameiSYR_PYRAB
AccessioniPrimary (citable) accession number: Q9V0V2
Secondary accession number(s): G8ZJF0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: May 1, 2000
Last modified: February 28, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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