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UniProtKB - Q9UT43 (YFRD_SCHPO)

Protein

Putative phospholipid-transporting ATPase C821.13c

Gene

SPAC821.13c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei6844-aspartylphosphate intermediateBy similarity1
Metal bindingi1243MagnesiumBy similarity1
Metal bindingi1247MagnesiumBy similarity1

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionTranslocase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-936837 Ion transport by P-type ATPases

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phospholipid-transporting ATPase C821.13c (EC:7.6.2.1)
Gene namesi
ORF Names:SPAC821.13c, SPAC955.01c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces ›
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC821.13c
PomBaseiSPAC821.13c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 275ExtracellularSequence analysisAdd BLAST275
Transmembranei276 – 296HelicalSequence analysisAdd BLAST21
Topological domaini297 – 574CytoplasmicSequence analysisAdd BLAST278
Transmembranei575 – 595HelicalSequence analysisAdd BLAST21
Topological domaini596 – 614ExtracellularSequence analysisAdd BLAST19
Transmembranei615 – 635HelicalSequence analysisAdd BLAST21
Topological domaini636 – 1309CytoplasmicSequence analysisAdd BLAST674
Transmembranei1310 – 1330HelicalSequence analysisAdd BLAST21
Topological domaini1331 – 1332ExtracellularSequence analysis2
Transmembranei1333 – 1353HelicalSequence analysisAdd BLAST21
Topological domaini1354 – 1381CytoplasmicSequence analysisAdd BLAST28
Transmembranei1382 – 1402HelicalSequence analysisAdd BLAST21
Topological domaini1403 – 1414ExtracellularSequence analysisAdd BLAST12
Transmembranei1415 – 1435HelicalSequence analysisAdd BLAST21
Topological domaini1436 – 1443CytoplasmicSequence analysis8
Transmembranei1444 – 1464HelicalSequence analysisAdd BLAST21
Topological domaini1465 – 1490ExtracellularSequence analysisAdd BLAST26
Transmembranei1491 – 1511HelicalSequence analysisAdd BLAST21
Topological domaini1512 – 1562CytoplasmicSequence analysisAdd BLAST51

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000462401 – 1562Putative phospholipid-transporting ATPase C821.13cAdd BLAST1562

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei954Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9UT43
PaxDbiQ9UT43
PRIDEiQ9UT43

PTM databases

iPTMnetiQ9UT43

Interactioni

Protein-protein interaction databases

BioGridi280591, 1 interactor
STRINGi4896.SPAC821.13c.1

Structurei

3D structure databases

ProteinModelPortaliQ9UT43
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi125 – 132Poly-Lys8
Compositional biasi338 – 346Poly-Arg9

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000190484
InParanoidiQ9UT43
KOiK01530
OMAiESWSLSM
OrthoDBiEOG092C0BQ4
PhylomeDBiQ9UT43

