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Protein

Mitochondrial transcription factor 1

Gene

mtf1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei38S-adenosyl-L-methionine; via amide nitrogenPROSITE-ProRule annotation1
Binding sitei91S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei117S-adenosyl-L-methioninePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

  • positive regulation of mitochondrial transcription Source: PomBase
  • positive regulation of transcription by RNA polymerase II Source: PomBase

Keywordsi

Molecular functionDNA-binding, Methyltransferase, RNA-binding, Transferase
Biological processTranscription, Transcription regulation
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial transcription factor 1 (EC:2.1.1.-)
Gene namesi
Name:mtf1
ORF Names:SPAC1002.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC1002.08c
PomBaseiSPAC1002.08c mtf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003166061 – 366Mitochondrial transcription factor 1Add BLAST366

Proteomic databases

MaxQBiQ9US51
PaxDbiQ9US51
PRIDEiQ9US51

Interactioni

Protein-protein interaction databases

BioGridi279699, 4 interactors
STRINGi4896.SPAC1002.08c.1

Structurei

3D structure databases

ProteinModelPortaliQ9US51
SMRiQ9US51
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiQ9US51
KOiK15267
OMAiCKLSVIA
OrthoDBiEOG092C25UQ
PhylomeDBiQ9US51

Family and domain databases

Gene3Di1.10.8.100, 1 hit
InterProiView protein in InterPro
IPR001737 KsgA/Erm
IPR023165 rRNA_Ade_diMease-like
IPR029063 SAM-dependent_MTases
PANTHERiPTHR11727 PTHR11727, 1 hit
PfamiView protein in Pfam
PF00398 RrnaAD, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS51689 SAM_RNA_A_N6_MT, 1 hit

Sequencei

Sequence statusi: Complete.

Q9US51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLPKILYDA AAFGGPRSTG FVKILNLNGR SSYKSSYLVN QNLMDEALVK
60 70 80 90 100
SNLLKEYNSE KMTILEMAPG PGVTTTSLFN YFQPKSHVVL ESREVFSKPL
110 120 130 140 150
QKLCTLSDGR IKWVHQDGYY WQTYEDVYVS KVLDPRIQTE EEQKLSPHRE
160 170 180 190 200
LLFFAHLPHG YAGLLFVSQI LDFLSARDWL GIFGRVRVLL WLPCSPTVTL
210 220 230 240 250
LGSRGFSKRS KTSVFREAFT DSRVLAASES TLQKLCMGYS KEAKENYQIS
260 270 280 290 300
PNPLLVSPTP ITSEPHKEDL TLVEMCSKPQ DKQLSIPVFE SIVRILLTCK
310 320 330 340 350
ATSLSKSIYY LGPGAETLLP SFTQCGINID MPVGLLSAAD FLTISKIIQK
360
YPFKHHLHLG TIIEDS
Length:366
Mass (Da):41,198
Last modified:May 1, 2000 - v1
Checksum:i29923DDD861B75E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB65608.1
RefSeqiNP_593495.1, NM_001018929.2

Genome annotation databases

EnsemblFungiiSPAC1002.08c.1; SPAC1002.08c.1:pep; SPAC1002.08c
GeneIDi2543271
KEGGispo:SPAC1002.08c

Entry informationi

Entry nameiMTF1_SCHPO
AccessioniPrimary (citable) accession number: Q9US51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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