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UniProtKB - Q9UT98 (POS5_SCHPO)
Protein
NADH kinase pos5, mitochondrial
Gene
pos5
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Phosphorylates both NADH and NAD+, with a preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH (By similarity).
By similarityCatalytic activityi
- EC:2.7.1.86
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- NAD+ kinase activity Source: GO_Central
- NADH kinase activity Source: PomBase
GO - Biological processi
- NAD metabolic process Source: InterPro
- NADP biosynthetic process Source: PomBase
Keywordsi
Molecular function | Kinase, Transferase |
Ligand | ATP-binding, NAD, NADP, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:pos5 ORF Names:SPAC323.01c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPAC323.01c, pos5 |
VEuPathDBi | FungiDB:SPAC323.01c |
Subcellular locationi
Mitochondrion
- Mitochondrion 1 Publication
Mitochondrion
- mitochondrial matrix Source: PomBase
- mitochondrion Source: PomBase
Keywords - Cellular componenti
MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 42 | MitochondrionSequence analysisAdd BLAST | 42 | |
ChainiPRO_0000316603 | 43 – 386 | NADH kinase pos5, mitochondrialAdd BLAST | 344 |
Proteomic databases
PaxDbi | Q9UT98 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 279603, 3 interactors |
STRINGi | 4896.SPAC323.01c.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the NAD kinase family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG2178, Eukaryota |
HOGENOMi | CLU_008831_10_2_1 |
InParanoidi | Q9UT98 |
OMAi | PFHIDDF |
Family and domain databases
Gene3Di | 2.60.200.30, 1 hit 3.40.50.10330, 1 hit |
HAMAPi | MF_00361, NAD_kinase, 1 hit |
InterProi | View protein in InterPro IPR017438, ATP-NAD_kinase_N IPR017437, ATP-NAD_kinase_PpnK-typ_C IPR016064, NAD/diacylglycerol_kinase_sf IPR002504, NADK |
Pfami | View protein in Pfam PF01513, NAD_kinase, 1 hit |
SUPFAMi | SSF111331, SSF111331, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9UT98-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIRAANGFRI SVRNTAVCLA PNFRQLKGFS IINLGSLQYF RYNSVYSKSI
60 70 80 90 100
RLVNTLENRI VPVYKECASP QSIGGKSNLK QLQWPKPPKN ILILKKRMDE
110 120 130 140 150
RVDHCFETLV QHLQQTYPDI CIITETDVAK KFSYLNLYTW TEISDLEQKV
160 170 180 190 200
DAIITVGGDG TILHAASLFA RSGMPPILSF SLGTLGFLLP FDFGSFQTAF
210 220 230 240 250
ADFYNSRSFV LMRMRLRVAM KTKLYNESIY AMNEMHIHRG LSPHMAVLKV
260 270 280 290 300
FVNDKFLTEA VADGLIISTP TGSTAYSLSS GGPIVHPSIN ALLLTPICPN
310 320 330 340 350
SLSFRPVLFP DTFKISIETS NKSRVRPQLS IDGRPLGLTD IGQRIDITSV
360 370 380
KDNAIPCIIR SHKEDDWVSD IVSLLRWNHP FHRKGW
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB53404.2 |
PIRi | T38638 |
RefSeqi | NP_594371.2, NM_001019792.2 |
Genome annotation databases
EnsemblFungii | SPAC323.01c.1; SPAC323.01c.1:pep; SPAC323.01c |
GeneIDi | 2543173 |
KEGGi | spo:SPAC323.01c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB53404.2 |
PIRi | T38638 |
RefSeqi | NP_594371.2, NM_001019792.2 |
3D structure databases
SMRi | Q9UT98 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 279603, 3 interactors |
STRINGi | 4896.SPAC323.01c.1 |
Proteomic databases
PaxDbi | Q9UT98 |
Genome annotation databases
EnsemblFungii | SPAC323.01c.1; SPAC323.01c.1:pep; SPAC323.01c |
GeneIDi | 2543173 |
KEGGi | spo:SPAC323.01c |
Organism-specific databases
PomBasei | SPAC323.01c, pos5 |
VEuPathDBi | FungiDB:SPAC323.01c |
Phylogenomic databases
eggNOGi | KOG2178, Eukaryota |
HOGENOMi | CLU_008831_10_2_1 |
InParanoidi | Q9UT98 |
OMAi | PFHIDDF |
Miscellaneous databases
PROi | PR:Q9UT98 |
Family and domain databases
Gene3Di | 2.60.200.30, 1 hit 3.40.50.10330, 1 hit |
HAMAPi | MF_00361, NAD_kinase, 1 hit |
InterProi | View protein in InterPro IPR017438, ATP-NAD_kinase_N IPR017437, ATP-NAD_kinase_PpnK-typ_C IPR016064, NAD/diacylglycerol_kinase_sf IPR002504, NADK |
Pfami | View protein in Pfam PF01513, NAD_kinase, 1 hit |
SUPFAMi | SSF111331, SSF111331, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | POS5_SCHPO | |
Accessioni | Q9UT98Primary (citable) accession number: Q9UT98 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 5, 2008 |
Last sequence update: | February 22, 2012 | |
Last modified: | September 29, 2021 | |
This is version 110 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families