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
PANTHERiPTHR24092 PTHR24092, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 1 hit
TIGRFAMsiTIGR01652 ATPase-Plipid, 2 hits
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9UT43-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKSSGIAGDS NGFETNFLNE TTNREEDGAF NWNAADDGTN ERREDIHVRF 
        60         70         80         90        100
QDSALPLGID ENELDEIDIN GDSKKLDSVE VDESHDVNSP SDSRLKSSFK 
       110        120        130        140        150
SVLELTANSM VSVLTPSTKT EQTSKGKGKK KKAHVSFLEG PVEEIPLDDI 
       160        170        180        190        200
EPTSPREASP VFNGRPPIPP EFLKSRHKEF TIPNPLQFIS NFLSNLFSRD 
       210        220        230        240        250
TRYLKSSHGR IIIINPYDDS SQIDERTGKP YMQNSIVSSR YNKYNFVPLQ 
       260        270        280        290        300
IIAQFSKTAN CYFLLIAIMQ MIPGWSTTGT YTTIIPLLIF ISIAILREGF 
       310        320        330        340        350
DNYRRYRQDR VENRIQTQVL RHVDVDPPIV EEHSSFFRRR RWRRSRSQES 
       360        370        380        390        400
ASRSTIRSTD EREPERTSED PPQLPPSPSS PSSPALSVKP NIDPQPPLYN 
       410        420        430        440        450
STLTTTRSIP ANKPTFFWAS CDRKDVRVGD IIRLTSDQTL PADVIALSSP 
       460        470        480        490        500
NPNGAIYIET AALDGETSLK TRLVNSTLRS LCKDINDLIR LSGTCTVEDP 
       510        520        530        540        550
NGDLYNFNGS MKLDSIQGEI PLSNNDVLYR GSNLRNTSEL FALVIFTGEE 
       560        570        580        590        600
SKIRMNAVRN VSVKAPSMQK VTNRIVIFIF ALVVSMAIYC TAAYFVWQKK 
       610        620        630        640        650
VERKLWYLTN SKLSFVPILV SFIILYNTMV PISLYVSMEI IRVFQTFLVQ 
       660        670        680        690        700
SDIDLYYPEN DTRCEVRSSS ILEELGQVTH VFSDKTGTLT DNIMLFRNLS 
       710        720        730        740        750
VGGFAWQHVG AENPKLVSTS QKSDDLDGEA KPPQLENIQG TTIQLLQYVH 
       760        770        780        790        800
DNPHTTFSKR VRIFLLNLAI CHTCLPSFDE ENQIYKYQSI SPDELALVHA 
       810        820        830        840        850
AQQLGYIVID RDIDSLTIRL HYPLDPHSHP IAKTYRILNI IEFTSKRKCM 
       860        870        880        890        900
SVIVRMPNGR ICLFCKGADS AIIKRLRLSN LAKRKDKSVT KAEQARKSIE 
       910        920        930        940        950
IDKAIIRNSQ STSRPSLTAS RPSLSRRRND YINNVTSWLD ERREKMGVVR 
       960        970        980        990       1000
PRASTSILET RRRPAVGRHS LAGGERLMED KKYLSKQEEA EGSIYESLNH 
      1010       1020       1030       1040       1050
NDAKLFENTF EHVHAFATDG LRTLMYAHRF IDESEYQSWK LVNDAALNSL 
      1060       1070       1080       1090       1100
SNRQQLLDEA ADLIEKDLEF AGATAIEDKL QVGVPESINS LFRAGIKFWM 
      1110       1120       1130       1140       1150
LTGDKKETAI NIGHSCGVIK EYSTVVVMGS LDGVEGSDET VSGGQRLSLD 
      1160       1170       1180       1190       1200
RPPTNDPASL MIHQLISCMN AIHSNSLAHL VIVIDGSTLA DIENDPELFL 
      1210       1220       1230       1240       1250
LFINTAVEAD SVICCRSSPM QKALMVQKVR NTLEKAVTLA IGDGANDIAM 
      1260       1270       1280       1290       1300
IQEAHVGIGI AGREGLQAAR SSDFSIGRFK FLIKLLFCHG RWSYVRLSKY 
      1310       1320       1330       1340       1350
ILGTFYKEQF FFLMQAIMQP FVGYTGQSLY ESWGLTCFNT LFSSLCVIGL 
      1360       1370       1380       1390       1400
GIFEKDLSAS TVIAVPELYQ KGINNEAFNW RVYFGWCSIA FIQAFLVFYV 
      1410       1420       1430       1440       1450
TYSLFGMKEL NDNNIFAYGQ LIFTAAIFIM NFKLVFIEMQ YINIISIIVL 
      1460       1470       1480       1490       1500
VLTSLAWFLF NIFISEHYPD KNLYLARSQF LHHFGKNPSW WLTMLFVMVC 
      1510       1520       1530       1540       1550
ALTIDIVAQM LRRTLRPTDT DIFVEMENDA FVRSRFEQES GEFLQANAPS 
      1560 
VDEIEQYLKS RD
Length:1,562
Mass (Da):176,725
Last modified:May 30, 2003 - v2
Checksum:i2B2B138BF8CB5E6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB57447.1
PIRiT41724
RefSeqiXP_001713045.1, XM_001712993.2

Genome annotation databases

EnsemblFungiiSPAC821.13c.1; SPAC821.13c.1:pep; SPAC821.13c
KEGGispo:SPAC821.13c

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB57447.1
PIRiT41724
RefSeqiXP_001713045.1, XM_001712993.2

3D structure databases

ProteinModelPortaliQ9UT43
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi280591, 1 interactor
STRINGi4896.SPAC821.13c.1

PTM databases

iPTMnetiQ9UT43

Proteomic databases

MaxQBiQ9UT43
PaxDbiQ9UT43
PRIDEiQ9UT43

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC821.13c.1; SPAC821.13c.1:pep; SPAC821.13c
KEGGispo:SPAC821.13c

Organism-specific databases

EuPathDBiFungiDB:SPAC821.13c
PomBaseiSPAC821.13c

Phylogenomic databases

HOGENOMiHOG000190484
InParanoidiQ9UT43
KOiK01530
OMAiESWSLSM
OrthoDBiEOG092C0BQ4
PhylomeDBiQ9UT43

Enzyme and pathway databases

ReactomeiR-SPO-936837 Ion transport by P-type ATPases

Miscellaneous databases

PROiPR:Q9UT43

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
PANTHERiPTHR24092 PTHR24092, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 1 hit
TIGRFAMsiTIGR01652 ATPase-Plipid, 2 hits
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiYFRD_SCHPO
AccessioniPrimary (citable) accession number: Q9UT43
Secondary accession number(s): Q9P6S8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: November 7, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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