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Entry version 131 (02 Jun 2021)
Sequence version 1 (01 May 2000)
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Protein

Primary septum endo-1,3(4)-beta-glucanase

Gene

eng1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Has a role in cell separation where it is required for the degradation of the primary septum after completion of cytokinesis.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.By similarity EC:3.2.1.6

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCell cycle, Cell division

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM52, Carbohydrate-Binding Module Family 52
GH81, Glycoside Hydrolase Family 81

CLAE, a database of fungal genes encoding lignocellulose-active proteins

More...
CLAEi
LAM81A_SCHPO

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Primary septum endo-1,3(4)-beta-glucanase1 Publication
Alternative name(s):
Endo-1,3(4)-beta-glucanase 1 (EC:3.2.1.6By similarity)
Short name:
Endo-1,3-beta-glucanase 1
Short name:
Endo-1,4-beta-glucanase 1
Laminarinase-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:eng11 PublicationImported
ORF Names:SPAC821.09Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPAC821.09, eng1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPAC821.09

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Decreases basal endo-1,3-beta-glucanase activity.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001213221 – 1016Primary septum endo-1,3(4)-beta-glucanaseAdd BLAST996

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi37N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UT45

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UT45

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
279801, 17 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPAC821.09.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UT45

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni844 – 872DisorderedSequence analysisAdd BLAST29

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 81 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2254, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005482_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UT45

Identification of Orthologs from Complete Genome Data

More...
OMAi
ITFMNKI

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UT45

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005200, Endo-beta-glucanase
IPR018909, Eng1_septum
IPR040720, GH81_C
IPR040451, GH81_N

The PANTHER Classification System

More...
PANTHERi
PTHR31983, PTHR31983, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10645, Carb_bind, 3 hits
PF17652, Glyco_hydro81C, 1 hit
PF03639, Glyco_hydro_81, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9UT45-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSYLRSFIF GLLTISLAQC SPILKDTKDT KFSTGSNISL KKRDTNVFDS
60 70 80 90 100
VVDTINPASY FGTVSHPVTP AGVSTDSLSS PIETNKFFDN NLLGSRTNFM
110 120 130 140 150
YADPFRYWWQ SSDTMGGICI AHTDDNQRVM DTDDTIPSYY YEPIGICSLG
160 170 180 190 200
FGASGITSNT DPIVDEIDQM SARFTFSWDS SSMQLTLTEG MAVTTAVYTN
210 220 230 240 250
AIPQIFSSTL YINDFVEVPG TSAVQKYRVT MSDNHVWLIY IYGDSLTLTE
260 270 280 290 300
STSQMLVGSN TFNGYIQIAK IPLGDGTAEA LYDTYAGVYI TGISISGYVE
310 320 330 340 350
DAVGYYSFDF TTAGDTSVEP LFFLLPHQVD TAVSGTKVTS IVLASLVSGD
360 370 380 390 400
MNAAAGNSIT FAEAIPQDIG FLPWSPTGGQ IGYSEEALEI IAEVAGTELG
410 420 430 440 450
EDFSANSNLN SMYYSGKVLA KYAMLCVTIN DILGDETSSE QCIQKLEAAF
460 470 480 490 500
ARFVDNQQIY PLTYDNTWKG VVSVAGLSGD SLADFGNSYY NDHHFHYGYF
510 520 530 540 550
VFTAAVIGHI DPDWINTGNN KEWVNFLVRD VANPSSNDPY FPKHRMIDIY
560 570 580 590 600
HGHGWASGLF ESNDGKDEES TSEDYNFFFG MKLWGQVIGD SDMEDRANII
610 620 630 640 650
LGIERNALNK YMLYADGNVQ PTSMQPNYVA GITFMNKITH TTYFGTNIEY
660 670 680 690 700
IQGIHMLPIT PISAFIRGPS FVLAEWNALL ASVIDYVDSG WRSLLYANLA
710 720 730 740 750
IAEPEESYEY FSSSDFNTDY LDDGASRAWY LAYAAGLWAN DAVYYPVSSS
760 770 780 790 800
STTTTSTSTG SVTTTSTTAT ASCTLPISYT STPTTTSISG TCNGATFDAS
810 820 830 840 850
LYVCDGTVLC PIVNGVSYQN CNGACYNPSQ YGCDNGALGP VQSSSTTSSI
860 870 880 890 900
TPTPTTTSSI TPTPTTTSTT TTAQSTGMQL CGSNYYDASS YYCDNDQLCP
910 920 930 940 950
IIDGVDYLSC NGACYNPSQY VCSDGSLSPN TVTTTKATTT FTPTPTTTTT
960 970 980 990 1000
PTPTTTSATS TNVIAQCGSA WYDSQSYICY GNILCPIING SPLLACGNAC
1010
YDSSIYGCSN GALVAA
Length:1,016
Mass (Da):109,743
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9240CA34D35786FC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB57443.1
AB027918 Genomic DNA Translation: BAA87222.1 Sequence problems.

Protein sequence database of the Protein Information Resource

More...
PIRi
T41720

NCBI Reference Sequences

More...
RefSeqi
NP_593162.1, NM_001018560.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC821.09.1; SPAC821.09.1:pep; SPAC821.09

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2543379

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC821.09

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB57443.1
AB027918 Genomic DNA Translation: BAA87222.1 Sequence problems.
PIRiT41720
RefSeqiNP_593162.1, NM_001018560.2

3D structure databases

SMRiQ9UT45
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi279801, 17 interactors
STRINGi4896.SPAC821.09.1

Protein family/group databases

CAZyiCBM52, Carbohydrate-Binding Module Family 52
GH81, Glycoside Hydrolase Family 81
CLAEiLAM81A_SCHPO

Proteomic databases

MaxQBiQ9UT45
PaxDbiQ9UT45

Genome annotation databases

EnsemblFungiiSPAC821.09.1; SPAC821.09.1:pep; SPAC821.09
GeneIDi2543379
KEGGispo:SPAC821.09

Organism-specific databases

PomBaseiSPAC821.09, eng1
VEuPathDBiFungiDB:SPAC821.09

Phylogenomic databases

eggNOGiKOG2254, Eukaryota
HOGENOMiCLU_005482_2_1_1
InParanoidiQ9UT45
OMAiITFMNKI
PhylomeDBiQ9UT45

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9UT45

Family and domain databases

InterProiView protein in InterPro
IPR005200, Endo-beta-glucanase
IPR018909, Eng1_septum
IPR040720, GH81_C
IPR040451, GH81_N
PANTHERiPTHR31983, PTHR31983, 1 hit
PfamiView protein in Pfam
PF10645, Carb_bind, 3 hits
PF17652, Glyco_hydro81C, 1 hit
PF03639, Glyco_hydro_81, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiENG1_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UT45
Secondary accession number(s): Q9UTZ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: May 1, 2000
Last modified: June 2, 2021
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
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