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Protein

Probable electron transfer flavoprotein subunit beta

Gene

SPAC1805.02c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).By similarity

Cofactori

Protein has several cofactor binding sites:
  • FADBy similarityNote: Binds 1 FAD per dimer.By similarity
  • AMPBy similarityNote: Binds 1 AMP per subunit.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport
LigandFAD, Flavoprotein

Enzyme and pathway databases

ReactomeiR-SPO-611105 Respiratory electron transport

Names & Taxonomyi

Protein namesi
Recommended name:
Probable electron transfer flavoprotein subunit beta
Short name:
Beta-ETF
Gene namesi
ORF Names:SPAC1805.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC1805.02c
PomBaseiSPAC1805.02c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001678731 – 254Probable electron transfer flavoprotein subunit betaAdd BLAST254

Proteomic databases

MaxQBiQ9UTH2
PaxDbiQ9UTH2
PRIDEiQ9UTH2

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta subunit.By similarity

Protein-protein interaction databases

BioGridi278849, 5 interactors
STRINGi4896.SPAC1805.02c.1

Structurei

3D structure databases

ProteinModelPortaliQ9UTH2
SMRiQ9UTH2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ETF beta-subunit/FixA family.Curated

Phylogenomic databases

HOGENOMiHOG000247877
InParanoidiQ9UTH2
KOiK03521
OMAiRIPNMRG
OrthoDBiEOG092C3ZW5
PhylomeDBiQ9UTH2

Family and domain databases

CDDicd01714 ETF_beta, 1 hit
Gene3Di3.40.50.620, 1 hit
InterProiView protein in InterPro
IPR000049 ET-Flavoprotein_bsu_CS
IPR014730 ETF_a/b_N
IPR012255 ETF_b
IPR033948 ETF_beta_N
IPR014729 Rossmann-like_a/b/a_fold
PANTHERiPTHR21294 PTHR21294, 1 hit
PfamiView protein in Pfam
PF01012 ETF, 1 hit
PIRSFiPIRSF000090 Beta-ETF, 1 hit
SMARTiView protein in SMART
SM00893 ETF, 1 hit
PROSITEiView protein in PROSITE
PS01065 ETF_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Q9UTH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKIRILVGV KRTLDYMLKP RINATKTAVD LSGQKMSINP FCDIAVEEAI
60 70 80 90 100
RMKETLKNRI EDTLVVTAGQ TSSEPILRQC LAKGIGRAAL INVGEKELEP
110 120 130 140 150
LSVAKLLKAT VEKEKSNLVL LGKQAIDDDA HQTGGMLAAM LGWPQFTSAS
160 170 180 190 200
KVRIEGDKVI VTREIDGGEE TLSSTLPAII TTDLRLNVPR FANLAKVMKA
210 220 230 240 250
RKAPLGKMSP EDLGVTIDQR LQTVSVSEPV QKRQNIMVKS VDEMVKTLKE

LGAL
Length:254
Mass (Da):27,744
Last modified:May 1, 2000 - v1
Checksum:iF05664B69271FE81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB55843.1
PIRiT37887
RefSeqiNP_593913.1, NM_001019342.2

Genome annotation databases

EnsemblFungiiSPAC1805.02c.1; SPAC1805.02c.1:pep; SPAC1805.02c
GeneIDi2542385
KEGGispo:SPAC1805.02c

Similar proteinsi

Entry informationi

Entry nameiETFB_SCHPO
AccessioniPrimary (citable) accession number: Q9UTH2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: May 1, 2000
Last modified: February 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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